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Title: Population Variation In The Trophic Niche Of The Trinidadian Guppy From Different Predation Regimes.
Creator: Zandona, Eugenia, Dalton, Christopher M., El-Sabaawi, Rana W., Howard, Jason L., Marshall, Michael C., Kilham, Susan S., Reznick, David N., Travis, Joseph, Kohler, Tyler J.,...
Show moreZandona, Eugenia, Dalton, Christopher M., El-Sabaawi, Rana W., Howard, Jason L., Marshall, Michael C., Kilham, Susan S., Reznick, David N., Travis, Joseph, Kohler, Tyler J., Flecker, Alexander S., Thomas, Steven A., Pringle, Catherine M.
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Abstract/Description: Population variation in trophic niche is widespread among organisms and is of increasing interest given its role in both speciation and adaptation to changing environments. Trinidadian guppies (Poecilia reticulata) inhabiting stream reaches with different predation regimes have rapidly evolved divergent life history traits. Here, we investigated the effects of both predation and resource availability on guppy trophic niches by evaluating their gut contents, resource standing stocks, and delta...
Show morePopulation variation in trophic niche is widespread among organisms and is of increasing interest given its role in both speciation and adaptation to changing environments. Trinidadian guppies (Poecilia reticulata) inhabiting stream reaches with different predation regimes have rapidly evolved divergent life history traits. Here, we investigated the effects of both predation and resource availability on guppy trophic niches by evaluating their gut contents, resource standing stocks, and delta N-15 and delta C-13 stable isotopes across five streams during the wet season. We found that guppies from low predation (LP) sites had a consistently higher trophic position and proportion of invertebrates in their guts and assimilate less epilithon than guppies from high predation (HP) sites. Higher trophic position was also associated with lower benthic invertebrate availability. Our results suggest that LP guppies could be more efficient invertebrate consumers, possibly as an evolutionary response to greater intraspecific competition for higher quality food. This may be intensified by seasonality, as wet season conditions can alter resource availability, feeding rates, and the intensity of intraspecific competition. Understanding how guppy diets vary among communities is critical to elucidating the role of niche shifts in mediating the link between environmental change and the evolution of life histories.
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Date Issued: 2017-07-18
Identifier: FSU_libsubv1_wos_000405746500081, 10.1038/s41598-017-06163-6
Format: Citation

Title: Measurement Of Inclusive Jet Cross Sections In Pp And Pbpb Collisions At Root S(nn)=2.76 Tev.
Creator: Khachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth...
Show moreKhachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schieck, J., Strauss, J., Waltenberger, W., Wulz, C.-E., Mossolov, V., Shumeiko, N., Gonzalez, J. Suarez, Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., De Klundert, M. Van, Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, F., D'Hondt, J., Daci, N., De Bruyn, I., Deroover, K., Heracleous, N., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Caillol, C., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Leonard, A., Luetic, J., Maerschalk, T., Marinov, A., Randle-Conde, A., Seva, T., Velde, C. Vander, Vanlaer, P., Yonamine, R., Zenoni, F., Zhang, F., Cimmino, A., Cornelis, T., Dobur, D., Fagot, A., Garcia, G., Gul, M., Poyraz, D., Salva, S., Schofbeck, R., Sharma, A., Tytgat, M., Van Driessche, W., Yazgan, E., Zaganidis, N., Bakhshiansohi, H., Beluffi, C., Bondu, O., Brochet, S., Bruno, G., Caudron, A., De Visscher, S., Delaere, C., Delcourt, M., Francois, B., Giammanco, A., Jafari, A., Jez, P., Komm, M., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Nuttens, C., Piotrzkowski, K., Quertenmont, L., Selvaggi, M., Marono, M. Vidal, Wertz, S., Beliy, N., Alda Junior, W. L., Alves, F. L., Alves, G. A., Brito, L., Hensel, C., Moraes, A., Pol, M. E., Rebello Teles, P., Belchior Batista Das Chagas, E., Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Huertas Guativa, L. M., Malbouisson, H., Matos Figueiredo, D., Mora Herrera, C., Mundim, L., Nogima, H., Prado Da Silva, W. L., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Vilela Pereira, A., Ahuja, S., Bernardes, C. A., Dogra, S., Fernandez Perez Tomei, T. R., Gregores, E. M., Mercadante, P. G., Moon, C. S., Novaes, S. F., Padula, Sandra S., Romero Abad, D., Ruiz Vargas, J. C., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Rodozov, M., Stoykova, S., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Litov, L., Pavlov, B., Petkov, P., Fang, W., Ahmad, M., Bian, J. G., Chen, G. M., Chen, H. S., Chen, M., Chen, Y., Cheng, T., Jiang, C. H., Leggat, D., Liu, Z., Romeo, F., Shaheen, S. M., Spiezia, A., Tao, J., Wang, C., Wang, Z., Zhang, H., Zhao, J., Ban, Y., Chen, G., Li, Q., Liu, S., Mao, Y., Qian, S. J., Wang, D., Xu, Z., Avila, C., Cabrera, A., Chaparro Sierra, L. F., Florez, C., Gomez, J. P., Gonzalez Hernandez, C. F., Ruiz Alvarez, J. D., Sanabria, J. C., Godinovic, N., Lelas, D., Puljak, I., Cipriano, P. M. Ribeiro, Sculac, T., Antunovic, Z., Kovac, M., Brigljevic, V., Ferencek, D., Kadija, K., Micanovic, S., Sudic, L., Susa, T., Attikis, A., Mavromanolakis, G., Mousa, J., Nicolaou, C., Ptochos, F., Razis, P. A., Rykaczewski, H., Finger, M., Finger, M., Carrera Jarrin, E., El-Khateeb, E., Elgammal, S., Mohamed, A., Calpas, B., Kadastik, M., Murumaa, M., Perrini, L., Raidal, M., Tiko, A., Veelken, C., Eerola, P., Pekkanen, J., Voutilainen, M., Harkonen, J., Karimaki, V., Kinnunen, R., Lampen, T., Lassila-Perini, K., Lehti, S., Linden, T., Luukka, P., Tuominiemi, J., Tuovinen, E., Wendland, L., Talvitie, J., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Fabbro, B., Faure, J. L., Favaro, C., Ferri, F., Ganjour, S., Ghosh, S., Givernaud, A., Gras, P., de Monchenault, G. 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L., Perries, S., Popov, A., Sabes, D., Sordini, V., Donckt, M. Vander, Verdier, P., Viret, S., Khvedelidze, A., Tsamalaidze, Z., Autermann, C., Beranek, S., Feld, L., Heister, A., Kiesel, M. K., Klein, K., Lipinski, M., Ostapchuk, A., Preuten, M., Raupach, F., Schael, S., Schomakers, C., Schulz, J., Verlage, T., Weber, H., Zhukov, V., Albert, A., Brodski, M., Dietz-Laursonn, E., Duchardt, D., Endres, M., Erdmann, M., Erdweg, S., Esch, T., Fischer, R., Gueth, A., Hamer, M., Hebbeker, T., Heidemann, C., Hoepfner, K., Knutzen, S., Merschmeyer, M., Meyer, A., Millet, P., Mukherjee, S., Olschewski, M., Padeken, K., Pook, T., Radziej, M., Reithler, H., Rieger, M., Scheuch, F., Sonnenschein, L., Teyssier, D., Thueer, S., Cherepanov, V., Fluegge, G., Hoehle, F., Kargoll, B., Kress, T., Kuensken, A., Lingemann, J., Mueller, T., Nehrkorn, A., Nowack, A., Nugent, I. M., Pistone, C., Pooth, O., Stahl, A., Martin, M. Aldaya, Arndt, T., Asawatangtrakuldee, C., Beernaert, K., Behnke, O., Behrens, U., Bin Anuar, A. A., Borras, K., Campbell, A., Connor, P., Contreras-Campana, C., Costanza, F., Pardos, C. Diez, Dolinska, G., Eckerlin, G., Eckstein, D., Eichhorn, T., Eren, E., Gallo, E., Garcia, J. Garay, Geiser, A., Gizhko, A., Luyando, J. M. Grados, Gunnellini, P., Harb, A., Hauk, J., Hempel, M., Jung, H., Kalogeropoulos, A., Karacheban, O., Kasemann, M., Keaveney, J., Kleinwort, C., Korol, I., Kruecker, D., Lange, W., Lelek, A., Leonard, J., Lipka, K., Lobanov, A., Lohmann, W., Mankel, R., Melzer-Pellmann, I.-A., Meyer, A. B., Mittag, G., Mnich, J., Mussgiller, A., Ntomari, E., Pitzl, D., Placakyte, R., Raspereza, A., Roland, B., Sahin, M. Oe, Saxena, P., Schoerner-Sadenius, T., Seitz, C., Spannagel, S., Stefaniuk, N., Van Onsem, G. P., Walsh, R., Wissing, C., Blobel, V., Vignali, M. Centis, Draeger, A. R., Dreyer, T., Garutti, E., Gonzalez, D., Haller, J., Hoffmann, M., Junkes, A., Klanner, R., Kogler, R., Kovalchuk, N., Lapsien, T., Lenz, T., Marchesini, I., Marconi, D., Meyer, M., Niedziela, M., Nowatschin, D., Pantaleo, F., Peiffer, T., Perieanu, A., Poehlsen, J., Sander, C., Scharf, C., Schleper, P., Schmidt, A., Schumann, S., Schwandt, J., Stadie, H., Steinbrueck, G., Stober, F. M., Stoever, M., Tholen, H., Troendle, D., Usai, E., Vanelderen, L., Vanhoefer, A., Vormwald, B., Barth, C., Baus, C., Berger, J., Butz, E., Chwalek, T., Colombo, F., De Boer, W., Dierlamm, A., Fink, S., Friese, R., Giffels, M., Gilbert, A., Goldenzweig, P., Haitz, D., Hartmann, F., Heindl, S. M., Husemann, U., Katkov, I., Pardo, P. Lobelle, Maier, B., Mildner, H., Mozer, M. U., Mueller, Th, Plagge, M., Quast, G., Rabbertz, K., Roecker, S., Roscher, F., Schroeder, M., Shvetsov, I., Sieber, G., Simonis, H. J., Ulrich, R., Wagner-Kuhr, J., Wayand, S., Weber, M., Weiler, T., Williamson, S., Woehrmann, C., Wolf, R., Anagnostou, G., Daskalakis, G., Geralis, T., Giakoumopoulou, V. A., Kyriakis, A., Loukas, D., Topsis-Giotis, I., Kesisoglou, S., Panagiotou, A., Saoulidou, N., Tziaferi, E., Evangelou, I., Flouris, G., Foudas, C., Kokkas, P., Loukas, N., Manthos, N., Papadopoulos, I., Paradas, E., Filipovic, N., Bencze, G., Hajdu, C., Hidas, P., Horvath, D., Sikler, F., Veszpremi, V., Vesztergombi, G., Zsigmond, A. J., Beni, N., Czellar, S., Karancsi, J., Makovec, A., Molnar, J., Szillasi, Z., Bartok, M., Raics, P., Trocsanyi, Z. L., Ujvari, B., Bahinipati, S., Choudhury, S., Mal, P., Mandal, K., Nayak, A., Sahoo, D. K., Sahoo, N., Swain, S. K., Bansal, S., Beri, S. B., Bhatnagar, V., Chawla, R., Bhawandeep, U., Kalsi, A. K., Kaur, A., Kaur, M., Kumar, R., Kumari, P., Mehta, A., Mittal, M., Singh, J. B., Walia, G., Kumar, Ashok, Bhardwaj, A., Choudhary, B. C., Garg, R. B., Keshri, S., Malhotra, S., Naimuddin, M., Nishu, N., Ranjan, K., Sharma, R., Sharma, V., Bhattacharya, R., Bhattacharya, S., Chatterjee, K., Dey, S., Dutt, S., Dutta, S., Ghosh, S., Majumdar, N., Modak, A., Mondal, K., Mukhopadhyay, S., Nandan, S., Purohit, A., Roy, A., Roy, D., Chowdhury, S. Roy, Sarkar, S., Sharan, M., Thakur, S., Behera, P. K., Chudasama, R., Dutta, D., Jha, V., Kumar, V., Mohanty, A. K., Netrakanti, P. K., Pant, L. M., Shukla, P., Topkar, A., Aziz, T., Dugad, S., Kole, G., Mahakud, B., Mitra, S., Mohanty, G. B., Parida, B., Sur, N., Sutar, B., Banerjee, S., Bhowmik, S., Dewanjee, R. K., Ganguly, S., Guchait, M., Jain, Sa, Kumar, S., Maity, M., Majumder, G., Mazumdar, K., Sarkar, T., Wickramage, N., Chauhan, S., Dube, S., Hegde, V., Kapoor, A., Kothekar, K., Rane, A., Sharma, S., Behnamian, H., Chenarani, S., Tadavani, E. Eskandari, Etesami, S. M., Fahim, A., Khakzad, M., Najafabadi, M. Mohammadi, Naseri, M., Mehdiabadi, S. Paktinat, Hosseinabadi, F. 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P., Tosi, N., Albergo, S., Chiorboli, M., Costa, S., Di Mattia, A., Giordano, F., Potenza, R., Tricomi, A., Tuve, C., Barbagli, G., Ciulli, V., Civinini, C., D'Alessandro, R., Focardi, E., Gori, V., Lenzi, P., Meschini, M., Paoletti, S., Sguazzoni, G., Viliani, L., Benussi, L., Bianco, S., Fabbri, F., Piccolo, D., Primavera, F., Calvelli, V., Ferro, F., Lo Vetere, M., Monge, M. R., Robutti, E., Tosi, S., Brianza, L., Dinardo, M. E., Fiorendi, S., Gennai, S., Ghezzi, A., Govoni, P., Malberti, M., Malvezzi, S., Manzoni, R. A., Menasce, D., Moroni, L., Paganoni, M., Pedrini, D., Pigazzini, S., Ragazzi, S., de Fatis, T. Tabarelli, Buontempo, S., Cavallo, N., De Nardo, G., Di Guida, S., Esposito, M., Fabozzi, F., Fienga, F., Iorio, A. O. M., Lanza, G., Lista, L., Meola, S., Paolucci, P., Sciacca, C., Thyssen, F., Azzi, P., Bacchetta, N., Benato, L., Bisello, D., Boletti, A., Carlin, R., De Oliveira, A. Carvalho Antunes, Checchia, P., Dall'Osso, M., Manzano, P. De Castro, Dorigo, T., Dosselli, U., Gasparini, F., Gasparini, U., Gozzelino, A., Lacaprara, S., Margoni, M., Meneguzzo, A. T., Pazzini, J., Pozzobon, N., Ronchese, P., Simonetto, F., Torassa, E., Zanetti, M., Zotto, P., Zumerle, G., Braghieri, A., Magnani, A., Montagna, P., Ratti, S. P., Re, V., Riccardi, C., Salvini, P., Vai, I., Vitulo, P., Solestizi, L. Alunni, Bilei, G. M., Ciangottini, D., Fano, L., Lariccia, P., Leonardi, R., Mantovani, G., Menichelli, M., Saha, A., Santocchia, A., Androsov, K., Azzurri, P., Bagliesi, G., Bernardini, J., Boccali, T., Castaldi, R., Ciocci, M. A., Dell'Orso, R., Donato, S., Fedi, G., Giassi, A., Grippo, M. T., Ligabue, F., Lomtadze, T., Martini, L., Messineo, A., Palla, F., Rizzi, A., Savoy-Navarro, A., Spagnolo, P., Tenchini, R., Tonelli, G., Venturi, A., Verdini, P. 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F., Missiroli, M., Moran, D., Cuevas, J., Fernandez Menendez, J., Gonzalez Caballero, I., Gonzalez Fernandez, J. R., Palencia Cortezon, E., Sanchez Cruz, S., Suarez Andres, I., Vizan Garcia, J. M., Cabrillo, I. J., Calderon, A., Castineiras De Saa, J. R., Curras, E., Fernandez, M., Garcia-Ferrero, J., Gomez, G., Lopez Virto, A., Marco, J., Martinez Rivero, C., Matorras, F., Piedra Gomez, J., Rodrigo, T., Ruiz-Jimeno, A., Scodellaro, L., Trevisani, N., Vila, I., Vilar Cortabitarte, R., Abbaneo, D., Auffray, E., Auzinger, G., Bachtis, M., Baillon, P., Ball, A. 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A., Dasu, S., Dodd, L., Duric, S., Gomber, B., Grothe, M., Herndon, M., Herve, A., Klabbers, P., Lanaro, A., Levine, A., Long, K., Loveless, R., Ojalvo, I., Perry, T., Pierro, G. A., Polese, G., Ruggles, T., Savin, A., Smith, N., Smith, W. H., Taylor, D., Woods, N.
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Abstract/Description: Inclusive jet spectra from pp and PbPb collisions at a nucleon-nucleon center-of-mass energy of 2.76 TeV, collected with the CMS detector at the CERN Large Hadron Collider, are presented. Jets are reconstructed with three different distance parameters (R = 0.2, 0.3, and 0.4) for transverse momentum (p(T)) greater than 70 GeV/c and pseudorapidity |eta| < 2. Next-to-leading-order quantum chromodynamic calculations with nonperturbative corrections are found to overpredict jet production cross...
Show moreInclusive jet spectra from pp and PbPb collisions at a nucleon-nucleon center-of-mass energy of 2.76 TeV, collected with the CMS detector at the CERN Large Hadron Collider, are presented. Jets are reconstructed with three different distance parameters (R = 0.2, 0.3, and 0.4) for transverse momentum (p(T)) greater than 70 GeV/c and pseudorapidity |eta| < 2. Next-to-leading-order quantum chromodynamic calculations with nonperturbative corrections are found to overpredict jet production cross sections in pp for small distance parameters. The jet nuclear modification factors for PbPb compared to pp collisions, show a steady decrease from peripheral to central events, along with a weak dependence on the jet p(T). They are found to be independent of the distance parameter in the measured kinematic range.
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Date Issued: 2017-07-17
Identifier: FSU_libsubv1_wos_000405709100007, 10.1103/PhysRevC.96.015202
Format: Citation

