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Sources of Cognitive Exploration

Title: Sources of Cognitive Exploration: Genetic Variation in the Prefrontal Dopamine System Predicts Openness/Intellect.
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Name(s): Deyoung, Colin G, author
Cicchetti, Dante, author
Rogosch, Fred A, author
Gray, Jeremy R, author
Eastman, Maria, author
Grigorenko, Elena L, author
Type of Resource: text
Genre: Text
Date Issued: 2011-08-01
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: The personality trait Openness/Intellect reflects the tendency to be imaginative, curious, perceptive, artistic, and intellectual-all characteristics that involve cognitive exploration. Little is known about the biological basis of Openness/Intellect, but the trait has been linked to cognitive functions of prefrontal cortex, and the neurotransmitter dopamine plays a key role in motivation to explore. The hypothesis that dopamine is involved in Openness/Intellect was supported by examining its association with two genes that are central components of the prefrontal dopaminergic system. In two demographically different samples (children: N = 608; adults: N = 214), variation in the dopamine D4 receptor gene (DRD4) and the catechol-O-methyltransferase gene (COMT) predicted Openness/Intellect, as main effects in the child sample and in interaction in adults.
Identifier: FSU_pmch_21804655 (IID), 10.1016/j.jrp.2011.04.002 (DOI), PMC3143482 (PMCID), 21804655 (RID), 21804655 (EID)
Grant Number: F32 MH077382, F32 MH077382-03, P50 HD052120, P50 HD052120-05, R01 DA012903, R01 DA012903-05, R01 DA017741, R01 DA017741-01S1
Publication Note: This NIH-funded author manuscript originally appeared in PubMed Central at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143482.
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_pmch_21804655
Owner Institution: FSU
Is Part Of: Journal of research in personality.
0092-6566
Issue: iss. 4, vol. 45

Choose the citation style.
Deyoung, C. G., Cicchetti, D., Rogosch, F. A., Gray, J. R., Eastman, M., & Grigorenko, E. L. (2011). Sources of Cognitive Exploration: Genetic Variation in the Prefrontal Dopamine System Predicts Openness/Intellect. Journal Of Research In Personality. Retrieved from http://purl.flvc.org/fsu/fd/FSU_pmch_21804655