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Prevalence and Factors Associated With Statin Use Among a Nationally Representative Sample of US Adults

Title: Prevalence and Factors Associated With Statin Use Among a Nationally Representative Sample of US Adults: National Health and Nutrition Examination Survey, 2011-2012.
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Name(s): Adedinsewo, Demilade, author
Taka, Nchang, author
Agasthi, Pradyumna, author
Sachdeva, Rajesh, author
Rust, George, author
Onwuanyi, Anekwe, author
Type of Resource: text
Genre: Journal Article
Text
Date Issued: 2016-09-01
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: The 2013 American College of Cardiology/American Heart Association guidelines recommend statins for adults age ≤75 years who have clinical atherosclerotic cardiovascular disease (IA) and adults age 40 to 75 years with diabetes mellitus and LDL-C 70-189 mg/dl (IA). Our aim was to estimate the prevalence and likelihood of statin use among selected statin benefit groups. Using data from the National Health and Nutrition Examination Survey (NHANES) 2011-2012, we examined 5319 adults age ≥20 years. We estimated weighted frequencies and prevalence of statin use for adults with diabetes mellitus and dyslipidemia (or low-density lipoprotein cholesterol ≥70 mg/dL), defined as statin benefit group 1 (SBG1); and for adults with atherosclerotic cardiovascular disease, defined as statin benefit group 2 (SBG2). We constructed a logistic regression model to estimate odds of statin use in SBG1. Overall, an estimated 38.6 million Americans are on a statin. In adjusted models, uninsured and Hispanic adults were less likely to be on a statin compared with white adults; 59.5% (95% confidence interval [CI]: 53.0-66.1) of all adults in SBG1, 58.8% (95% CI: 51.5-66.1) of adults age 40 to 75 in SBG1, and 63.5% (95% CI: 55.6-71.4) of all adults in SBG2 were on a statin. Although the prevalence of statin use has increased over time, Hispanic ethnicity and lack of insurance remain barriers to statin use. Black-white racial disparities were not significant. Our study provides a baseline estimate of statin use in the noninstitutionalized population just prior to introduction of the new guidelines and provides a reference for evaluating the impact of the new guidelines on statin utilization.
Identifier: FSU_pmch_27505443 (IID), 10.1002/clc.22577 (DOI), PMC5030167 (PMCID), 27505443 (RID), 27505443 (EID)
Keywords: Clinical, Epidemiology, Lipidology, Pharmacology, Preventive cardiology
Grant Number: K18 HS022444, P20 MD006881, U54 MD007588
Publication Note: This NIH-funded author manuscript originally appeared in PubMed Central at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030167.
Subject(s): Adult
African Americans
Age Factors
Aged
Atherosclerosis/blood
Atherosclerosis/diagnosis
Atherosclerosis/drug therapy
Atherosclerosis/ethnology
Chi-Square Distribution
Comorbidity
Diabetes Mellitus/ethnology
Dyslipidemias/blood
Dyslipidemias/diagnosis
Dyslipidemias/drug therapy
Dyslipidemias/ethnology
European Continental Ancestry Group
Female
Healthcare Disparities/ethnology
Hispanic Americans
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use
Logistic Models
Male
Middle Aged
Multivariate Analysis
Nutrition Surveys
Odds Ratio
Practice Guidelines as Topic
Prevalence
Risk Factors
Time Factors
United States/epidemiology
Young Adult
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_pmch_27505443
Host Institution: FSU
Is Part Of: Clinical cardiology.
1932-8737
Issue: iss. 9, vol. 39

Choose the citation style.
Adedinsewo, D., Taka, N., Agasthi, P., Sachdeva, R., Rust, G., & Onwuanyi, A. (2016). Prevalence and Factors Associated With Statin Use Among a Nationally Representative Sample of US Adults: National Health and Nutrition Examination Survey, 2011-2012. Clinical Cardiology. Retrieved from http://purl.flvc.org/fsu/fd/FSU_pmch_27505443