Title: Possible Devil's Staircase In The Kondo Lattice Cesbse.
Creator: Chen, K.-W., Lai, Y., Chiu, Y.-C., Steven, S., Besara, T., Graf, D., Siegrist, T., Albrecht-Schmitt, T. E., Balicas, L., Baumbach, R. E.
Abstract/Description: The temperature- (T) magnetic-field (H) phase diagram for the tetragonal layered compound CeSbSe is determined from magnetization, specific heat, and electrical resistivity measurements. This system exhibits complex magnetic ordering at T-M = 3 K and the application of a magnetic field results in a cascade of magnetically ordered states for H less than or similar to 1.8 T which are characterized by fractional integer size steps: i.e., a possible devil's staircase is observed. Electrical...
Show moreThe temperature- (T) magnetic-field (H) phase diagram for the tetragonal layered compound CeSbSe is determined from magnetization, specific heat, and electrical resistivity measurements. This system exhibits complex magnetic ordering at T-M = 3 K and the application of a magnetic field results in a cascade of magnetically ordered states for H less than or similar to 1.8 T which are characterized by fractional integer size steps: i.e., a possible devil's staircase is observed. Electrical transport measurements show a weak temperature dependence and large residual resistivity which suggest a small charge-carrier density and strong scattering from the f moments. These features reveal Kondo lattice behavior where the f moments are screened incompletely, resulting in a fine balanced magnetic interaction between different Ce neighbors that is mediated by the Ruderman-Kittel-Kasuya-Yosida interaction. This produces the nearly degenerate magnetically ordered states that are accessed under an applied magnetic field.
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Date Issued: 2017-07-17
Identifier: FSU_libsubv1_wos_000405697200002, 10.1103/PhysRevB.96.014421
Format: Citation

Title: Working Memory and Organizational Skills Problems in ADHD.
Creator: Kofler, Michael J., Sarver, Dustin E., Harmon, Sherelle L., Moltisanti, Allison, Aduen, Paula A., Soto, Elia F., Ferretti, Nicole
Date Issued: 2017-07-17
Identifier: FSU_libsubv1_scholarship_submission_1507138446_b645b061, 10.1111/jcpp.12773
Format: Citation

Title: Genotype-specific pathogenic effects in human dilated cardiomyopathy.
Creator: Bollen, Ilse A E, Schuldt, Maike, Harakalova, Magdalena, Vink, Aryan, Asselbergs, Folkert W, Pinto, Jose R, Krüger, Martina, Kuster, Diederik W D, van der Velden, Jolanda
Abstract/Description: Mutations in genes encoding cardiac troponin I (TNNI3) and cardiac troponin T (TNNT2) caused altered troponin protein stoichiometry in patients with dilated cardiomyopathy. TNNI3p.98trunc resulted in haploinsufficiency, increased Ca(2+) -sensitivity and reduced length-dependent activation. TNNT2p.K217del caused increased passive tension. A mutation in the gene encoding Lamin A/C (LMNAp.R331Q ) led to reduced maximal force development through secondary disease remodelling in patients suffering...
Show moreMutations in genes encoding cardiac troponin I (TNNI3) and cardiac troponin T (TNNT2) caused altered troponin protein stoichiometry in patients with dilated cardiomyopathy. TNNI3p.98trunc resulted in haploinsufficiency, increased Ca(2+) -sensitivity and reduced length-dependent activation. TNNT2p.K217del caused increased passive tension. A mutation in the gene encoding Lamin A/C (LMNAp.R331Q ) led to reduced maximal force development through secondary disease remodelling in patients suffering from dilated cardiomyopathy. Our study shows that different gene mutations induce dilated cardiomyopathy via diverse cellular pathways. Dilated cardiomyopathy (DCM) can be caused by mutations in sarcomeric and non-sarcomeric genes. In this study we defined the pathogenic effects of three DCM-causing mutations: the sarcomeric mutations in genes encoding cardiac troponin I (TNNI3p.98truncation ) and cardiac troponin T (TNNT2p.K217deletion ; also known as the p.K210del) and the non-sarcomeric gene mutation encoding lamin A/C (LMNAp.R331Q ). We assessed sarcomeric protein expression and phosphorylation and contractile behaviour in single membrane-permeabilized cardiomyocytes in human left ventricular heart tissue. Exchange with recombinant troponin complex was used to establish the direct pathogenic effects of the mutations in TNNI3 and TNNT2. The TNNI3p.98trunc and TNNT2p.K217del mutation showed reduced expression of troponin I to 39% and 51%, troponin T to 64% and 53%, and troponin C to 73% and 97% of controls, respectively, and altered stoichiometry between the three cardiac troponin subunits. The TNNI3p.98trunc showed pure haploinsufficiency, increased Ca(2+) -sensitivity and impaired length-dependent activation. The TNNT2p.K217del mutation showed a significant increase in passive tension that was not due to changes in titin isoform composition or phosphorylation. Exchange with wild-type troponin complex corrected troponin protein levels to 83% of controls in the TNNI3p.98trunc sample. Moreover, upon exchange all functional deficits in the TNNI3p.98trunc and TNNT2p.K217del samples were normalized to control values confirming the pathogenic effects of the troponin mutations. The LMNAp.R331Q mutation resulted in reduced maximal force development due to disease remodelling. Our study shows that different gene mutations induce DCM via diverse cellular pathways.
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Date Issued: 2017-07-15
Identifier: FSU_pmch_28436080, 10.1113/JP274145, PMC5509872, 28436080, 28436080
Format: Citation

Title: Measurement Of The Jet Mass In Highly Boosted T(t)over-bar Events From Pp Collisions At Root S=8tev.
Creator: Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M...
Show moreSirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schieck, J., Strauss, J., Waltenberger, W., Wulz, C.-E., Dvornikov, O., Makarenko, V., Mossolov, V., Gonzalez, J. Suarez, Zykunov, V., Shumeiko, N., Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., Van De Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, F., D'Hondt, J., Daci, N., De Bruyn, I., Deroover, K., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Skovpen, K., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Leonard, A., Luetic, J., Maerschalk, T., Marinov, A., Randle-Conde, A., Seva, T., Velde, C. Vander, Vanlaer, P., Vannerom, D., Yonamine, R., Zenoni, F., Zhang, F., Cimmino, A., Cornelis, T., Dobur, D., Fagot, A., Gul, M., Khvastunov, I., Poyraz, D., Silva, S., Schofbeck, R., Tytgat, M., Van Driessche, W., Yazgan, E., Zaganidis, N., Bakhshiansohi, H., Beluffi, C., Bondu, O., Brochet, S., Bruno, G., Caudron, A., De Visscher, S., Delaere, C., Delcourt, M., Francois, B., Giammanco, A., Jafari, A., Komm, M., Krintiras, G., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Piotrzkovvski, K., Quertenmont, L., Selvaggi, M., Marono, M. Vidal, Wertz, S., Beliy, N., Alda Junior, W. L., Alves, F. L., Alves, G. A., Brito, L., Hensel, C., Moraes, A., Pol, M. E., Rebell Teles, P., Belchior Batista Das Chagas, E., Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Huertas Guativa, L. M., Malbouisson, H., Matos Figueiredo, D., Mora Herrera, C., Mundim, L., Nogima, H., Prado Da Silva, W. L., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Torres Da Silva De Araujo, F., Vilela Pereira, A., Ahuja, S., Bernardes, C. A., Dogra, S., Fernandez Perez Tomei, T. R., Gregores, E. M., Mercadante, P. G., Moon, C. S., Novaes, S. F., Padula, Sandra S., Romero Abad, D., Ruiz Vargas, J. C., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Rodozov, M., Stoykova, S., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Litov, L., Pavlov, B., Petkov, P., Fang, W., Ahmad, M., Bian, J. G., Chen, G. M., Chen, H. S., Chen, M., Chen, Y., Cheng, T., Jiang, C. H., Leggat, D., Liu, Z., Romeo, F., Ruan, M., Shaheen, S. M., Spiezia, A., Tao, J., Wang, C., Wang, Z., Zhang, H., Zhao, J., Ban, Y., Chen, G., Li, Q., Liu, S., Mao, Y., Qian, S. J., Wang, D., Xu, Z., Avila, C., Cabrera, A., Chaparro Sierra, L. E., Florez, C., Gomez, J. P., Gonzalez Hernandez, C. F., Ruiz Alvarez, J. D., Sanabria, J. C., Godinovic, N., Lelas, D., Puljak, I., Cipriano, P. M. 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R., Dreyer, T., Garutti, E., Gonzalez, D., Haller, J., Hoffmann, M., Junkes, A., Klanner, R., Kogler, R., Kovalchuk, N., Lapsien, T., Marchesini, I., Marconi, D., Meyer, M., Niedziela, M., Nowatschin, D., Pantaleo, F., Peiffer, T., Perieanu, A., Scharf, C., Schleper, P., Schmidt, A., Schumann, S., Schwandt, J., Stadie, H., Steinbrueck, G., Stober, F. M., Stoever, M., Tholen, H., Troendle, D., Usai, E., Vanelderen, L., Vanhoefer, A., Vormwald, B., Akbiyik, M., Barth, C., Baur, S., Baus, C., Berger, J., Butz, F., Caspart, R., Chwalek, T., Colombo, F., De Boer, W., Dierlamm, A., Fink, S., Freund, B., Friese, R., Giffels, M., Gilbert, A., Goldenzweig, P., Haitz, D., Hartmann, F., Heindl, S. M., Husemann, U., Katkov, I., Kudella, S., Mildner, H., Mozer, M. U., Mueller, Th, Plagge, M., Quast, G., Rabbertz, K., Roecker, S., Roscher, F., Schroeder, M., Shveisov, I., Sieber, G., Simonis, H. J., Ulrich, R., Wayand, S., Weber, M., Weiler, T., Williamson, S., Woehrmann, C., Wolf, R., Anagnostou, G., Daskalakis, G., Geralis, T., Giakoumopoulou, V. A., Kyriakis, A., Loukas, D., Topsis-Giotis, I., Kesisoglou, S., Panagiotou, A., Saoulidou, N., Tziaferi, E., Evangelou, I., Flouris, G., Foudas, C., Kokkas, P., Loukas, N., Manthos, N., Papadopoulos, I., Paradas, E., Filipovic, N., Pasztor, G., Bencze, G., Hajdu, C., Horvath, D., Sikler, F., Veszpremi, V., Vesztergombi, G., Zsigmond, A. J., Beni, N., Czellar, S., Karancsi, J., Makovec, A., Molnar, J., Szillasi, Z., Bartok, M., Raics, P., Trocsanyi, Z. L., Ujvari, B., Komaragiri, J. R., Bahinipati, S., Bhowmik, S., Choudhury, S., Mal, P., Mandal, K., Nayak, A., Sahoo, D. K., Sahoo, N., Swain, S. K., Bansal, S., Beri, S. B., Bhatnagar, V., Chawla, R., Bhawandeep, U., Kalsi, A. K., Kaur, A., Kaur, M., Kumar, R., Kumari, P., Mehta, A., Mittal, M., Singh, J. B., Walia, G., Kumar, Ashok, Bhardwaj, A., Choudhary, B. C., Garg, R. B., Keshri, S., Malhotra, S., Naimuddin, M., Ranjan, K., Sharma, R., Sharma, V., Bhattacharya, R., Bhattacharya, S., Chatterjee, K., Dey, S., Dutt, S., Dutta, S., Ghosh, S., Majumdar, N., Modak, A., Mondal, K., Mukhopadhyay, S., Nandan, S., Purohit, A., Roy, A., Roy, D., Chowdhury, S. Roy, Sarkar, S., Sharan, M., Thakur, S., Behera, P. K., Chudasama, R., Dutta, D., Jha, V., Kumar, V., Mohanty, A. K., Netrakanti, P. K., Pant, L. M., Shukla, P., Topkar, A., Aziz, T., Dugad, S., Kole, G., Mahakud, B., Mitra, S., Mohanty, G. B., Parida, B., Sur, N., Sutar, B., Banerjee, S., Dewanjee, R. K., Ganguly, S., Guchait, M., Jain, Sa, Kumar, S., Maity, M., Majumder, G., Mazumdar, K., Sarkar, T., Wickramage, N., Chauhan, S., Dube, S., Hegde, V., Kapoor, A., Kothekar, K., Pandey, S., Rane, A., Sharma, S., Chenarani, S., Tadavani, E. Eskandari, Etesami, S. M., Khakzad, M., Najafabadi, M. Mohammadi, Naseri, M., Mehdiabadi, S. Paktinat, Hosseinabadi, F. 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Abstract/Description: The first measurement of the jet mass m(jet) of top quark jets produced in t (t) over bar events from pp collisions at root s = 8 TeV is reported for the jet with the largest transverse momentum p(T) in highly boosted hadronic top quark decays. The data sample, collected with the CMS detector, corresponds to an integrated luminosity of 19.7 fb(-1). The measurement is performed in the lepton+jets channel in which the products of the semileptonic decay t -> bW with W -> l nu where l is an...
Show moreThe first measurement of the jet mass m(jet) of top quark jets produced in t (t) over bar events from pp collisions at root s = 8 TeV is reported for the jet with the largest transverse momentum p(T) in highly boosted hadronic top quark decays. The data sample, collected with the CMS detector, corresponds to an integrated luminosity of 19.7 fb(-1). The measurement is performed in the lepton+jets channel in which the products of the semileptonic decay t -> bW with W -> l nu where l is an electron or muon, are used to select t (t) over bar events with large Lorentz boosts. The products of the fully hadronic decay t -> bW with W -> q (q) over bar ' are reconstructed using a single Cambridge-Aachen jet with distance parameter R = 1.2, and pT > 400 GeV. The t (t) over bar cross section as a function of m(jet) is unfolded at the particle level and is used to test the modelling of highly boosted top quark production. The peak position of the m(jet) distribution is sensitive to the top quark mass m(t), and the data are used to extract a value of m(t) to assess this sensitivity.
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Date Issued: 2017-07-14
Identifier: FSU_libsubv1_wos_000405437500001, 10.1140/epjc/s10052-017-5030-3
Format: Citation

Title: Defying Dissolution: Discovery Of Deep-sea Scleractinian Coral Reefs In The North Pacific.
Creator: Baco, Amy R., Morgan, Nicole, Roark, E. Brendan, Silva, Mauricio, Shamberger, Kathryn E. F., Miller, Kelci
Abstract/Description: Deep-sea scleractinian coral reefs are protected ecologically and biologically significant areas that support global fisheries. The absence of observations of deep-sea scleractinian reefs in the Central and Northeast Pacific, combined with the shallow aragonite saturation horizon (ASH) and high carbonate dissolution rates there, fueled the hypothesis that reef formation in the North Pacific was improbable. Despite this, we report the discovery of live scleractinian reefs on six seamounts of...
Show moreDeep-sea scleractinian coral reefs are protected ecologically and biologically significant areas that support global fisheries. The absence of observations of deep-sea scleractinian reefs in the Central and Northeast Pacific, combined with the shallow aragonite saturation horizon (ASH) and high carbonate dissolution rates there, fueled the hypothesis that reef formation in the North Pacific was improbable. Despite this, we report the discovery of live scleractinian reefs on six seamounts of the Northwestern Hawaiian Islands and Emperor Seamount Chain at depths of 535-732 m and aragonite saturation state (Omega(arag)) values of 0.71-1.33. Although the ASH becomes deeper moving northwest along the chains, the depth distribution of the reefs becomes shallower, suggesting the ASH is having little influence on their distribution. Higher chlorophyll moving to the northwest may partially explain the geographic distribution of the reefs. Principle Components Analysis suggests that currents are also an important factor in their distribution, but neither chlorophyll nor the available current data can explain the unexpected depth distribution. Further environmental data is needed to elucidate the reason for the distribution of these reefs. The discovery of reef-forming scleractinians in this region is of concern because a number of the sites occur on seamounts with active trawl fisheries.
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Date Issued: 2017-07-14
Identifier: FSU_libsubv1_wos_000405464200073, 10.1038/s41598-017-05492-w
Format: Citation

Title: Notes on operations: Using automation and batch processing to remediate duplicate series data in a shared bibliographic catalog.
Creator: Dong, Elaine, Glerum, Margaret Anne, Fenichel, Ethan
Abstract/Description: The application of divergent local practices in a shared bibliographic database can result in unexpected display issues that adversely affect user experience. This is especially problematic when merging databases from multiple institutions accustomed to adopting local practices for their own constituents. The authors describe their experience with the application of automation tools, such as MarcEdit, Excel, and Python, during a large-scale remediation project. They used these tools to...
Show moreThe application of divergent local practices in a shared bibliographic database can result in unexpected display issues that adversely affect user experience. This is especially problematic when merging databases from multiple institutions accustomed to adopting local practices for their own constituents. The authors describe their experience with the application of automation tools, such as MarcEdit, Excel, and Python, during a large-scale remediation project. They used these tools to analyze, compare, and batch process bibliographic records to remediate obsolete and redundant series data in their shared bibliographic database.
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Date Issued: 2017-07-14
Identifier: FSU_libsubv1_scholarship_submission_1500077579_786d99aa, 10.5860/lrts.61n3.143
Format: Citation

Title: Can Interface Cues Nudge Modeling of Food Consumption?: Experiments on a Food Ordering Website.
Creator: Hou, Jinghui
Abstract/Description: Following the nudging perspective, this research investigates how technology interface could cue heuristics that influence decisions. A field study showed that interface cues on a food ordering website signaling the amount of food other users consume could trigger an anchoring heuristic and induce individuals to model that amount when deciding their own consumption volume. A laboratory experiment further showed that the anchoring cue tends to induce the modeling behavior of individuals...
Show moreFollowing the nudging perspective, this research investigates how technology interface could cue heuristics that influence decisions. A field study showed that interface cues on a food ordering website signaling the amount of food other users consume could trigger an anchoring heuristic and induce individuals to model that amount when deciding their own consumption volume. A laboratory experiment further showed that the anchoring cue tends to induce the modeling behavior of individuals without them being aware of its influence, and such an influence was especially pronounced when resources for cognitive deliberation were limited. Altogether, this research suggests that interface cues could function as nudges and influence decisions at a relatively automatic level. Implications for technology design and intervention are discussed.
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Date Issued: 2017-07-13
Identifier: FSU_libsubv1_scholarship_submission_1508347466_19555ad6, 10.1111/jcc4.12190
Format: Citation

Title: Validation Of 10-year Sao Omi Ozone Profile (profoz) Product Using Ozonesonde Observations.
Creator: Huang, Guanyu, Liu, Xiong, Chance, Kelly, Yang, Kai, Bhartia, Pawan K., Cai, Zhaonan, Allaart, Marc, Ancellet, Gerard, Calpini, Bertrand, Coetzee, Gerrie J. R., Cuevas-Agullo,...
Show moreHuang, Guanyu, Liu, Xiong, Chance, Kelly, Yang, Kai, Bhartia, Pawan K., Cai, Zhaonan, Allaart, Marc, Ancellet, Gerard, Calpini, Bertrand, Coetzee, Gerrie J. R., Cuevas-Agullo, Emilio, Cupeiro, Manuel, De Backer, Hugo, Dubey, Manvendra K., Fuelberg, Henry E., Fujiwara, Masatomo, Godin-Beekmann, Sophie, Hall, Tristan J., Johnson, Bryan, Joseph, Everette, Kivi, Rigel, Kois, Bogumil, Komala, Ninong, Koenig-Langlo, Gert, Laneve, Giovanni, Leblanc, Thierry, Marchand, Marion, Minschwaner, Kenneth R., Morris, Gary, Newchurch, Michael J., Ogino, Shin-Ya, Ohkawara, Nozomu, Piters, Ankie J. M., Posny, Francoise, Querel, Richard, Scheele, Rinus, Schmidlin, Frank J., Schnell, Russell C., Schrems, Otto, Selkirk, Henry, Shiotani, Masato, Skrivankova, Pavla, Sutbi, Rene, Taha, Ghassan, Tarasick, David W., Thompson, Anne M., Thouret, Valerie, Tully, Matthew B., Van Malderen, Roeland, Vomel, Holger, von der Gathen, Peter, Witte, Jacquelyn C., Yela, Margarita
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Abstract/Description: We validate the Ozone Monitoring Instrument (OMI) Ozone Profile (PROFOZ) product from October 2004 through December 2014 retrieved by the Smithsonian Astrophysical Observatory (SAO) algorithm against ozonesonde observations. We also evaluate the effects of OMI row anomaly (RA) on the retrieval by dividing the dataset into before and after the occurrence of serious OMI RA, i.e., pre-RA (2004-2008) and post-RA (2009-2014). The retrieval shows good agreement with ozonesondes in the tropics and...
Show moreWe validate the Ozone Monitoring Instrument (OMI) Ozone Profile (PROFOZ) product from October 2004 through December 2014 retrieved by the Smithsonian Astrophysical Observatory (SAO) algorithm against ozonesonde observations. We also evaluate the effects of OMI row anomaly (RA) on the retrieval by dividing the dataset into before and after the occurrence of serious OMI RA, i.e., pre-RA (2004-2008) and post-RA (2009-2014). The retrieval shows good agreement with ozonesondes in the tropics and midlatitudes and for pressure < similar to 50 hPa in the high latitudes. It demonstrates clear improvement over the a priori down to the lower troposphere in the tropics and down to an average of similar to 550 (300) hPa at middle (high) latitudes. In the tropics and midlatitudes, the profile mean biases (MBs) are less than 6 %, and the standard deviations (SDs) range from 5 to 10% for pressure < similar to 50 hPa to less than 18% (27 %) in the tropics (midlatitudes) for pressure > similar to 50 hPa after applying OMI averaging kernels to ozonesonde data. The MBs of the stratospheric ozone column (SOC, the ozone column from the tropopause pressure to the ozonesonde burst pressure) are within 2% with SDs of < 5% and the MBs of the tropospheric ozone column (TOC) are within 6% with SDs of 15 %. In the high latitudes, the profile MBs are within 10% with SDs of 5-15% for pressure < similar to 50 hPa but increase to 30% with SDs as great as 40% for pressure > similar to 50 hPa. The SOC MBs increase up to 3% with SDs as great as 6% and the TOC SDs increase up to 30 %. The comparison generally degrades at larger solar zenith angles (SZA) due to weaker signals and additional sources of error, leading to worse performance at high latitudes and during the midlatitude winter. Agreement also degrades with increasing cloudiness for pressure > similar to 100 hPa and varies with cross-track position, especially with large MBs and SDs at extreme off-nadir positions. In the tropics and midlatitudes, the post-RA comparison is considerably worse with larger SDs reaching 2% in the stratosphere and 8% in the troposphere and up to 6% in TOC. There are systematic differences that vary with latitude compared to the pre-RA comparison. The retrieval comparison demonstrates good long-term stability during the pre-RA period but exhibits a statistically significant trend of 0.14-0.7% year 1 for pressure < similar to 80 hPa, 0.7DUyear(-1) in SOC, and 0 : 33DUyear(-1) in TOC during the post-RA period. The spatiotemporal variation of retrieval performance suggests the need to improve OMI's radiometric calibration especially during the post-RA period to maintain the long-term stability and reduce the latitude/season/SZA and cross-track dependency of retrieval quality.
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Date Issued: 2017-07-13
Identifier: FSU_libsubv1_wos_000405522800001, 10.5194/amt-10-2455-2017
Format: Citation

Title: Platelet Function Is Modified By Common Sequence Variation In Megakaryocyte Super Enhancers.
Creator: Petersen, Romina, Lambourne, John J., Javierre, Biola M., Grassi, Luigi, Kreuzhuber, Roman, Ruklisa, Dace, Rosa, Isabel M., Tome, Ana R., Elding, Heather, van Geffen, Johanna P....
Show morePetersen, Romina, Lambourne, John J., Javierre, Biola M., Grassi, Luigi, Kreuzhuber, Roman, Ruklisa, Dace, Rosa, Isabel M., Tome, Ana R., Elding, Heather, van Geffen, Johanna P., Jiang, Tao, Farrow, Samantha, Cairns, Jonathan, Al-Subaie, Abeer M., Ashford, Sofie, Attwood, Antony, Batista, Joana, Bouman, Heleen, Burden, Frances, Choudry, Fizzah A., Clarke, Laura, Flicek, Paul, Garner, Stephen F., Haimel, Matthias, Kempster, Carly, Ladopoulos, Vasileios, Lenaerts, An-Sofie, Materek, Paulina M., McKinney, Harriet, Meacham, Stuart, Mead, Daniel, Nagy, Magdolna, Penkett, Christopher J., Rendon, Augusto, Seyres, Denis, Sun, Benjamin, Tuna, Salih, van der Weide, Marie-Elise, Wingett, Steven W., Martens, Joost H., Stegle, Oliver, Richardson, Sylvia, Vallier, Ludovic, Roberts, David J., Freson, Kathleen, Wernisch, Lorenz, Stunnenberg, Hendrik G., Danesh, John, Fraser, Peter, Soranzo, Nicole, Butterworth, Adam S., Heemskerk, Johan W., Turro, Ernest, Spivakov, Mikhail, Ouwehand, Willem H., Astle, William J., Downes, Kate, Kostadima, Myrto, Frontini, Mattia
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Abstract/Description: Linking non-coding genetic variants associated with the risk of diseases or disease-relevant traits to target genes is a crucial step to realize GWAS potential in the introduction of precision medicine. Here we set out to determine the mechanisms underpinning variant association with platelet quantitative traits using cell type-matched epigenomic data and promoter long-range interactions. We identify potential regulatory functions for 423 of 565 (75%) non-coding variants associated with...
Show moreLinking non-coding genetic variants associated with the risk of diseases or disease-relevant traits to target genes is a crucial step to realize GWAS potential in the introduction of precision medicine. Here we set out to determine the mechanisms underpinning variant association with platelet quantitative traits using cell type-matched epigenomic data and promoter long-range interactions. We identify potential regulatory functions for 423 of 565 (75%) non-coding variants associated with platelet traits and we demonstrate, through ex vivo and proof of principle genome editing validation, that variants in super enhancers play an important role in controlling archetypical platelet functions.
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Date Issued: 2017-07-13
Identifier: FSU_libsubv1_wos_000405401600001, 10.1038/ncomms16058
Format: Citation

Title: How Novices Perceive the Culture of Physics.
Creator: Bremer, Martin, Hughes, Roxanne
Abstract/Description: This study is an exploratory qualitative research project utilizing deductive thematic analysis to investigate how undergraduate physics students form their physics identity. Physics is a unique community of practice that has lagged behind other science fields in terms of the representation of women and members of underrepresented minority groups. This underrepresentation within physics is often credited to the culture of physics which makes identity studies within this specific field that...
Show moreThis study is an exploratory qualitative research project utilizing deductive thematic analysis to investigate how undergraduate physics students form their physics identity. Physics is a unique community of practice that has lagged behind other science fields in terms of the representation of women and members of underrepresented minority groups. This underrepresentation within physics is often credited to the culture of physics which makes identity studies within this specific field that much more important – understanding who persists and why they persist in terms of their identification with physics will help physics departments determine how they can better attract and retain students from underrepresented groups. In this study we used individual interview data with 44 undergraduate physics majors at a Research I university. Our study indicates that novices within physics see the culture of physics as filled with smart, curious, people who are committed to physics as a subject matter and see it as the basis for all science. As part of this culture these novices saw arrogance as a definitive trait for a strong physics identity. Women who left the major mentioned the culture (arrogance) as one of the main factors for their decision to leave. This study indicates that younger generations of women are still facing the same issues as past generations of women in physics. Future studies should investigate the differences between the discipline cultures that may be affecting the improvement of women and underrepresented minorities in specific STEM fields, thereby tailoring programs and policies to the unique culture within each discipline.
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Date Issued: 2017-07-13
Identifier: FSU_libsubv1_scholarship_submission_1500467064_f4144f0f, 10.1615/JWomenMinorScienEng.2017016953
Format: Citation

Title: Nutrient Sensing: Another Chemosensitivity Of The Olfactory System.
Creator: Julliard, A.-Karyn, Al Koborssy, Dolly, Fadool, Debra A., Palouzier-Paulignan, Brigitte
Abstract/Description: Olfaction is a major sensory modality involved in real time perception of the chemical composition of the external environment. Olfaction favors anticipation and rapid adaptation of behavioral responses necessary for animal survival. Furthermore, recent studies have demonstrated that there is a direct action of metabolic peptides on the olfactory network. Orexigenic peptides such as ghrelin and orexin increase olfactory sensitivity, which in turn, is decreased by anorexigenic hormones such as...
Show moreOlfaction is a major sensory modality involved in real time perception of the chemical composition of the external environment. Olfaction favors anticipation and rapid adaptation of behavioral responses necessary for animal survival. Furthermore, recent studies have demonstrated that there is a direct action of metabolic peptides on the olfactory network. Orexigenic peptides such as ghrelin and orexin increase olfactory sensitivity, which in turn, is decreased by anorexigenic hormones such as insulin and leptin. In addition to peptides, nutrients can play a key role on neuronal activity. Very little is known about nutrient sensing in olfactory areas. Nutrients, such as carbohydrates, amino acids, and lipids, could play a key role in modulating olfactory sensitivity to adjust feeding behavior according to metabolic need. Here we summarize recent findings on nutrient-sensing neurons in olfactory areas and delineate the limits of our knowledge on this topic. The present review opens new lines of investigations on the relationship between olfaction and food intake, which could contribute to determining the etiology of metabolic disorders.
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Date Issued: 2017-07-12
Identifier: FSU_libsubv1_wos_000405365400001, 10.3389/fphys.2017.00468
Format: Citation

Title: Proteomic Characterization Of Paired Non-malignant And Malignant African-american Prostate Epithelial Cell Lines Distinguishes Them By Structural Proteins.
Creator: Myers, Jennifer S., Vallega, Karin A., White, Jason, Yu, Kaixian, Yates, Clayton C., Sang, Qing-Xiang Amy
Abstract/Description: Background: While many factors may contribute to the higher prostate cancer incidence and mortality experienced by African-American men compared to their counterparts, the contribution of tumor biology is underexplored due to inadequate availability of African-American patient-derived cell lines and specimens. Here, we characterize the proteomes of non-malignant RC-77 N/E and malignant RC-77 T/E prostate epithelial cell lines previously established from prostate specimens from the same...
Show moreBackground: While many factors may contribute to the higher prostate cancer incidence and mortality experienced by African-American men compared to their counterparts, the contribution of tumor biology is underexplored due to inadequate availability of African-American patient-derived cell lines and specimens. Here, we characterize the proteomes of non-malignant RC-77 N/E and malignant RC-77 T/E prostate epithelial cell lines previously established from prostate specimens from the same African-American patient with early stage primary prostate cancer. Methods: In this comparative proteomic analysis of RC-77 N/E and RC-77 T/E cells, differentially expressed proteins were identified and analyzed for overrepresentation of PANTHER protein classes, Gene Ontology annotations, and pathways. The enrichment of gene sets and pathway significance were assessed using Gene Set Enrichment Analysis and Signaling Pathway Impact Analysis, respectively. The gene and protein expression data of age- and stage-matched prostate cancer specimens from The Cancer Genome Atlas were analyzed. Results: Structural and cytoskeletal proteins were differentially expressed and statistically overrepresented between RC-77 N/E and RC-77 T/E cells. Beta-catenin, alpha-actinin-1, and filamin-A were upregulated in the tumorigenic RC-77 T/E cells, while integrin beta-1, integrin alpha-6, caveolin-1, laminin subunit gamma-2, and CD44 antigen were downregulated. The increased protein level of beta-catenin and the reduction of caveolin-1 protein level in the tumorigenic RC-77 T/E cells mirrored the upregulation of beta-catenin mRNA and downregulation of caveolin-1 mRNA in African-American prostate cancer specimens compared to non-malignant controls. After subtracting race-specific non-malignant RNA expression, beta-catenin and caveolin-1 mRNA expression levels were higher in African-American prostate cancer specimens than in Caucasian-American specimens. The "ECM-Receptor Interaction" and "Cell Adhesion Molecules", and the "Tight Junction" and "Adherens Junction" pathways contained proteins are associated with RC-77 N/E and RC-77 T/E cells, respectively. Conclusions: Our results suggest RC-77 T/E and RC-77 N/E cell lines can be distinguished by differentially expressed structural and cytoskeletal proteins, which appeared in several pathways across multiple analyses. Our results indicate that the expression of beta-catenin and caveolin-1 may be prostate cancer- and race-specific. Although the RC-77 cell model may not be representative of all African-American prostate cancer due to tumor heterogeneity, it is a unique resource for studying prostate cancer initiation and progression.
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Date Issued: 2017-07-11
Identifier: FSU_libsubv1_wos_000405352400004, 10.1186/s12885-017-3462-7
Format: Citation

Title: Measurement Of Double-differential Cross Sections For Top Quark Pair Production In Pp Collisions At Root S=8 Tev And Impact On Parton Distribution Functions.
Creator: Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M...
Show moreSirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schieck, J., Strauss, J., Waltenberger, W., Wulz, C.-E., Dvornikov, O., Makarenko, V., Mossolov, V., Gonzalez, J. Suarez, Zykunov, V., Shumeiko, N., Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., Van De Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, F., D'Hondt, J., Daci, N., De Bruyn, I., Deroover, K., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Skovpen, K., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Leonard, A., Luetic, J., Maerschalk, T., Marinov, A., Randle-Conde, A., Seva, T., Vander Velde, C., Vanlaer, P., Vannerom, D., Yonamine, R., Zenoni, F., Zhang, F., Cornelis, T., Dobur, D., Fagot, A., Gul, M., Khvastunov, I., Poyraz, D., Salva, S., Schofbeck, R., Tytgat, M., Van Driessche, W., Yazgan, E., Zaganidis, N., Bakhshiansohi, H., Bondu, O., Brochet, S., Bruno, G., Caudron, A., De Visscher, S., Delaere, C., Delcourt, M., Francois, B., Giammanco, A., Jafari, A., Komm, M., Krintiras, G., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Piotrzkowski, K., Quertenmont, L., Selvaggi, M., Marono, M. Vidal, Wertz, S., Beliy, N., Alda Junior, W. L., Alves, F. L., Alves, G. A., Brito, L., Hensel, C., Moraes, A., Pol, M. E., Rebello Teles, P., Belchior Batista Das Chagas, E., Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Huertas Guativa, L. M., Malbouisson, H., Matos Figueiredo, D., Mora Herrera, C., Mundim, L., Nogima, H., Prado Da Silva, W. L., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Torres Da Silva De Araujo, F., Vilela Pereira, A., Ahuja, S., Bernardes, C. A., Dogra, S., Fernandez Perez Tomei, T. R., Gregores, E. M., Mercadante, P. G., Moon, C. S., Novaes, S. F., Padula, Sandra S., Romero Abad, D., Ruiz Vargas, J. C., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Rodozov, M., Stoykova, S., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Litov, L., Pavlov, B., Petkov, P., Fang, W., Ahmad, M., Bian, J. G., Chen, G. M., Chen, H. S., Chen, M., Chen, Y., Cheng, T., Jiang, C. H., Leggat, D., Liu, Z., Romeo, F., Ruan, M., Shaheen, S. M., Spiezia, A., Tao, J., Wang, C., Wang, Z., Zhang, H., Zhao, J., Ban, Y., Chen, G., Li, Q., Liu, S., Mao, Y., Qian, S. J., Wang, D., Xu, Z., Avila, C., Cabrera, A., Chaparro Sierra, L. F., Florez, C., Gomez, J. P., Gonzalez Hernandez, C. F., Ruiz Alvarez, J. D., Sanabria, J. C., Godinovic, N., Lelas, D., Puljak, I., Cipriano, P. M. Ribeiro, Sculac, T., Antunovic, Z., Kovac, M., Brigljevic, V., Ferencek, D., Kadija, K., Mesic, B., Susa, T., Ather, M. W., Attikis, A., Mavromanolakis, G., Mousa, J., Nicolaou, C., Ptochos, F., Razis, P. A., Rykaczewski, H., Finger, M., Finger, M., Carrera Jarrin, E., Kamel, A. Ellithi, Mahmoud, M. A., Radi, A., Kadastik, M., Perrini, L., Raidal, M., Tiko, A., Veelken, C., Eerola, P., Pekkanen, J., Voutilainen, M., Harkonen, J., Jarvinen, T., Karimaki, V., Kinnunen, R., Lampen, T., Lassila-Perini, K., Lehti, S., Linden, T., Luukka, P., Tuominiemi, J., Tuovinen, E., Wendland, L., Talvitie, J., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Fabbro, B., Faure, J. L., Favaro, C., Ferri, F., Ganjour, S., Ghosh, S., Givernaud, A., Gras, P., de Monchenault, G. Hamel, Jarry, P., Kucher, I., Locci, E., Machet, M., Malcles, J., Rander, J., Rosowsky, A., Titov, M., Abdulsalam, A., Antropov, I., Baffioni, S., Beaudette, F., Busson, P., Cadamuro, L., Chapon, E., Charlot, C., Davignon, O., de Cassagnac, R. Granier, Jo, M., Lisniak, S., Mine, P., Nguyen, M., Ochando, C., Ortona, G., Paganini, P., Pigard, P., Regnard, S., Salerno, R., Sirois, Y., Leiton, A. G. Stahl, Strebler, T., Yilmaz, Y., Zabi, A., Zghiche, A., Agram, J.-L., Andrea, J., Bloch, D., Brom, J.-M., Buttignol, M., Chabert, E. C., Chanon, N., Collard, C., Conte, E., Coubez, X., Fontaine, J.-C., Gele, D., Goerlach, U., Le Bihan, A.-C., Van Hove, P., Gadrat, S., Beauceron, S., Bernet, C., Boudoul, G., Montoya, C. A. Carrillo, Chierici, R., Contardo, D., Courbon, B., Depasse, P., El Mamouni, H., Fay, J., Finco, L., Gascon, S., Gouzevitch, M., Grenier, G., Ille, B., Lagarde, F., Laktineh, I. B., Lethuillier, M., Mirabito, L., Pequegnot, A. L., Perries, S., Popov, A., Sordini, V., Donckt, M. Vander, Verdier, P., Viret, S., Khvedelidze, A., Lomidze, D., Autermann, C., Beranek, S., Feld, L., Kiesel, M. K., Klein, K., Lipinski, M., Preuten, M., Schomakers, C., Schulz, J., Verlage, T., Albert, A., Brodski, M., Dietz-Laursonn, E., Duchardt, D., Endres, M., Erdmann, M., Erdweg, S., Esch, T., Fischer, R., Guth, A., Hamer, M., Hebbeker, T., Heidemann, C., Hoepfner, K., Knutzen, S., Merschmeyer, M., Meyer, A., Millet, P., Mukherjee, S., Olschewski, M., Padeken, K., Pook, T., Radziej, M., Reithler, H., Rieger, M., Scheuch, F., Sonnenschein, L., Teyssier, D., Thueer, S., Cherepanov, V., Flugge, G., Kargoll, B., Kress, T., Kuesken, A., Lingemann, J., Mueller, T., Nehrkorn, A., Nowack, A., Pistone, C., Pooth, O., Stahl, A., Martin, M. Aldaya, Arndt, T., Asawatangtrakuldee, C., Beernaert, K., Behnke, O., Behrens, U., Bin Anuar, A. A., Borras, K., Campbell, A., Connor, P., Contreras-Campana, C., Costanza, F., Pardos, C. Diez, Dolinska, G., Eckerlin, G., Eckstein, D., Eichhorn, T., Eren, E., Gallo, E., Garcia, J. Garay, Geiser, A., Gizhko, A., Luyando, J. M. Grados, Grohsjean, A., Gunnellini, P., Harb, A., Hauk, J., Hempel, M., Jung, H., Kalogeropoulos, A., Karacheban, O., Kasemann, M., Keaveney, J., Kleinwort, C., Korol, I., Kruecker, D., Lange, W., Lelek, A., Lenz, T., Leonard, J., Lipka, K., Lobanov, A., Lohmann, W., Mankel, R., Melzer-Pellmann, I.-A., Meyer, A. B., Mittag, G., Mnich, J., Mussgiller, A., Pitzl, D., Placakyte, R., Raspereza, A., Roland, B., Sahin, M. Oe, Saxena, P., Schoerner-Sadenius, T., Spannagel, S., Stefaniuk, N., Van Onsem, G. P., Walsh, R., Wissing, C., Zenaiev, O., Blobel, V., Vignali, M. Centis, Draeger, A. R., Dreyer, T., Garutti, E., Gonzalez, D., Haller, J., Hoffmann, M., Junkes, A., Klanner, R., Kogler, R., Kovalchuk, N., Kurz, S., Lapsien, T., Marchesini, I., Marconi, D., Meyer, M., Niedziela, M., Nowatschin, D., Pantaleo, F., Peiffer, T., Perieanu, A., Scharf, C., Schleper, P., Schmidt, A., Schumann, S., Schwandt, J., Sonneveld, J., Stadie, H., Steinbruek, G., Stober, F. M., Stoever, M., Tholen, H., Troendle, D., Usai, E., Vanelderen, L., Vanhoefer, A., Vormwald, B., Akbiyik, M., Barth, C., Baur, S., Baus, C., Berger, J., Butz, E., Caspart, R., Chwalek, T., Colombo, F., De Boer, W., Dierlamm, A., Fink, S., Freund, B., Friese, R., Giffels, M., Gilbert, A., Goldenzweig, P., Haitz, D., Hartmann, F., Heindl, S. M., Husemann, U., Kassel, F., Katkov, I., Kudella, S., Mildner, H., Mozer, M. U., Mueller, Th, Plagge, M., Quast, G., Rabbertz, K., Roecker, S., Roscher, F., Schroeder, M., Shvetsov, I., Sieber, G., Simonis, H. J., Ulrich, R., Wayand, S., Weber, M., Weiler, T., Williamson, S., WHrmann, C., Wolf, R., Anagnostou, G., Daskalakis, G., Geralis, T., Giakoumopoulou, V. 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Abstract/Description: Normalized double-differential cross sections for top quark pair (t (t) over bar) production are measured in pp collisions at a centre-of-mass energy of 8 TeV with the CMS experiment at the LHC. The analyzed data correspond to an integrated luminosity of 19.7 fb(-1). The measurement is performed in the dilepton e(+/-)mu(+/-) final state. The tt cross section is determined as a function of various pairs of observables characterizing the kinematics of the top quark and tt system. The data are...
Show moreNormalized double-differential cross sections for top quark pair (t (t) over bar) production are measured in pp collisions at a centre-of-mass energy of 8 TeV with the CMS experiment at the LHC. The analyzed data correspond to an integrated luminosity of 19.7 fb(-1). The measurement is performed in the dilepton e(+/-)mu(+/-) final state. The tt cross section is determined as a function of various pairs of observables characterizing the kinematics of the top quark and tt system. The data are compared to calculations using perturbative quantum chromodynamics at next-to-leading and approximate next-to-next-to-leading orders. They are also compared to predictions of Monte Carlo event generators that complement fixed-order computations with parton showers, hadronization, and multiple-parton interactions. Overall agreement is observed with the predictions, which is improved when the latest global sets of proton parton distribution functions are used. The inclusion of the measured tt cross sections in a fit of parametrized parton distribution functions is shown to have significant impact on the gluon distribution.
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Date Issued: 2017-07-11
Identifier: FSU_libsubv1_wos_000405244200001, 10.1140/epjc/s10052-017-4984-5
Format: Citation

Title: Measurement Of The Cross Section For Electroweak Production Of Z Gamma In Association With Two Jets And Constraints On Anomalous Quartic Gauge Couplings In Proton-proton Collisions At Root S=8 Tev.
Creator: Khachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth...
Show moreKhachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schieck, J., Strauss, J., Treberer-Treberspurg, W., Waltenberger, W., Wulz, C.-E., Mossolov, V., Shumeiko, N., Gonzalez, J. Suarez, Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., Van De Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, E., D'Hondt, J., Daci, N., De Bruyn, I., Deroover, K., Heracleous, N., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Caillol, C., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Leonard, A., Luetic, J., Maerschalk, T., Marinov, A., Randle-Conde, A., Seva, T., Vander Velde, C., Vanlaer, P., Yonamine, R., Zenoni, F., Zhang, F., Cimmino, A., Cornelis, T., Dobur, D., Fagot, A., Garcia, G., Gul, M., Poyraz, D., Salva, S., Schofbeck, R., Tytgat, M., Van Driessche, W., Yazgan, E., Zaganidis, N., Beluffi, C., Bondu, O., Brochet, S., Bruno, G., Caudron, A., Ceard, L., De Visscher, S., Delaere, C., Delcourt, M., Forthomme, L., Francois, B., Giammanco, A., Jafari, A., Jez, P., Komm, M., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Nuttens, C., Piotrzkowski, K., Quertenmont, L., Selvaggi, M., Marono, M. Vidal, Wertz, S., Beliy, N., Alda Junior, W. L., Alves, F. L., Alves, G. A., Brito, L., Hensel, C., Moraes, A., Pol, M. E., Rebello Teles, P., Beichior Batista Das Chagas, E., Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Huertas Guativa, L. M., Malbouisson, H., Matos Figueiredo, D., Mora Herrera, C., Mundim, L., Nogima, H., Prado Da Silva, W. L., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Vilela Pereira, A., Ahuja, S., Bernardes, C. A., Dogra, S., Fernandez Perez Tomei, T. R., Gregores, E. M., Mercadante, P. G., Moon, C. S., Novaes, S. F., Padula, Sandra S., Romero Abad, D., Ruiz Vargas, J. C., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Rodozov, M., Stoykova, S., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Litov, L., Pavlov, B., Petkov, P., Fang, W., Ahmad, M., Bian, J. G., Chen, G. M., Chen, H. S., Chen, M., Chen, Y., Cheng, T., Jiang, C. 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Carrera, Elgamma, S., Mohamed, A., Mohammed, Y., Salama, E., Calpas, B., Kadastik, M., Murumaa, M., Perrini, L., Raidal, M., Tiko, A., Veelken, C., Eerola, P., Pekkanen, J., Voutilainen, M., Harkonen, J., Karimaki, V., Kinnunen, R., Lampen, T., Lassila-Perini, K., Lehti, S., Linden, T., Luukka, P., Peltola, T., Tuominiemi, J., Tuovinen, E., Wendland, L., Talvitie, J., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Fabbro, B., Faure, J. L., Favaro, C., Ferri, F., Ganjour, S., Ghosh, S., Givernaud, A., Gras, P., de Monchenault, G. Hamel, Jarry, P., Kucher, I., Locci, E., Machet, M., Malcles, J., Rander, J., Rosowsky, A., Titov, M., Zghiche, A., Abdulsalam, A., Antropov, I., Baffioni, S., Beaudette, F., Busson, P., Cadamuro, L., Chapon, E., Chariot, C., Davignon, O., de Cassagnac, R. Granier, Jo, M., Lisniak, S., Mine, P., Naranjo, I. N., Nguyen, M., Ochando, C., Ortona, G., Paganini, P., Pigard, P., Regnard, S., Salerno, R., Sirois, Y., Strebier, T., Yilmaz, Y., Zabi, A., Agram, J.-L., Andrea, J., Aubin, A., Bloch, D., Brom, J.-M., Buttignol, M., Chabert, E. C., Chanon, N., Collard, C., Conte, E., Coubez, X., Fontaine, J.-C., Gele, D., Goerlach, U., Le Bihan, A.-C., Merlin, J. A., Skovpen, K., Van Hove, P., Gadrat, S., Beauceron, S., Bernet, C., Boudoul, G., Bouvier, E., Montoya, C. A. Carrillo, Chierici, R., Contardo, D., Courbon, B., Depasse, P., El Mamouni, H., Fan, J., Fay, J., Gascon, S., Gouzevitch, M., Grenier, G., Ille, B., Lagarde, F., Laktineh, I. B., Lethuillier, M., Mirabito, L., Pequegnot, A. L., Perries, S., Popov, A., Sabes, D., Sordini, V., Vander Donckt, M., Verdier, P., Viret, S., Khvedelidze, A., Bagaturia, I., Autermann, C., Beranek, S., Feld, L., Heister, A., Kiesel, M. K., Klein, K., Lipinski, M., Ostapchuk, A., Preuten, M., Raupach, F., Schael, S., Schomakers, C., Schulte, J. 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Abstract/Description: A measurement is presented of the cross section for the electroweak production of a Z boson and a photon in association with two jets in proton-proton collisions at root s = 8 TeV. The Z bosons are identified through their decays to electron or muon pairs. The measurement is based on data collected with the CMS detector corresponding to an integrated luminosity of 19.7 fb(-1). The electroweak contribution has a significance of 3.0 standard deviations, and the measured fiducial cross section...
Show moreA measurement is presented of the cross section for the electroweak production of a Z boson and a photon in association with two jets in proton-proton collisions at root s = 8 TeV. The Z bosons are identified through their decays to electron or muon pairs. The measurement is based on data collected with the CMS detector corresponding to an integrated luminosity of 19.7 fb(-1). The electroweak contribution has a significance of 3.0 standard deviations, and the measured fiducial cross section is 1.86(-0.75)(+0.90)(stat)(-0.26)(+0.34)(syst) +/- 0.05(lumi) fb, while the summed electroweak and quantum chromodynamic total cross section in the same region is observed to be 5.94(-1.35)(+1.53) (stat)(-0.37)(+0.43)(syst) +/- 0.13(lumi) fb. Both measurements are consistent with the leading-order standard model predictions. Limits on anomalous quartic gauge couplings are set based on the Z gamma mass distribution. (C) 2017 The Author. Published by Elsevier B.V.
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Date Issued: 2017-07-10
Identifier: FSU_libsubv1_wos_000404196500051, 10.1016/j.physletb.2017.04.071
Format: Citation

Title: Suppression Of Gamma(1s), Gamma(2s), And Gamma(3s) Quarkonium States In Pbpb Collisions At Root S-nn=2.76tev.
Creator: Khachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth...
Show moreKhachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schieck, J., Strauss, J., Waltenberger, W., Wulz, C.-E., Dvornikov, O., Makarenko, V., Zykunov, V., Mossolov, V., Shumeiko, N., Gonzalez, J. Suarez, Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., Van De Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, F., D'Hondt, J., Daci, N., De Bruyn, I., Deroover, K., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Leonard, A., Luetic, J., Maerschalk, T., Marinov, A., Randle-Conde, A., Seva, T., Vander Velde, C., Vanlaer, P., Vannerom, D., Yonamine, R., Zenoni, F., Zhang, F., Cimmino, A., Cornelis, T., Dobur, D., Fagot, A., Garcia, G., Gul, M., Khvastunov, I., Poyraz, D., Salva, S., Schofbeck, R., Sharma, A., Tytgat, M., Van Driessche, W., Yazgan, E., Zaganidis, N., Bakhshiansohi, H., Beluffi, C., Bondu, O., Brochet, S., Bruno, G., Caudron, A., De Visscher, S., Delaere, C., Delcourt, M., Francois, B., Giammanco, A., Jafari, A., Jez, P., Komm, M., Krintiras, G., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Nuttens, C., Piotrzkowski, K., Quertenmont, L., Selvaggi, M., Marono, M. 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A., Buchanan, J., Caillol, C., Dasu, S., Dodd, L., Duric, S., Gomber, B., Grothe, M., Herndon, M., Herve, A., Klabbers, P., Lanaro, A., Levine, A., Long, K., Loveless, R., Ojalvo, I., Perry, T., Pierro, G. A., Polese, G., Ruggles, T., Savin, A., Smith, N., Smith, W. H., Taylor, D., Woods, N.
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Abstract/Description: The production yields of gamma(1S), gamma(2S), and gamma(3S) quarkonium states are measured through their decays into muon pairs in the CMS detector, in PbPb and pp collisions at the centre-of-mass energy per nucleon pair of 2.76TeV. The data correspond to integrated luminosities of 166 mu b(-1) and 5.4 pb(-1) for PbPb and pp collisions, respectively. Differential production cross sections are reported as functions of gamma rapidity y up to 2.4, and transverse momentum PT up to 20 GeV/c. A...
Show moreThe production yields of gamma(1S), gamma(2S), and gamma(3S) quarkonium states are measured through their decays into muon pairs in the CMS detector, in PbPb and pp collisions at the centre-of-mass energy per nucleon pair of 2.76TeV. The data correspond to integrated luminosities of 166 mu b(-1) and 5.4 pb(-1) for PbPb and pp collisions, respectively. Differential production cross sections are reported as functions of gamma rapidity y up to 2.4, and transverse momentum PT up to 20 GeV/c. A strong centrality-dependent suppression is observed in PbPb relative to pp collisions, by factors of up to approximate to 2 and 8, for the gamma(1S) and gamma(2S) states, respectively. No significant dependence of this suppression is observed as a function of y or PT. The gamma(3S) state is not observed in PbPb collisions, which corresponds to a suppression for the centrality-integrated data by at least a factor of approximate to 7 at a 95% confidence level. The observed suppression is in agreement with theoretical scenarios modeling the sequential melting of quarkonium states in a quark gluon plasma. (C) 2017 The Author(s). Published by Elsevier B.V.
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Date Issued: 2017-07-10
Identifier: FSU_libsubv1_wos_000404196500050, 10.1016/j.physletb.2017.04.031
Format: Citation

Title: Measurement Of The Mass Difference Between Top Quark And Antiquark In Pp Collisions At Root S=8 Tev.
Creator: Chatrchyan, S., Khachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Bergauer, T., Dragicevic, M., Eroe, J., Fabjan, C., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C....
Show moreChatrchyan, S., Khachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Bergauer, T., Dragicevic, M., Eroe, J., Fabjan, C., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Kiesenhofer, W., Knuenz, V., Krammer, M., Kraetschmer, I., Lilco, D., Mikulec, I., Rabady, D., Rahbaran, B., Rohringer, H., Schoefbeck, R., Strauss, J., Taurok, Treberer-Treberspurg, W., Waltenberger, W., Wulz, C.-E., Mossolov, V., Shumeiko, N., Gonzalez, J. Suarez, Alderweireldt, S., Bansal, M., Bansal, S., Cornelis, T., De Wolf, E. A., Janssen, X., Knutsson, A., Luyckx, S., Mucibello, L., Ochesanu, S., Roland, B., Rougny, R., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Blekman, F., Blyweert, S., D'Hondt, J., Heracleous, N., Kalogeropoulos, A., Keaveney, J., Kim, T. J., Lowette, S., Maes, M., Olbrechts, A., Strom, D., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Onsem, G. P., Villella, I., Caillol, C., Clerbaux, B., De Lentdecker, G., Favart, L., Gay, A. P. R., Hreus, T., Leonard, A., Marage, P. E., Mohammadi, A., Pernie, L., Reis, T., Seva, T., Thomas, L., Vander Velde, C., Vanlaer, P., Wang, J., Adler, V., Beernaert, K., Benucci, L., Cimmino, A., Costantini, S., Dildick, S., Garcia, G., Klein, B., Lellouch, J., Mccartin, J., Rios, A. A. Ocampo, Ryckbosch, D., Sigamani, M., Strobbe, N., Thyssen, F., Tytgat, M., Walsh, S., Yazgan, E., Zaganidis, N., Basegmez, S., Beluffi, C., Bruno, G., Castello, R., Caudron, A., Ceard, L., Da Silveira, G. G., Delaere, C., du Pree, T., Favart, D., Forthomme, L., Giammanco, A., Hollar, J., Jez, P., Komm, M., Lemaitre, V., Liao, J., Militaru, O., Nuttens, C., Pagano, D., Pin, A., Piotrzkowski, K., Popov, A., Quertenmont, L., Selvaggi, M., Marono, M. Vidal, Garcia, J. M. Vizan, Beliy, N., Caebergs, T., Daubie, E., Hammad, G. H., Alves, G. A., Correa Martins Junior, M., Martins, T. Dos Reis, Pol, M. E., Souza, M. H. G., Alda Junior, W. L., Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Malbouisson, H., Malek, M., Matos Figueiredo, D., Mundim, L., Nogima, H., Prado Da Silva, W. L., Santaolalla, J., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Vilela Pereira, A., Bernardes, C. A., Dias, F. A., Fernandez Perez Tomei, T. R., Gregores, E. M., Lagana, C., Mercadante, P. G., Novaes, S. F., Padula, Sandra S., Genchev, V., Iaydjiev, P., Marinov, A., Piperov, S., Rodozov, M., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Hadjiiska, R., Kozhuharov, V., Litov, L., Pavlov, B., Petkov, P., Bian, J. G., Chen, G. M., Chen, H. S., Chen, M., Du, R., Jiang, C. H., Liang, D., Liang, S., Meng, X., Plestina, R., Tao, J., Wang, X., Wang, Z., Asawatangtrakuldee, C., Ban, Y., Guo, Y., Li, Q., Li, W., Liu, S., Mao, Y., Qian, S. J., Wang, D., Zhang, L., Zou, W., Avila, C., Montoya, C. A. Carrillo, Sierra, L. F. Chaparro, Florez, C., Gomez, J. P., Moreno, B. Gomez, Sanabria, J. C., Godinovic, N., Lelas, D., Polic, D., Puijak, I., Antunovic, Z., Kovac, M., Brigljevic, V., Kadija, K., Luetic, J., Mekterovic, D., Morovic, S., Sudic, L., Attikis, A., Mavromanolakis, G., Mousa, J., Nicolaou, C., Ptochos, F., Razis, P. A., Finger, M., Finger, M., El-Khateeb, E., Elkafrawy, T., Mahmoud, M. A., Mohamed, A., Radi, A., Salama, E., Kadastik, M., Muentel, M., Murumaa, M., Raidal, M., Rebane, L., Tiko, A., Eerola, P., Fedi, G., Voutilainen, M., Harkonen, J., Karimaki, V., Kinnunen, R., Kortelainen, M. J., Lampen, T., Lassila-Perini, K., Lehti, S., Linden, T., Luukka, P., Maenpaa, T., Peltola, T., Tuominen, E., Tuominiemi, J., Tuovinen, E., Wendland, L., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Fabbro, B., Faure, J. L., Ferri, F., Ganjour, S., Givernaud, A., Gras, P., de Monchenault, G. Hamel, Jarry, P., Locci, E., Malcles, J., Nayak, A., Rander, J., Rosowsky, A., Titov, M., Baffioni, S., Beaudette, F., Busson, P., Chariot, C., Daci, N., Dahms, T., Dalchenko, M., Dobrzynski, L., Florent, A., de Cassagnac, R. Granier, Haguenauer, M., Mine, P., Mironov, C., Naranjo, I. N., Nguyen, M., Ochando, C., Paganini, P., Sabes, D., Salerno, R., Sirois, Y., Veelken, C., Yilmaz, Y., Zabi, A., Agram, J.-L., Andrea, J., Bloch, D., Brom, J.-M., Chabert, E. C., Collard, C., Conte, E., Drouhin, F., Fontaine, J.-C., Gele, D., Goerlach, U., Goetzmann, C., Juillot, P., Le Bihan, A.-C., Van Hove, P., Gadrat, S., Beauceron, S., Beaupere, N., Boudoul, G., Brochet, S., Chasserat, J., Chierici, R., Contardo, D., Depasse, P., El Mamouni, H., Fan, J., Fay, J., Gascon, S., Gouzevitch, M., Ille, B., Kurca, T., Lethuillier, M., Mirabito, L., Perries, S., Alvarez, J. D. 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S., Kirschenmann, H., Klanner, R., Kogler, R., Lange, J., Marchesini, I., Ott, J., Peiffer, T., Pietsch, N., Poehlsen, J., Rathjens, D., Sander, C., Schettler, H., Schleper, P., Schlieckau, E., Schmidt, A., Seidel, M., Sola, V., Stadie, H., Steinbrueck, G., Troendle, D., Usai, E., Vanelderen, L., Barth, C., Baus, C., Berger, J., Boeser, C., Butz, E., Chwalek, T., De Boer, W., Descroix, A., Dierlamm, A., Feindt, M., Guthoff, M., Hartmann, F., Hauth, T., Held, H., Hoffmann, K. H., Husemann, U., Katkov, I., Kornmayer, A., Kuznetsova, E., Pardo, P. Lobelle, Martschei, D., Mozer, M. U., Mueller, Th, Niegel, M., Nuernberg, A., Oberst, O., Quast, G., Rabbertz, K., Ratnikov, F., Roecker, S., Schilling, F.-P., Schott, G., Simonis, H. J., Stober, F. 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F., Prosper, H., Veeraraghavan, V., Weinberg, M., Baarmand, M. M., Dorney, B., Hohlmann, M., Kalakhety, H., Yumiceva, F., Adams, M. R., Apanasevich, L., Bazterra, V. E., Betts, R. R., Bucinskaite, I., Cavanaugh, R., Evdokimov, O., Gauthier, L., Gerber, C. E., Hofman, Dj, Khalatyan, S., Kurt, P., Moon, D. H., O'Brien, C., Silkworth, C., Turner, P., Varelas, N., Akgun, U., Albayrak, E. A., Bilki, B., Clarida, W., Dilsiz, K., Duru, F., Merlo, J.-P., Mermerkaya, H., Mestvirishvili, A., Moeller, A., Nachtman, J., Ogul, H., Onel, Y., Ozuk, F., Sen, S., Tan, P., Tiras, E., Wetzel, J., Yetkin, T., Yi, K., Barnett, B. A., Blumenfeld, B., Bolognesi, S., Fehling, D., Gritsan, A. V., Maksimovic, P., Martin, C., Swartz, M., Whitbeck, A., Baringer, P., Bean, A., Benelli, G., Kenny, R. P., Murray, M., Noonan, D., Sanders, S., Sekaric, J., Stringer, R., Wang, Q., Wood, J. S., Barfuss, A. F., Chakaberia, I., Ivanov, A., Khalil, S., Makouski, M., Maravin, Y., Saini, L. K., Shrestha, S., Svintradze, I., Gronberg, J., Lange, D., Rebassoo, F., Wright, D., Baden, A., Calvert, B., Eno, S. C., Gomez, J. A., Hadley, N. J., Kellogg, R. G., Kolberg, T., Lu, Y., Marionneau, M., Mignerey, A. C., Pedro, K., Skuja, A., Temple, J., Tonjes, M. B., Tonwar, S. C., Apyan, A., Barbieri, R., Bauer, G., Busza, W., Cali, I. A., Chan, M., Di Matteo, L., Dutta, V., Ceballos, G. Gomez, Goncharov, M., Gulhan, D., Kiute, M., Lai, Y. S., Lee, Y.-J., Levin, A., Luckey, P. D., Ma, T., Paus, C., Ralph, D., Roland, C., Roland, G., Stephans, G. S. F., Stockli, F., Sumorok, K., Velicanu, D., Veverka, J., Wyslouch, B., Yang, M., Yoon, A. S., Zanetti, M., Zhukova, V., Dahmes, B., De Benedetti, A., Gude, A., Kao, S. C., Klapoetke, K., Kubota, Y., Mans, J., Pastika, N., Rusack, R., Singovsky, A., Tambe, N., Turkewitz, J., Acosta, J. G., Cremaldi, L. M., Kroeger, R., Oliveros, S., Perera, L., Rahmat, R., Sanders, D. A., Summers, D., Avdeeva, E., Bloom, K., Bose, S., Claes, D. R., Dominguez, A., Suarez, R. Gonzalez, Keller, J., Kravchenko, I., Lazo-Flores, J., Malik, S., Meier, F., Snow, G. R., Dolen, J., Godshalk, A., Iashvili, I., Jain, S., Kharchilava, A., Kumar, A., Rappoccio, S., Wan, Z., Alverson, G., Barberis, E., Baumgartel, D., Chasco, M., Haley, J., Massironi, A., Nash, D., Orimoto, T., Trocino, Wood, D., Zhang, J., Anastassov, A., Hahn, K. A., Kubik, A., Lusito, L., Mucia, N., Odell, N., Pollack, B., Pozdnyakov, A., Schmitt, M., Stoynev, S., Sung, K., Velasco, M., Won, S., Berry, D., Brinkerhoff, A., Chan, K. M., Drozdetskiy, A., Hildreth, M., Jessop, C., Karmgard, D. J., Kolb, J., Lannon, K., Luo, W., Lynch, S., Marinelli, N., Morse, D. M., Pearson, T., Planer, M., Ruchti, R., Slaunwhite, J., Valls, N., Wayne, M., Wolf, M., Antonelli, L., Bylsma, B., Durkin, L. S., Flowers, S., Hill, C., Hughes, R., Kotov, K., Ling, T. Y., Puigh, D., Rodenburg, M., Smith, G., Vuosalo, C., Winer, B. L., Wolfe, H., Wulsin, H. W., Berry, E., Elmer, P., Halyo, V., Hebda, P., Hegeman, J., Hunt, A., Jindal, P., Koay, S. A., Lujan, P., Marlow, D., Medvedeva, T., Mooney, M., Olsen, J., Piroue, P., Quan, X., Raval, A., Saka, H., Stickland, D., Tully, C., Werner, J. S., Zenz, S. C., Zuranski, A., Brownson, E., Lopez, A., Mendez, H., Vargas, J. E. Ramirez, Alagoz, E., Benedetti, D., Bolla, G., Bortoletto, D., De Mattia, M., Everett, A., Hu, Z., Jones, M., Jung, K., Kress, M., Leonardo, N., Pegna, D. Lopes, Maroussov, V., Merkel, P., Miller, D. H., Neumeister, N., Radburn-Smith, B. C., Shipsey, I., Silvers, D., Svyatkovskiy, A., Wang, F., Xie, W., Xu, L., Yoo, H. D., Zablocki, J., Zheng, Y., Parashar, N., Adair, A., Akgun, B., Ecklund, K. M., Geurts, F. J. M., Li, W., Michlin, B., Padley, B. P., Redjimi, R., Roberts, J., Zabel, J., Betchart, B., Bodek, A., Covarelli, R., de Barbaro, P., Demina, R., Eshaq, Y., Garcia-Bellido, T. Ferbel A., Goldenzweig, P., Han, J., Harel, A., Miner, D. C., Petrillo, G., Vishnevskiy, D., Zielinski, M., Bhatti, A., Ciesielski, R., Demortier, L., Goulianos, K., Lungu, G., Malik, S., Mesropian, C., Arora, S., Barker, A., Chou, J. P., Contreras-Campana, C., Contreras-Campana, E., Duggan, D., Ferencek, D., Gershtein, Y., Gray, R., Halkiadakis, E., Hidas, D., Lath, A., Panwalkar, S., Park, M., Patel, R., Rekovic, V., Robles, J., Salur, S., Schnetzer, S., Seitz, C., Somaiwar, S., Stone, R., Thomas, S., Thomassen, P., Walker, M., Rose, K., Spanier, S., Yang, Z. C., York, A., Bouhali, O., Eusebi, R., Flanagan, W., Gilmore, J., Kamon, T., Khotilovich, V., Krutelyov, V., Montalvo, R., Osipenkov, I., Pakhotin, Y., Perloff, A., Roe, J., Safonov, A., Sakuma, T., Suarez, I., Tatarinov, A., Toback, D., Akchurin, N., Cowden, C., Damgov, J., Dragoiu, C., Dudero, P. R., Kovitanggoon, K., Kunori, S., Lee, S. W., Libeiro, T., Volobouev, I., Appelt, E., Delannoy, A. G., Greene, S., Gurrola, A., Johns, W., Maguire, C., Mao, Y., Melo, A., Sharma, M., Sheldon, P., Snook, B., Tuo, S., Velkovska, J., Arenton, M. W., Boutle, S., Cox, B., Francis, B., Goodell, J., Hirosky, R., Ledovskoy, A., Lin, C., Neu, C., Wood, J., Gollapinni, S., Harr, R., Karchin, P. E., Don, C. Kottachchi Kankanamge, Lamichhane, P., Sakharov, A., Belknap, D. A., Borrello, L., Carlsmith, D., Cepeda, M., Dasu, S., Duric, S., Friis, E., Grothe, M., Hall-Wilton, R., Herndon, M., Herve, A., Klabbers, P., Klukas, J., Lanaro, A., Loveless, R., Mohapatra, A., Ojalvo, I., Perry, T., Pierro, G. A., Polese, G., Ross, I., Sarangi, T., Savin, A., Smith, W. H., Aziz, T., Banerjee, S., Chatterjee, R. M., Dugad, S., Ganguly, S., Ghosh, S., Guchait, M., Gurtu, A., Kole, G., Kumar, S., Maity, M., Majumder, G., Mazumdar, K., Mohanty, G. B., Parida, B., Sudhakar, K., Wickramage, N.
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Abstract/Description: The invariance of the standard model (SM) under the CPT transformation predicts equality of particle and antiparticle masses. This prediction is tested by measuring the mass difference between the top quark and antiquark (Delta m(t) = m(t) - m((t) over bar)) that are produced in pp collisions at a center-of-mass energy of 8 TeV, using events with a muon or an electron and at least four jets in the final state. The analysis is based on data corresponding to an integrated luminosity of 19.6 fb(...
Show moreThe invariance of the standard model (SM) under the CPT transformation predicts equality of particle and antiparticle masses. This prediction is tested by measuring the mass difference between the top quark and antiquark (Delta m(t) = m(t) - m((t) over bar)) that are produced in pp collisions at a center-of-mass energy of 8 TeV, using events with a muon or an electron and at least four jets in the final state. The analysis is based on data corresponding to an integrated luminosity of 19.6 fb(-1) collected by the CMS experiment at the LHC, and yields a value of Delta m(t) = 0.15 0.19 (stat) +/- 0.09(syst) GeV, which is consistent with the SM expectation. This result is significantly more precise than previously reported measurements. (C) 2017 The Author(s). Published by Elsevier B.V.
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Date Issued: 2017-07-10
Identifier: FSU_libsubv1_wos_000404196500007, 10.1016/j.physletb.2017.04.028
Format: Citation

Title: Demographics As Predictors Of Suicidal Thoughts And Behaviors: A Meta-analysis.
Creator: Huang, Xieyining, Ribeiro, Jessica D., Musacchio, Katherine M., Franklin, Joseph C.
Abstract/Description: Background Certain demographic factors have long been cited to confer risk or protection for suicidal thoughts and behaviors. However, many studies have found weak or non-significant effects. Determining the effect strength and clinical utility of demographics as predictors is crucial for suicide risk assessment and theory development. As such, we conducted a meta-analysis to determine the effect strength and clinical utility of demographics as predictors. Methods We searched PsycInfo, PubMed...
Show moreBackground Certain demographic factors have long been cited to confer risk or protection for suicidal thoughts and behaviors. However, many studies have found weak or non-significant effects. Determining the effect strength and clinical utility of demographics as predictors is crucial for suicide risk assessment and theory development. As such, we conducted a meta-analysis to determine the effect strength and clinical utility of demographics as predictors. Methods We searched PsycInfo, PubMed, and GoogleScholar for studies published before January 1st, 2015. Inclusion criteria required that studies use at least one demographic factor to longitudinally predict suicide ideation, attempt, or death. The initial search yielded 2,541 studies, 159 of which were eligible. A total of 752 unique statistical tests were included in analysis. Results Suicide death was the most commonly studied outcome, followed by attempt and ideation. The average follow-up length was 9.4 years. The overall effects of demographic factors studied in the field as risk factors were significant but weak, and that of demographic factors studied as protective factors were non-significant. Adjusting for publication bias further reduced effect estimates. No specific demographic factors appeared to be strong predictors. The effects were consistent across multiple moderators. Conclusions At least within the narrow methodological constraints of the existing literature, demographic factors were statistically significant risk factors, but not protective factors. Even as risk factors, demographics offer very little improvement in predictive accuracy. Future studies that go beyond the limitations of the existing literature are needed to further understand the effects of demographics.
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Date Issued: 2017-07-10
Identifier: FSU_libsubv1_wos_000405544800077, 10.1371/journal.pone.0180793
Format: Citation

Title: Evidence For Rapid Weathering Response To Climatic Warming During The Toarcian Oceanic Anoxic Event.
Creator: Them, Theodore R., Gill, Benjamin C., Selby, David, Grocke, Darren R., Friedman, Richard M., Owens, Jeremy D.
Abstract/Description: Chemical weathering consumes atmospheric carbon dioxide through the breakdown of silicate minerals and is thought to stabilize Earth's long-term climate. However, the potential influence of silicate weathering on atmospheric pCO(2) levels on geologically short timescales (10(3)-10(5) years) remains poorly constrained. Here we focus on the record of a transient interval of severe climatic warming across the Toarcian Oceanic Anoxic Event or T-OAE from an open ocean sedimentary succession from...
Show moreChemical weathering consumes atmospheric carbon dioxide through the breakdown of silicate minerals and is thought to stabilize Earth's long-term climate. However, the potential influence of silicate weathering on atmospheric pCO(2) levels on geologically short timescales (10(3)-10(5) years) remains poorly constrained. Here we focus on the record of a transient interval of severe climatic warming across the Toarcian Oceanic Anoxic Event or T-OAE from an open ocean sedimentary succession from western North America. Paired osmium isotope data and numerical modelling results suggest that weathering rates may have increased by 215% and potentially up to 530% compared to the pre-event baseline, which would have resulted in the sequestration of significant amounts of atmospheric CO2. This process would have also led to increased delivery of nutrients to the oceans and lakes stimulating bioproductivity and leading to the subsequent development of shallow-water anoxia, the hallmark of the T-OAE. This enhanced bioproductivity and anoxia would have resulted in elevated rates of organic matter burial that would have acted as an additional negative feedback on atmospheric pCO2 levels. Therefore, the enhanced weathering modulated by initially increased pCO2 levels would have operated as both a direct and indirect negative feedback to end the T-OAE.
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Date Issued: 2017-07-10
Identifier: FSU_libsubv1_wos_000405180900076, 10.1038/s41598-017-05307-y
Format: Citation

Title: Search For Heavy Gauge W ' Bosons In Events With An Energetic Lepton And Large Missing Transverse Momentum At Root S=13tev.
Creator: Khachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth...
Show moreKhachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schieck, J., Strauss, J., Waltenberger, W., Wulz, C.-E., Dvornikov, O., Makarenko, V., Zykunov, V., Mossolov, V., Shumeiko, N., Gonzalez, J. Suarez, Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., Van De Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, F., D'Hondt, J., Daci, N., De Bruyn, I., Deroover, K., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Leonard, A., Luetic, J., Maerschalk, T., Marinov, A., Randle-Conde, A., Seva, T., Vander Velde, C., Vanlaer, P., Yonamine, R., Zenoni, F., Zhang, F., Cimmino, A., Cornelis, T., Dobur, D., Fagot, A., Garcia, G., Gul, M., Khvastunov, I., Poyraz, D., Salva, S., Schofbeck, R., Sharma, A., Tytgat, M., Van Driessche, W., Yazgan, E., Zaganidis, N., Bakhshiansohi, H., Beluffi, C., Bondu, O., Brochet, S., Bruno, G., Caudron, A., De Visscher, S., Delaere, C., Delcourt, M., Francois, B., Giammanco, A., Jafari, A., Jez, P., Komm, M., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Nuttens, C., Piotrzkowski, K., Quertenmont, L., Selvaggi, M., Marono, M. Vidal, Wertz, S., Beliy, N., Aida Junior, W. L., Alves, F. L., Alves, G. A., Brito, L., Hensel, C., Moraes, A., Pol, M. E., Rebello Teles, P., Belchior Batista Das Chagas, E., Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Huertas Guativa, L. M., Malbouisson, H., Matos Figueiredo, D., Mora Herrera, C., Mundim, L., Nogima, H., Prado Da Silva, W. L., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Vilela Pereira, A., Ahuja, S., Bernardes, C. A., Dogra, S., Fernandez Perez Tomei, T. R., Gregores, E. M., Mercadante, P. G., Moon, C. S., Novaes, S. F., Padula, Sandra S., Romero Abad, D., Ruiz Vargas, J. C., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Rodozov, M., Stoykova, S., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Litov, L., Pavlov, B., Petkov, P., Fang, W., Ahmad, M., Bian, J. G., Chen, G. M., Chen, H. S., Chen, M., Chen, Y., Cheng, T., Jiang, C. H., Leggat, D., Romeo, F., Shaheen, S. M., Spiezia, A., Tao, J., Wang, C., Wang, Z., Zhang, H., Zhao, J., Ban, Y., Chen, G., Li, Q., Liu, S., Mao, Y., Qian, S. J., Wang, D., Xu, Z., Avila, C., Cabrera, A., Chaparro Sierra, L. F., Florez, C., Gomez, J. P., Gonzalez Hernandez, C. F., Ruiz Alvarez, J. D., Sanabria, J. C., Godinovic, N., Lelas, D., Puljak, I., Ribeiro Cipriano, P. M., Sculac, T., Antunovic, Z., Kovac, M., Brigljevic, V., Ferencek, D., Kadija, K., Micanovic, S., Sudic, L., Susa, T., Attikis, A., Mavromanolakis, G., Mousa, J., Nicolaou, C., Ptochos, F., Razis, P. A., Rykaczewski, H., Tsiakkouri, D., Finger, M., Finger, M., Jarrin, E. Carrera, Abdelalim, A. A., Mohammed, Y., Salama, E., Calpas, B., Kadastik, M., Murumaa, M., Perrini, L., Raidal, M., Tiko, A., Veelken, C., Eerola, P., Pekkanen, J., Voutilainen, M., Harkonen, J., Jarvinen, T., Karimaki, V., Kinnunen, R., Lampen, T., Lassila-Perini, K., Lehti, S., Linden, T., Luukka, P., Tuominiemi, J., Tuovinen, E., Wendland, L., Talvitie, J., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Fabbro, B., Faure, J. L., Favaro, C., Ferri, F., Ganjour, S., Ghosh, S., Givernaud, A., Gras, P., de Monchenault, G. Hamel, Jarry, P., Kucher, I., Locci, E., Machet, M., Malcles, J., Rander, J., Rosowsky, A., Titov, M., Zghiche, A., Abdulsalam, A., Antropov, I., Baffioni, S., Beaudette, F., Busson, P., Cadamuro, L., Chapon, E., Chariot, C., Davignon, O., de Cassagnac, R. Granier, Jo, M., Lisniak, S., Mine, P., Nguyen, M., Ochando, C., Ortona, G., Paganini, P., Pigard, P., Regnard, S., Salerno, R., Sirois, Y., Strebler, T., Yilmaz, Y., Zabi, A., Agram, J.-L., Andrea, J., Aubin, A., Bloch, D., Brom, J.-M., Buttignol, M., Chabert, E. C., Chanon, N., Collard, C., Conte, E., Coubez, X., Fontaine, J.-C., Gele, D., Goerlach, U., Le Bihan, A.-C., Skovpen, K., Van Hove, P., Gadrat, S., Beauceron, S., Bernet, C., Boudoul, G., Bouvier, E., Montoya, C. A. Carrillo, Chierici, R., Contardo, D., Courbon, B., Depasse, P., El Mamouni, H., Fan, J., Fay, J., Gascon, S., Gouzevitch, M., Grenier, G., Ille, B., Lagarde, F., Laktineh, I. B., Lethuillier, M., Mirabito, L., Pequegnot, A. L., Perries, S., Popov, A., Sabes, D., Sordini, V., Vander Donckt, M., Verdier, P., Viret, S., Toriashvili, T., Tsamalaidze, Z., Autermann, C., Beranek, S., Feld, L., Heister, A., Kiesel, M. K., Klein, K., Lipinski, M., Ostapchuk, A., Preuten, M., Raupach, F., Schael, S., Schomakers, C., Schulz, J., Verlage, T., Weber, H., Zhukov, V., Albert, A., Bispinck, F. F., Brodski, M., Dietz-Laursonn, E., Duchardt, D., Endres, M., Erdmann, M., Erdweg, S., Esch, T., Fischer, R., Gueth, A., Hamer, M., Hebbeker, T., Heidemann, C., Hoepfner, K., Knutzen, S., Merschmeyer, M., Meyer, A., Millet, P., Mukherjee, S., Olschewski, M., Padeken, K., Pook, T., Radziej, M., Reithler, H., Rieger, M., Scheuch, F., Sonnenschein, L., Teyssier, D., Thueer, S., Cherepanov, V., Fluegge, G., Hoehle, F., Kargoll, B., Kress, T., Kuensken, A., Lingemann, J., Mueller, T., Nehrkorn, A., Nowack, A., Nugent, I. M., Pistone, C., Pooth, O., Stahl, A., Martin, M. Aldaya, Arndt, T., Asawatangtrakuldee, C., Beernaert, K., Behnke, O., Behrens, U., Bin Anuar, A. A., Borras, K., Campbell, A., Connor, P., Contreras-Campana, C., Costanza, F., Pardos, C. Diez, Dolinska, G., Eckerlin, G., Eckstein, D., Eichhorn, T., Eren, E., Gallo, E., Garcia, J. Garay, Geiser, A., Gizhko, A., Luyando, J. M. Grados, Gunnellini, P., Harb, A., Hauk, J., Hempel, M., Jung, H., Kalogeropoulos, A., Karacheban, O., Kasemann, M., Keaveney, J., Kleinwort, C., Korol, I., Krucker, D., Lange, W., Lelek, A., Leonard, J., Lipka, K., Lobanov, A., Lohmann, W., Mankel, R., Melzer-Pellmann, I.-A., Meyer, A. B., Mittag, G., Mnich, J., Mussgiller, A., Ntomari, E., Pitzl, D., Placakyte, R., Raspereza, A., Roland, B., Sahin, M. O., Saxena, P., Schoerner-Sadenius, T., Seitz, C., Spannagel, S., Stefaniuk, N., Van Onsem, G. P., Walsh, R., Wissing, C., Blobel, V., Vignali, M. Centis, Draeger, A. R., Dreyer, T., Garutti, E., Gonzalez, D., Haller, J., Hoffmann, M., Junkes, A., Klanner, R., Kogler, R., Kovalchuk, N., Kutzner, V., Lapsien, T., Lenz, T., Marchesini, I., Marconi, D., Meyer, M., Niedziela, M., Nowatschin, D., Pantaleo, F., Peiffer, T., Perieanu, A., Poehlsen, J., Sander, C., Scharf, C., Schleper, P., Schmidt, A., Schumann, S., Schwandt, J., Stadie, H., Steinbruck, G., Stober, F. M., Stover, M., Tholen, H., Troendle, D., Usai, E., Vanelderen, L., Vanhoefer, A., Vormwald, B., Akbiyik, M., Barth, C., Baur, S., Baus, C., Berger, J., Butz, E., Caspart, R., Chwalek, T., Colombo, F., De Boer, W., Dierlamm, A., Fink, S., Freund, B., Friese, R., Giffels, M., Gilbert, A., Goldenzweig, P., Haitz, D., Hartmann, F., Heindl, S. M., Husemann, U., Katkov, I., Kudella, S., Pardo, P. Lobelle, Mildner, H., Mozer, M. U., Mueller, Th, Plagge, M., Quast, G., Rabbertz, K., Rocker, S., Roscher, F., Schroder, M., Shvetsov, I., Sieber, G., Simonis, H. J., Ulrich, R., Wagner-Kuhr, J., Wayand, S., Weber, M., Weiler, T., Williamson, S., Wohrmann, C., Wolf, R., Anagnostou, G., Daskalakis, G., Geralis, T., Giakoumopoulou, V. A., Kyriakis, A., Loukas, D., Topsis-Giotis, I., Kesisoglou, S., Panagiotou, A., Saoulidou, N., Tziaferi, E., Evangelou, I., Flouris, G., Foudas, C., Kokkas, P., Loukas, N., Manthos, N., Papadopoulos, I., Paradas, E., Filipovic, N., Bencze, G., Hajdu, C., Hidas, P., Horvath, D., Sikler, F., Veszpremi, V., Vesztergombi, G., Zsigmond, A. J., Beni, N., Czellar, S., Karancsi, J., Makovec, A., Molnar, J., Szillasi, Z., Bartok, M., Raics, P., Trocsanyi, Z. L., Ujvari, B., Bahinipati, S., Choudhary, S., Mal, P., Mandal, K., Nayak, A., Sahoo, D. K., Sahoo, N., Swain, S. K., Bansal, S., Beni, S. B., Bhatnagar, V., Chawla, R., Bhawandeep, U., Kalsi, A. K., Kaur, A., Kaur, M., Kumar, R., Kumari, P., Mehta, A., Mittal, M., Singh, J. B., Walia, G., Kumar, Ashok, Bhardwaj, A., Choudhary, B. C., Garg, R. 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Lopes, Lykken, J., Maeshima, K., Magini, N., Marraffino, J. M., Maruyama, S., Mason, D., McBride, P., Merkel, P., Mrenna, S., Nahn, S., Newman-Holmes, C., O'Dell, V., Pedro, K., Prokofyev, O., Rakness, G., Ristori, L., Sexton-Kennedy, E., Soha, A., Spalding, W. J., Spiegel, L., Stoynev, S., Strait, J., Strobbe, N., Taylor, L., Tkaczyk, S., Tran, N. V., Uplegger, L., Vaandering, E. W., Vernieri, C., Verzocchi, M., Vidal, R., Wang, M., Weber, H. A., Whitbeck, A., Wu, Y., Acosta, D., Avery, P., Bortignon, P., Bourilkov, D., Brinkerhoff, A., Carnes, A., Carver, M., Curry, D., Das, S., Field, R. D., Furic, I. K., Konigsberg, J., Korytov, A., Low, J. F., Ma, P., Matchev, K., Mei, H., Mitselmakher, G., Rank, D., Shchutska, L., Sperka, D., Thomas, L., Wang, J., Wang, S., Yelton, J., Linn, S., Markowitz, P., Martinez, G., Rodriguez, J. L., Ackert, A., Adams, J. R., Adams, T., Askew, A., Bein, S., Diamond, B., Hagopian, S., Hagopian, V., Johnson, K. F., Khatiwada, A., Prosper, H., Santra, A., Baarmand, M. M., Bhopatkar, V., Colafranceschi, S., Hohlmann, M., Noonan, D., Roy, T., Yumiceva, E., Adams, M. R., Apanasevich, L., Berry, D., Betts, R. R., Bucinskaite, I., Cavanaugh, R., Evdokimov, O., Gauthier, L., Gerber, C. E., Hofman, D. J., Jung, K., Kurt, P., O'Brien, C., Gonzalez, I. D. Sandoval, Turner, P., Varelas, N., Wang, H., Wu, Z., Zakaria, M., Zhang, J., Bilki, B., Clarida, W., Dilsiz, K., Durgut, S., Gandrajula, R. P., Haytmyradov, M., Khristenko, V., Merlo, J.-P., Mermerkaya, H., Mestvirishvili, A., Moeller, A., Nachtman, J., Ogul, H., Onel, Y., Ozok, F., Penzo, A., Snyder, C., Tiras, E., Wetzel, J., Yi, K., Anderson, I., Blumenfeld, B., Cocoros, A., Eminizer, N., Fehling, D., Feng, L., Gritsan, A. V., Maksimovic, P., Martin, C., Osherson, M., Roskes, J., Sarica, U., Swartz, M., Xiao, M., Xin, Y., You, C., Al-Bataineh, A., Baringer, P., Bean, A., Boren, S., Bowen, J., Bruner, C., Castle, J., Forthomme, L., Kenny, R. P., Khalil, S., Kropivnitskaya, A., Majumder, D., Mcbrayer, W., Murray, M., Sanders, S., Stringer, R., Takaki, J. D. Tapia, Wang, Q., Ivanov, A., Kaadze, K., Maravin, Y., Mohammadi, A., Saini, L. K., Skhirtladze, N., Toda, S., Rebassoo, F., Wright, D., Anelli, C., Baden, A., Baron, O., Belloni, A., Calvert, B., Eno, S. C., Ferraioli, C., Gomez, J. A., Hadley, N. J., Jabeen, S., Kellogg, R. G., Kolberg, T., Kunkle, J., Lu, Y., Mignerey, A. C., Ricci-Tam, F., Shin, Y. H., Skuja, A., Tonjes, M. B., Tonwar, S. C., Abercrombie, D., Allen, B., Apyan, A., Barbieri, R., Baty, A., Bi, R., Bierwagen, K., Brandt, S., Busza, W., Cali, I. A., Demiragli, Z., Di Matteo, L., Ceballos, G. Gomez, Goncharov, M., Hsu, D., Iiyama, Y., Innocenti, G. M., Klute, M., Kovalskyi, D., Krajczar, K., Lai, Y. S., Lee, Y.-J., Levin, A., Luckey, P. D., Maier, B., Marini, A. C., Mcginn, C., Mironov, C., Narayanan, S., Niu, X., Paus, C., Roland, C., Roland, G., Salfeld-Nebgen, J., Stephans, G. S. F., Sumorok, K., Tatar, K., Varma, M., Velicanu, D., Veverka, J., Wang, J., Wang, T. W., Wyslouch, B., Yang, M., Zhukova, V., Benvenuti, A. C., Chatterjee, R. M., Evans, A., Finkel, A., Gude, A., Hansen, P., Kalafut, S., Kao, S. C., Kubota, Y., Lesko, Z., Mans, J., Nourbakhsh, S., Ruckstuhl, N., Rusack, R., Tambe, N., Turkewitz, J., Acosta, J. G., Oliveros, S., Avdeeva, E., Bartek, R., Bloom, K., Claes, D. R., Dominguez, A., Fangmeier, C., Suarez, R. Gonzalez, Kamalieddin, R., Kravchenko, I., Rodrigues, A. Malta, Meier, F., Monroy, J., Siado, J. E., Snow, G. R., Stieger, B., Alyari, M., Dolen, J., George, J., Godshalk, A., Harrington, C., Iashvili, I., Kaisen, J., Kharchilava, A., Kumar, A., Parker, A., Rappoccio, S., Roozbahani, B., Alverson, G., Barberis, E., Hortiangtham, A., Massironi, A., Morse, D. M., Nash, D., Orimoto, T., De Lima, R. Teixeira, Trocino, D., Wang, R.-J., Wood, D., Bhattacharya, S., Hahn, K. A., Kubik, A., Kumar, A., Mucia, N., Odell, N., Pollack, B., Schmitt, M. H., Sung, K., Trovato, M., Dev, N., Hildreth, M., Anampa, K. Hurtado, Jessop, C., Karmgard, D. J., Kellams, N., Lannon, K., Marinelli, N., Meng, F., Mueller, C., Musienko, Y., Planer, M., Reinsvold, A., Ruchti, R., Smith, G., Taroni, S., Wayne, Wolf, M., Woodard, A., Alimena, J., Antonelli, L., Brinson, J., Bylsma, B., Durkin, L. S., Flowers, S., Francis, B., Hart, A., Hill, C., Hughes, R., Ji, W., Liu, B., Luo, W., Puigh, D., Winer, B. L., Wulsin, H. W., Cooperstein, S., Driga, O., Elmer, P., Hardenbrook, J., Hebda, P., Lange, D., Luo, J., Marlow, D., Mc Donald, J., Medvedeva, T., Mei, K., Mooney, M., Olsen, J., Palmer, C., Piroue, P., Stickland, D., Svyatkovskiy, A., Tully, C., Zuranski, A., Malik, S., Barker, A., Barnes, V. E., Folgueras, S., Gutay, L., Jha, M. K., Jones, M., Jung, A. W., Miller, D. H., Neumeister, N., Schulte, J. F., Shi, X., Sun, J., Wang, F., Xie, W., Xu, L., Parashar, N., Stupak, J., Adair, A., Akgun, B., Chen, Z., Ecklund, K. M., Geurts, F. J. M., Guilbaud, M., Li, W., Michlin, B., Northup, M., Padley, B. P., Redjimi, R., Roberts, J., Rorie, J., Tu, Z., Zabel, J., Betchart, B., Bodek, A., de Barbaro, P., Demina, R., Duh, Y. T., Ferbel, T., Galanti, M., Garcia-Bellido, A., Han, J., Hindrichs, O., Khukhunaishvili, A., Lo, K. H., Tan, P., Verzetti, M., Agapitos, A., Chou, J. P., Contreras-Campana, E., Gershtein, Y., Espinosa, T. A. Gomez, Halkiadakis, E., Heindl, M., Hidas, D., Hughes, E., Kaplan, S., Elayavalli, R. Kunnawalkam, Kyriacou, S., Lath, A., Nash, K., Saka, H., Salur, S., Schnetzer, S., Sheffield, D., Somalwar, S., Stone, R., Thomas, S., Thomassen, P., Walker, M., Delannoy, A. G., Foerster, M., Heideman, J., Riley, G., Rose, K., Spanier, S., Thapa, K., Bouhali, O., Celik, A., Dalchenko, M., De Mattia, M., Delgado, A., Dildick, S., Eusebi, R., Gilmore, J., Huang, T., Juska, E., Kamon, T., Mueller, R., Pakhotin, Y., Patel, R., Perloff, A., Pernie, L., Rathjens, D., Rose, A., Safonov, A., Tatarinov, A., Ulmer, K. A., Akchurin, N., Cowden, C., Damgov, J., De Guio, F., Dragoiu, C., Dudero, P. R., Faulkner, J., Gurpinar, E., Kunori, S., Lamichhane, K., Lee, S. W., Libeiro, T., Peltola, T., Undleeb, S., Volobouev, I., Wang, Z., Greene, S., Gurrola, A., Janjam, R., Johns, W., Maguire, C., Melo, A., Ni, H., Sheldon, P., Tuo, S., Velkovska, J., Xu, Q., Arenton, M. W., Barria, P., Cox, B., Goodell, J., Hirosky, R., Ledovskoy, A., Li, H., Neu, C., Sinthuprasith, T., Sun, X., Wang, Y., Wolfe, E., Xia, F., Clarke, C., Harr, R., Karchin, P. E., Sturdy, J., Belknap, D. A., Caillol, C., Dasu, S., Dodd, L., Duric, S., Gomber, B., Grothe, M., Herndon, M., Herve, A., Klabbers, P., Lanaro, A., Levine, A., Long, K., Loveless, R., Ojalvo, I., Perry, T., Pierro, G. A., Polese, G., Ruggles, T., Savin, A., Smith, N., Smith, W. H., Taylor, D., Woods, N.
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Abstract/Description: A search is presented for W' bosons in events with an electron or muon and large missing transverse momentum, using proton-proton collision data at root s = 13 TeV collected with the CMS detector in 2015 and corresponding to an integrated luminosity of 2.3 fb(-1). No evidence of an excess of events relative to the standard model expectations is observed. For a W' boson described by the sequential standard model, upper limits at 95% confidence level are set on the product of the production...
Show moreA search is presented for W' bosons in events with an electron or muon and large missing transverse momentum, using proton-proton collision data at root s = 13 TeV collected with the CMS detector in 2015 and corresponding to an integrated luminosity of 2.3 fb(-1). No evidence of an excess of events relative to the standard model expectations is observed. For a W' boson described by the sequential standard model, upper limits at 95% confidence level are set on the product of the production cross section and branching fraction and lower limits are established on the new boson mass. Masses below 4.1 TeV are excluded combining electron and muon decay channels, significantly improving upon the results obtained with the 8 TeV data. Exclusion limits at 95% confidence level on the product of the W' production cross section and branching fraction are also derived in combination with the 8 TeV data. Finally, exclusion limits are set for the production of generic W' bosons decaying into this final state using a model-independent approach. (C) 2017 The Author. Published by Elsevier B.V.
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Date Issued: 2017-07-10
Identifier: FSU_libsubv1_wos_000404196500039, 10.1016/j.physletb.2017.04.043
Format: Citation

Title: An Intact Mcm10 Coiled-coil Interaction Surface Is Important For Origin Melting, Helicase Assembly And The Recruitment Of Pol-alpha To Mcm2-7.
Creator: Perez-Arnaiz, Patricia, Bruck, Irina, Colbert, Max K., Kaplan, Daniel L.
Abstract/Description: Mcm10 is an essential eukaryotic factor required for DNA replication. The replication fork helicase is composed of Cdc45, Mcm2-7 and GINS (CMG). DDK is an S-phase-specific kinase required for replication initiation, and the DNA primase-polymerase in eukaryotes is pol alpha. Mcm10 forms oligomers in vitro, mediated by the coiled-coil domain at the N-terminal region of the protein. We characterized an Mcm10 mutant at the N-terminal Domain (NTD), Mcm10-4A, defective for self-interaction. We...
Show moreMcm10 is an essential eukaryotic factor required for DNA replication. The replication fork helicase is composed of Cdc45, Mcm2-7 and GINS (CMG). DDK is an S-phase-specific kinase required for replication initiation, and the DNA primase-polymerase in eukaryotes is pol alpha. Mcm10 forms oligomers in vitro, mediated by the coiled-coil domain at the N-terminal region of the protein. We characterized an Mcm10 mutant at the N-terminal Domain (NTD), Mcm10-4A, defective for self-interaction. We found that the Mcm10-4A mutant was defective for stimulating DDK phosphorylation of Mcm2, binding to eighty-nucleotide ssDNA, and recruiting pol alpha to Mcm2-7 in vitro. Expression of wild-type levels of mcm10-4A resulted in severe growth and DNA replication defects in budding yeast cells, with diminished DDK phosphorylation of Mcm2. We then expressed the mcm10-4A in mcm5-bob1 mutant cells to bypass the defects mediated by diminished stimulation of DDK phosphorylation of Mcm2. Expression of wild-type levels of mcm10-4A in mcm5-bob1 mutant cells resulted in severe growth and DNA replication defects, along with diminished RPA signal at replication origins. We also detected diminished GINS and pol-alpha recruitment to the Mcm2-7 complex. We conclude that an intact Mcm10 coiled-coil interaction surface is important for originmelting, helicase assembly, and the recruitment of pol alpha to Mcm2-7.
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Date Issued: 2017-07-07
Identifier: FSU_libsubv1_wos_000404879000030, 10.1093/nar/gkx438
Format: Citation

Title: Tumoral Expression Of Drug And Xenobiotic Metabolizing Enzymes In Breast Cancer Patients Of Different Ethnicities With Implications To Personalized Medicine.
Creator: Li, Yan, Steppi, Albert, Zhou, Yidong, Mao, Feng, Miller, Philip Craig, He, Max M., Zhao, Tingting, Sun, Qiang, Zhang, Jinfeng
Abstract/Description: Drug and xenobiotic metabolizing enzymes (DXME) play important roles in drug responses and carcinogenesis. Recent studies have found that expression of DXME in cancer cells significantly affects drug clearance and the onset of drug resistance. In this study we compared the expression of DXME in breast tumor tissue samples from patients representing three ethnic groups: Caucasian Americans (CA), African Americans (AA), and Asian Americans (AS). We further combined DXME gene expression data...
Show moreDrug and xenobiotic metabolizing enzymes (DXME) play important roles in drug responses and carcinogenesis. Recent studies have found that expression of DXME in cancer cells significantly affects drug clearance and the onset of drug resistance. In this study we compared the expression of DXME in breast tumor tissue samples from patients representing three ethnic groups: Caucasian Americans (CA), African Americans (AA), and Asian Americans (AS). We further combined DXME gene expression data with eQTL data from the GTEx project and with allele frequency data from the 1000 Genomes project to identify SNPs that may be associated with differential expression of DXME genes. We identified substantial differences among CA, AA, and AS populations in the expression of DXME genes and in activation of pathways involved in drug metabolism, including those involved in metabolizing chemotherapy drugs that are commonly used in the treatment of breast cancer. These data suggest that differential expression of DXME may associate with health disparities in breast cancer outcomes observed among these three ethnic groups. Our study suggests that development of personalized treatment strategies for breast cancer patients could be improved by considering both germline genotypes and tumor specific mutations and expression profiles related to DXME genes.
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Date Issued: 2017-07-06
Identifier: FSU_libsubv1_wos_000404841100003, 10.1038/s41598-017-04250-2
Format: Citation

Title: Landau-level Spectroscopy Of Massive Dirac Fermions In Single-crystalline Zrte5 Thin Flakes.
Creator: Jiang, Y., Dun, Z. L., Zhou, H. D., Lu, Z., Chen, K.-W., Moon, S., Besara, T., Siegrist, T. M., Baumbach, R. E., Smirnov, D., Jiang, Z.
Abstract/Description: We report infrared magnetospectroscopy studies on thin crystals of an emerging Dirac material ZrTe5 near the intrinsic limit. The observed structure of the Landau-level transitions and zero-field infrared absorption indicate a two-dimensional Dirac-like electronic structure, similar to that in graphene but with a small relativistic mass corresponding to a 9.4-meV energy gap. Measurements with circularly polarized light reveal a significant electron-hole asymmetry, which leads to splitting of...
Show moreWe report infrared magnetospectroscopy studies on thin crystals of an emerging Dirac material ZrTe5 near the intrinsic limit. The observed structure of the Landau-level transitions and zero-field infrared absorption indicate a two-dimensional Dirac-like electronic structure, similar to that in graphene but with a small relativistic mass corresponding to a 9.4-meV energy gap. Measurements with circularly polarized light reveal a significant electron-hole asymmetry, which leads to splitting of the Landau-level transitions at high magnetic fields. Our model, based on the Bernevig-Hughes-Zhang effective Hamiltonian, quantitatively explains all observed transitions, determining the values of the Fermi velocity, Dirac mass (or gap), electron-hole asymmetry, and electron and hole g factors.
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Date Issued: 2017-07-05
Identifier: FSU_libsubv1_wos_000405026300001, 10.1103/PhysRevB.96.041101
Format: Citation

Title: Search For New Physics With Dijet Angular Distributions In Proton-proton Collisions At Root S = 13 Tev.
Creator: Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M...
Show moreSirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schieck, J., Strauss, J., Waltenberger, W., Wulz, C.-E., Dvornikov, O., Makarenko, V., Mossolov, V., Gonzalez, J. Suarez, Zykunov, V., Shumeiko, N., Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., Van De Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, F., D'Hondt, J., Daci, N., De Bruyn, I., Deroover, K., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Skovpen, K., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Leonard, A., Luetic, J., Maerschalk, T., Marinov, A., Randle-Conde, A., Seva, T., Vander Velde, C., Vanlaer, P., Vannerom, D., Yonamine, R., Zenoni, F., Zhang, F., Cimmino, A., Cornelis, T., Dobur, D., Fagot, A., Gul, M., Khvastunov, I., Poyraz, D., Salva, S., Schofbeck, R., Tytgat, M., Van Driessche, W., Yazgan, E., Zaganidis, N., Bakhshiansohi, H., Beluffi, C., Bondu, O., Brochet, S., Bruno, G., Caudron, A., De Visscher, S., Delaere, C., Delcourt, M., Francois, B., Giammanco, A., Jafari, A., Komm, M., Krintiras, G., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Piotrzkowski, K., Quertenmont, L., Selvaggi, M., Marono, M. Vidal, Wertz, S., Beliy, N., Alda Junior, W. L., Alves, F. L., Alves, G. A., Brito, L., Hensel, C., Moraes, A., Pol, M. E., Rebello Teles, P., Belchior Batista Das Chagas, E., Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Huertas Guativa, L. M., Malbouisson, H., Matos Figueiredo, D., Mora Herrera, C., Mundim, L., Nogima, H., Prado Da Silva, W. L., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Torres Da Silva De Araujo, F., Vilela Pereira, A., Ahuja, S., Bernardes, C. A., Dogra, S., Fernandez Perez Tomei, T. R., Gregores, E. M., Mercadante, P. G., Moon, C. S., Novaes, S. F., Padula, Sandra S., Romero Abad, D., Ruiz Vargas, J. C., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Rodozov, M., Stoykova, S., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Litov, L., Pavlov, B., Petkov, P., Fang, W., Ahmad, M., Bian, J. G., Chen, G. M., Chen, H. S., Chen, M., Chen, Y., Cheng, T., Jiang, C. H., Leggat, D., Liu, Z., Romeo, F., Ruan, M., Shaheen, S. M., Spiezia, A., Tao, J., Wang, C., Wang, Z., Zhang, H., Zhao, J., Ban, Y., Chen, G., Li, Q., Liu, S., Mao, Y., Qian, S. J., Wang, D., Xu, Z., Avila, C., Cabrera, A., Chaparro Sierra, L. F., Florez, C., Gomez, P., Gonzalez Hernandez, C. F., Ruiz Alvarez, J. D., Sanabria, J. C., Godinovic, N., Lelas, D., Puljak, I., Cipriano, P. M. Ribeiro, Sculac, T., Antunovic, Z., Kovac, M., Brigljevic, V., Ferencek, D., Kadija, K., Mesic, B., Susa, T., Attikis, A., Mavromanolakis, G., Mousa, J., Nicolaou, C., Ptochos, F., Razis, P. A., Rykaczewski, H., Tsiakkouri, D., Finger, M., Finger, M., Carrera Jarrin, E., Abdelalim, A. A., Mohammed, Y., Salama, E., Kadastik, M., Perrini, L., Raidal, M., Tiko, A., Veelken, C., Eerola, P., Pekkanen, J., Voutilainen, M., Harkonen, J., Jarvinen, T., Karimaki, V., Kinnunen, R., Lampen, T., Lassila-Perini, K., Lehti, S., Linden, T., Luukka, P., Tuominiemi, J., Tuovinen, E., Wendland, L., Talvitie, J., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Fabbro, B., Faure, J. L., Favaro, C., Ferri, F., Ganjour, S., Ghosh, S., Givernaud, A., Gras, P., de Monchenault, G. Hamel, Jarry, P., Kucher, I., Locci, E., Machet, M., Malcles, J., Rander, J., Rosowsky, A., Titov, M., Abdulsalam, A., Antropov, I., Baffioni, S., Beaudette, F., Busson, P., Cadamuro, L., Chapon, E., Charlot, C., Davignon, O., de Cassagnac, R. Granier, Jo, M., Lisniak, S., Mine, P., Nguyen, M., Ochando, C., Ortona, G., Paganini, P., Pigard, P., Regnard, S., Salerno, R., Sirois, Y., Strebler, T., Yilmaz, Y., Zabi, A., Zghiche, A., Agram, J.-L., Andrea, J., Aubin, A., Bloch, D., Brom, J.-M., Buttignol, M., Chabert, E. C., Chanon, N., Collard, C., Conte, E., Coubez, X., Fontaine, J.-C., Gele, D., Goerlach, U., Le Bihan, A.-C., Van Hove, P., Gadrat, S., Beauceron, S., Bernet, C., Boudoul, G., Montoya, C. A. Carrillo, Chierici, R., Contardo, D., Courbon, B., Depasse, P., El Mamouni, H., Fay, J., Gascon, S., Gouzevitch, M., Grenier, G., Ille, B., Lagarde, F., Laktineh, I. B., Lethuillier, M., Mirabito, L., Pequegnot, A. L., Perries, S., Popov, A., Sabes, D., Sordini, V., Vander Donckt, M., Verdier, P., Viret, S., Toriashvili, T., Tsamalaidze, Z., Autermann, C., Beranek, S., Feld, L., Kiesel, M. K., Klein, K., Lipinski, M., Preuten, M., Schomakers, C., Schulz, J., Verlage, T., Albert, A., Brodski, M., Dietz-Laursonn, E., Duchardt, D., Endres, M., Erdmann, M., Erdweg, S., Esch, T., Fischer, R., Gueth, A., Hamer, M., Hebbeker, T., Heidemann, C., Hoepfner, K., Knutzen, S., Merschmeyer, M., Meyer, A., Millet, P., Mukherjee, S., Olschewski, M., Padeken, K., Pook, T., Radziej, M., Reithler, H., Rieger, M., Scheuch, F., Sonnenschein, L., Teyssier, D., Thueer, S., Cherepanov, V., Fluegge, G., Kargoll, B., Kress, T., Kuensken, A., Lingemann, J., Mueller, T., Nehrkorn, A., Nowack, A., Pistone, C., Pooth, O., Stahl, A., Martin, M. Aldaya, Arndt, T., Asawatangtrakuldee, C., Beernaert, K., Behnke, O., Behrens, U., Bin Anuar, A. A., Borras, K., Campbell, A., Connor, P., Contreras-Campana, C., Costanza, F., Pardos, C. Diez, Dolinska, G., Eckerlin, G., Eckstein, D., Eichhorn, T., Eren, E., Gallo, E., Garcia, J. Garay, Geiser, A., Gizhko, A., Luyando, J. M. 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Abstract/Description: A search is presented for extra spatial dimensions, quantum black holes, and quark contact interactions in measurements of dijet angular distributions in proton-proton collisions at root S = 13TeV. The data were collected with the CMS detector at the LHC and correspond to an integrated luminosity of 2.6 fb(-1). The distributions are found to be in agreement with predictions from perturbative quantum chromodynamics that include electroweak corrections. Limits for di ff erent contact...
Show moreA search is presented for extra spatial dimensions, quantum black holes, and quark contact interactions in measurements of dijet angular distributions in proton-proton collisions at root S = 13TeV. The data were collected with the CMS detector at the LHC and correspond to an integrated luminosity of 2.6 fb(-1). The distributions are found to be in agreement with predictions from perturbative quantum chromodynamics that include electroweak corrections. Limits for di ff erent contact interaction models are obtained. In a benchmark model, valid to next- to- leading order in QCD and in which only left-handed quarks participate, quark contact interactions are excluded up to a scale of 11.5 and 14.7TeV for destructive or constructive interference, respectively. The production of quantum black holes is excluded for masses below 7.8 or 5.3TeV, depending on the model. The lower limits for the scales of virtual graviton exchange in the Arkani- HamedDimopoulos- Dvali model of extra spatial dimensions are in the range 7.9-11.2TeV, and are the most stringent set of limits available.
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Date Issued: 2017-07-05
Identifier: FSU_libsubv1_wos_000405104000001, 10.1007/JHEP07(2017)013
Format: Citation

Title: Search For Dark Matter Produced With An Energetic Jet Or A Hadronically Decaying W Or Z Boson At Root S=13 Tev.
Creator: Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M...
Show moreSirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schiecki, J., Strauss, J., Waltenberger, W., Wulzi, C.-E., Dvornikov, O., Makarenko, V., Mossolov, V., Gonzalez, J. Suarez, Zykunov, V., Shumeiko, N., Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., Van De Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, F., D'Hondt, J., Daci, N., De Bruyn, I., Deroover, K., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Skovpen, K., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Leonard, A., Luetic, J., Maerschalk, T., Marinov, A., Randle-conde, A., Seva, T., Vander Velde, C., Vanlaer, P., Vannerom, D., Yonamine, R., Zenoni, F., Zhang, F., Cornelis, T., Dobur, D., Fagot, A., Gul, M., Khvastunov, I., Poyraz, D., Salva, S., Schofbeck, R., Tytgat, M., Van Driessche, W., Yazgan, E., Zaganidis, N., Bakhshiansohi, H., Beluffi, C., Bondu, O., Brochet, S., Bruno, G., Caudron, A., De Visscher, S., Delaere, C., Delcourt, M., Francois, B., Giammanco, A., Jafari, A., Komm, M., Krintiras, G., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Piotrzkowski, K., Quertenmont, L., Selvaggi, M., Marono, M. Vidal, Wertz, S., Beliy, N., Alda Junior, W. L., Alves, F. L., Alves, G. A., Brito, L., Hensel, C., Moraes, A., Pol, M. E., Rebello Teles, P., Belchior Batista Das Chagas, E., Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Huertas Guativa, L. M., Malbouisson, H., Matos Figueiredo, D., Mora Herrera, C., Mundim, L., Nogima, H., Prado Da Silva, W. L., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Torres Da Silva De Araujo, F., Vilela Pereira, A., Ahuja, S., Bernardes, C. A., Dogra, S., Fernandez Perez Tomei, T. R., Gregores, E. M., Mercadante, P. C., Moon, C. S., Novaes, S. F., Padula, S., Romero Abad, D., Ruiz Vargas, J. C., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Rodozov, M., Stoykova, S., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Litov, L., Pavlov, B., Petkov, P., Fang, W., Ahmad, M., Bian, J. G., Chen, G. M., Chen, H. 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T., Jensen, F., Johnson, A., Krohn, M., Leontsinis, S., Mulholland, T., Stenson, K., Wagner, S. R., Alexander, J., Chaves, J., Chu, J., Dittmer, S., Mcdermott, K., Mirman, N., Kaufman, G. Nicolas, Patterson, J. R., Rinkevicius, A., Ryd, A., Skinnari, L., Soffi, L., Tan, S. M., Tao, Z., Thom, J., Tucker, J., Wittich, P., Zientek, M., Winn, D., Abdullin, S., Albrow, M., Apollinari, G., Apresyan, A., Banerjee, S., Bauerdick, L. A. T., Beretvas, A., Berryhill, J., Bhat, P. C., Bolla, G., Burkett, K., Butler, J. N., Cheung, H. W. K., Chlebana, F., Cihangirt, S., Cremonesi, M., Elvira, V. D., Fisk, I., Freeman, J., Gottschalk, E., Gray, L., Green, D., Grunendahl, S., Gutsche, O., Hare, D., Harris, R. M., Hasegawa, S., Hirschauer, J., Hu, Z., Jayatilaka, B., Jindariani, S., Johnson, M., Joshi, U., Klima, B., Kreis, B., Lammel, S., Linacre, J., Lincoln, D., Lipton, R., Liu, M., Liu, T., De Sa, R. Lopes, Lykken, J., Maeshima, K., Magini, N., Marraffino, J. M., Maruyama, S., Mason, D., McBride, P., Merkel, P., Mrenna, S., Nahn, S., O'Dell, V., Pedro, K., Prokofyev, O., Rakness, G., Ristori, L., Sexton-Kennedy, E., Soha, A., Spalding, W. J., Spiegel, L., Stoynev, S., Strait, J., Strobbe, N., Taylor, L., Tkaczyk, S., Tran, N. V., Uplegger, L., Vaandering, E. W., Vernieri, C., Verzocchi, M., Vidal, R., Wang, M., Weber, H. A., Whitbeck, A., Wu, Y., Acosta, D., Avery, P., Bortignon, P., Bourilkov, D., Brinkerhoff, A., Carnes, A., Carver, M., Curry, D., Das, S., Field, R. D., Furic, I. K., Konigsberg, J., Korytov, A., Low, J. F., Ma, P., Matchev, K., Mei, H., Mitselmakher, G., Rank, D., Shchutska, L., Sperka, D., Thomas, L., Wang, J., Wang, S., Yelton, J., Linn, S., Markowitz, P., Martinez, G., Rodriguez, J. L., Ackert, A., Adams, T., Askew, A., Bein, S., Hagopian, S., Hagopian, V., Johnson, K. F., Kolberg, T., Perry, T., Prosper, H., Santra, A., Yohay, R., Baarmand, M. M., Bhopatkar, V., Colafranceschi, S., Hohlmann, M., Noonan, D., Roy, T., Yumiceva, F., Adams, M. R., Apanasevich, L., Berry, D., Betts, R. R., Bucinskaite, I., Cavanaugh, R., Chen, X., Evdokimov, O., Gauthier, L., Gerber, C. E., Hangal, D. A., Hofman, D. J., Jung, K., Kamin, J., Gonzalez, I. D. Sandoval, Trauger, H., Varelas, N., Wang, H., Wu, Z., Zakaria, M., Zhang, J., Bilki, B., Clarida, W., Dilsiz, K., Durgut, S., Gandrajula, R. P., Haytmyradov, M., Khristenko, V., Merlo, J.-P., Mermerkaya, H., Mestvirishvili, A., Moeller, A., Nachtman, J., Ogul, H., Onel, Y., Ozok, F., Penzo, A., Snyder, C., Tiras, E., Wetzel, J., Yi, K., Blumenfeld, B., Cocoros, A., Eminizer, N., Fehling, D., Feng, L., Gritsan, A. V., Maksimovic, P., Roskes, J., Sarica, U., Swartz, M., Xiao, M., You, C., Al-Bataineh, A., Baringer, P., Bean, A., Boren, S., Bowen, J., Castle, J., Forthomme, L., Khalil, S., Kropivnitskaya, A., Majumder, D., Mcbrayer, W., Murray, M., Sanders, S., Stringer, R., Takaki, J. D. Tapia, Wang, Q., Ivanov, A., Kaadze, K., Maravin, Y., Mohammadi, A., Saini, L. K., Skhirtladze, N., Toda, S., Rebassoo, F., Wright, D., Anelli, C., Baden, A., Baron, O., Belloni, A., Calvert, B., Eno, S. C., Ferraioli, C., Gomez, J. A., Hadley, N. J., Jabeen, S., Jeng, G. Y., Kellogg, R. G., Kunkle, J., Mignerey, A. C., Ricci-Tam, F., Shin, Y. H., Skuja, A., Tonjes, M. B., Tonwar, S. C., Abercrombie, D., Allen, B., Apyan, A., Azzolini, V., Barbieri, R., Baty, A., Bi, R., Bierwagen, K., Brandt, S., Busza, W., Cali, I. A., D'Alfonso, M., Demiragli, Z., Ceballos, G. Gomez, Goncharov, M., Hsu, D., Iiyama, Y., Innocenti, G. M., Klute, M., Kovalskyi, D., Krajczar, K., Lai, Y. S., Lee, Y.-J., Levin, A., Luckey, P. D., Maier, B., Marini, A. C., Mcginn, C., Mironov, C., Narayanan, S., Niu, X., Paus, C., Roland, C., Roland, G., Salfeld-Nebgen, J., Stephans, G. S. F., Tatar, K., Velicanu, D., Wang, J., Wang, T. W., Wyslouch, B., Benvenuti, A. C., Chatterjee, R. M., Evans, A., Hansen, P., Kalafut, S., Kao, S. C., Kubota, Y., Lesko, Z., Mans, J., Nourbakhsh, S., Ruckstuhl, N., Rusack, R., Tambe, N., Turkewitz, J., Acosta, J. G., Oliveros, S., Avdeeva, E., Bloom, K., Claes, D. R., Fangmeier, C., Suarez, R. Gonzalez, Kamalieddin, R., Kravchenko, I., Rodrigues, A. Malta, Monroy, J., Siado, J. E., Snow, G. R., Stieger, B., Alyari, M., Dolen, J., Godshalk, A., Harrington, C., Iashvili, I., Kaisen, J., Nguyen, D., Parker, A., Rappoccio, S., Roozbahani, B., Alverson, G., Barberis, E., Hortiangtham, A., Massironi, A., Morse, D. M., Nash, D., Orimoto, T., De Lima, R. Teixeira, Trocino, D., Wang, R.-J., Wood, D., Bhattacharya, S., Charaf, O., Hahn, K. A., Kumar, A., Mucia, N., Odell, N., Pollack, B., Schmitt, M. H., Sung, K., Trovato, M., Velasco, M., Dev, N., Hildreth, M., Anampa, K. Hurtado, Jessop, C., Karmgard, D. J., Kellams, N., Lannon, K., Marinelli, N., Meng, F., Mueller, C., Musienko, Y., Planer, M., Reinsvold, A., Ruchti, R., Rupprecht, N., Smith, G., Taroni, S., Wayne, M., Wolf, M., Woodard, A., Alimena, J., Antonelli, L., Bylsma, B., Durkin, L. S., Flowers, S., Francis, B., Hart, A., Hill, C., Ji, W., Liu, B., Luo, W., Puigh, D., Winer, B. L., Wulsin, H. W., Cooperstein, S., Driga, O., Elmer, P., Hardenbrook, J., Hebda, P., Lange, D., Luo, J., Marlow, D., Medvedeva, T., Mei, K., Ojalvo, I., Olsen, J., Palmer, C., Piroue, P., Stickland, D., Svyatkovskiy, A., Tully, C., Malik, S., Barker, A., Barnes, V. E., Folgueras, S., Gutay, L., Jha, M. K., Jones, M., Jung, A. W., Khatiwada, A., Miller, D. H., Neumeister, N., Schulte, J. F., Shi, X., Sun, J., Wang, F., Xie, W., Parashar, N., Stupak, J., Adair, A., Akgun, B., Chen, Z., Ecklund, K. M., Geurts, F. J. M., Guilbaud, M., Li, W., Michlin, B., Northup, M., Padley, B. P., Roberts, J., Rorie, J., Tu, Z., Zabel, J., Betchart, B., Bodek, A., de Barbaro, P., Demina, R., Duh, Y. t, Ferbel, T., Galanti, M., Garcia-Bellido, A., Han, J., Hindrichs, O., Khukhunaishvili, A., Lo, K. H., Tan, P., Verzetti, M., Agapitos, A., Chou, J. P., Gershtein, Y., Espinosa, T. A. Gomez, Halkiadakis, E., Heindl, M., Hughes, E., Kaplan, S., Elayavalli, R. Kunnawalkam, Kyriacou, S., Lath, A., Nash, K., Osherson, M., Saka, H., Salur, S., Schnetzer, S., Sheffield, D., Somalwar, S., Stone, R., Thomas, S., Thomassen, P., Walker, M., Delannoy, A. G., Foerster, M., Heideman, J., Riley, G., Rose, K., Spanier, S., Thapa, K., Bouhali, O., Celik, A., Dalchenko, M., De Mattia, M., Delgado, A., Dildick, S., Eusebi, R., Gilmore, J., Huang, T., Juska, E., Kamon, T., Mueller, R., Pakhotin, Y., Patel, R., Perloff, A., Pernie, L., Rathjens, D., Safonov, A., Tatarinov, A., Ulmer, K. A., Akchurin, N., Damgov, J., De Guio, F., Dragoiu, C., Dudero, P. R., Faulkner, J., Gurpinar, E., Kunori, S., Lamichhane, K., Lee, S. W., Libeiro, T., Peltola, T., Undleeb, S., Volobouev, I., Wang, Z., Greene, S., Gurrola, A., Janjam, R., Johns, W., Maguire, C., Melo, A., Ni, H., Sheldon, P., Tuo, S., Velkovska, J., Xu, Q., Arenton, M. W., Barria, P., Cox, B., Goodell, J., Hirosky, R., Ledovskoy, A., Li, H., Neu, C., Sinthuprasith, T., Sun, X., Wang, Y., Wolfe, E., Xia, F., Clarke, C., Harr, R., Karchin, P. E., Sturdy, J., Zaleski, S., Belknap, D. A., Buchanan, J., Caillol, C., Dasu, S., Dodd, L., Duric, S., Comber, B., Grothe, M., Herndon, M., Herve, A., Hussain, U., Klabbers, P., Lanaro, A., Levine, A., Long, K., Loveless, R., Pierro, G. A., Polese, G., Ruggles, T., Savin, A., Smith, N., Smith, W. H., Taylor, D., Woods, N.
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Abstract/Description: A search for dark matter particles is performed using events with large missing transverse momentum, at least one energetic jet, and no leptons, in proton-proton collisions at root S = 13TeV collected with the CMS detector at the LHC. The data sample corresponds to an integrated luminosity of 12.9 fb(-1). The search includes events with jets from the hadronic decays of a W or Z boson. The data are found to be in agreement with the predicted background contributions from standard model...
Show moreA search for dark matter particles is performed using events with large missing transverse momentum, at least one energetic jet, and no leptons, in proton-proton collisions at root S = 13TeV collected with the CMS detector at the LHC. The data sample corresponds to an integrated luminosity of 12.9 fb(-1). The search includes events with jets from the hadronic decays of a W or Z boson. The data are found to be in agreement with the predicted background contributions from standard model processes. The results are presented in terms of simpli fi ed models in which dark matter particles are produced through interactions involving a vector, axial-vector, scalar, or pseudoscalar mediator. Vector and axial-vector mediator particles with masses up to 1.95TeV, and scalar and pseudoscalar mediator particles with masses up to 100 and 430 GeV respectively, are excluded at 95% con fi dence level. The results are also interpreted in terms of the invisible decays of the Higgs boson, yielding an observed (expected) 95% con fi dence level upper limit of 0.44 (0.56) on the corresponding branching fraction. The results of this search provide the strongest constraints on the dark matter pair production cross section through vector and axial-vector mediators at a particle collider. When compared to the direct detection experiments, the limits obtained from this search provide stronger constraints for dark matter masses less than 5, 9, and 550 GeV, assuming vector, scalar, and axial-vector mediators, respectively. The search yields stronger constraints for dark matter masses less than 200 GeV, assuming a pseudoscalar mediator, when compared to the indirect detection results from Fermi-LAT.
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Date Issued: 2017-07-05
Identifier: FSU_libsubv1_wos_000405104000002, 10.1007/JHEP07(2017)014
Format: Citation

Title: Modeling the early language trajectory of language development and its relation to poor reading comprehension.
Creator: Petscher, Yaacov, Justice, Laura, Hogan, Tiffany, Mashburn, Andrew
Abstract/Description: This study examined change in early language comprehension from 15 to 54 months for fifth grade typical readers (n = 35), poor decoders (n = 11), or poor comprehenders (n = 16) who were ascertained at birth in 1991 in a nationally representative study of early child-care experiences. Measures of language comprehension were captured across early childhood for the 72 children, and these measures changed at each measurement time-point; therefore, data were transformed to ranks. Multiple group...
Show moreThis study examined change in early language comprehension from 15 to 54 months for fifth grade typical readers (n = 35), poor decoders (n = 11), or poor comprehenders (n = 16) who were ascertained at birth in 1991 in a nationally representative study of early child-care experiences. Measures of language comprehension were captured across early childhood for the 72 children, and these measures changed at each measurement time-point; therefore, data were transformed to ranks. Multiple group quasi-simplex and latent growth models were used to examine children’s relative rank change. Results showed that future poor comprehenders significantly declined in language comprehension over time relative to future poor decoders and typical readers, who gradually improved. Findings suggest that deficits in early language contribute to reading difficulties. Efforts to improve language skills as a means to improve reading comprehension, particularly for poor comprehenders, hinge upon the perspective that language weaknesses are a causal contributor to reading difficulties.
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Date Issued: 2017-07-05
Identifier: FSU_libsubv1_scholarship_submission_1490109631, 10.1111/cdev.12880
Format: Citation

Title: The M(6)a Pathway Facilitates Sex Determination In Drosophila.
Creator: Kan, Lijuan, Grozhik, Anya V., Vedanayagam, Jeffrey, Patil, Deepak P., Pang, Nan, Lim, Kok-Seong, Huang, Yi-Chun, Joseph, Brian, Lin, Ching-Jung, Despic, Vladimir, Guo, Jian,...
Show moreKan, Lijuan, Grozhik, Anya V., Vedanayagam, Jeffrey, Patil, Deepak P., Pang, Nan, Lim, Kok-Seong, Huang, Yi-Chun, Joseph, Brian, Lin, Ching-Jung, Despic, Vladimir, Guo, Jian, Yan, Dong, Kondo, Shu, Deng, Wu-Min, Dedon, Peter C., Jaffrey, Samie R., Lai, Eric C.
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Abstract/Description: The conserved modification N-6-methyladenosine (m(6)A) modulates mRNA processing and activity. Here, we establish the Drosophila system to study the m(6)A pathway. We first apply miCLIP to map m(6)A across embryogenesis, characterize its m(6)A 'writer' complex, validate its YTH 'readers' CG6422 and YT521-B, and generate mutants in five m(6)A factors. While m(6)A factors with additional roles in splicing are lethal, m(6)A-specific mutants are viable but present certain developmental and...
Show moreThe conserved modification N-6-methyladenosine (m(6)A) modulates mRNA processing and activity. Here, we establish the Drosophila system to study the m(6)A pathway. We first apply miCLIP to map m(6)A across embryogenesis, characterize its m(6)A 'writer' complex, validate its YTH 'readers' CG6422 and YT521-B, and generate mutants in five m(6)A factors. While m(6)A factors with additional roles in splicing are lethal, m(6)A-specific mutants are viable but present certain developmental and behavioural defects. Notably, m(6)A facilitates the master female determinant Sxl, since multiple m(6)A components enhance female lethality in Sxl sensitized backgrounds. The m(6)A pathway regulates Sxl processing directly, since miCLIP data reveal Sxl as a major intronic m(6)A target, and female-specific Sxl splicing is compromised in multiple m(6)A pathway mutants. YT521-B is a dominant m(6)A effector for Sxl regulation, and YT521-B overexpression can induce female-specific Sxl splicing. Overall, our transcriptomic and genetic toolkit reveals in vivo biologic function for the Drosophila m(6)A pathway.
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Date Issued: 2017-07-04
Identifier: FSU_libsubv1_wos_000404640800001, 10.1038/ncomms15737
Format: Citation

Title: Search For Associated Production Of A Z Boson With A Single Top Quark And For Tz Flavour-changing Interactions In Pp Collisions At Root S=8 Tev.
Creator: Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M...
Show moreSirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schieck, J., Strauss, J., Waltenberger, W., Wulzi, C.-E., Dvornikov, O., Makarenko, V., Mossolov, V., Gonzalez, J. Suarez, Zykunov, V., Shumeiko, N., Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., Van De Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, F., D'Hondt, J., Daci, N., De Bruyn, I., Deroover, K., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Skovpen, K., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Leonard, A., Luetic, J., Maer-Schalk, T., Marinov, A., Randle-Conde, A., Seva, T., Velde, C. Vander, Vanlaer, P., Vannerom, D., Yonamine, R., Zenoni, F., Zhang, F., Cimmino, A., Cornelis, T., Dobur, D., Fagot, A., Gul, M., Khvastunov, I., Poyraz, D., Salva, S., Schofbeck, R., Tytgat, M., Van Driessche, W., Yazgan, E., Zaganidis, N., Bakhshiansohi, H., Beluffi, C., Bondu, O., Brochet, S., Bruno, G., Caudron, A., De Visscher, S., Delaere, C., Delcourt, M., Francois, B., Giammanco, A., Jafari, A., Komm, M., Krintiras, G., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Piotrzkowski, K., Quertenmont, L., Selvaggi, M., Marono, M. Vidal, Wertz, S., Beliy, N., Aida Junior, W. L., Alves, F. L., Alves, G. A., Brito, L., Hensel, C., Moraes, A., Pol, M. E., Rebello Teles, P., Das Chagas, E. Belchior Batista, Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Huertas Guativa, L. M., Malbouisson, H., Matos Figueiredo, D., Mora Herrera, C., Mundim, L., Nogima, H., Prado Da Silva, W. L., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Vilela Pereira, A., Ahuja, S., Bernardes, C. A., Dogra, S., Tomei, T. R. Fernandez Perez, Gregores, E. M., Mercadante, P. C., Moon, C. S., Novaes, S. F., Padulaa, Sandra S., Romero Abad, D., Ruiz Vargas, J. C., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Rodozov, M., Stoykova, S., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Litov, L., Pavlov, B., Petkov, P., Fang, W., Ahmad, M., Bian, J. G., Chen, G. M., Chen, H. S., Chen, M., Chen, Y., Cheng, T., Jiang, C. H., Leggat, D., Liu, Z., Romeo, F., Ruan, M., Shaheen, S. M., Spiezia, A., Tao, J., Wang, C., Wang, Z., Zhang, H., Zhao, J., Ban, Y., Chen, G., Li, Q., Liu, S., Mao, Y., Qian, S. J., Wang, D., Xu, Z., Avila, C., Cabrera, A., Chaparro Sierra, L. F., Florez, C., Gomez, J. P., Gonzalez Hernandez, C. F., Ruiz Alvarez, J. D., Sanabria, J. C., Godinovic, N., Lelas, D., Puljak, I., Cipriano, P. M. Ribeiro, Sculac, T., Antunovic, Z., Kovac, M., Brigljevic, V., Ferencek, D., Kadija, K., Mesic, B., Susa, T., Attikis, A., Mavromanolakis, G., Mousa, J., Nicolaou, C., Ptochos, F., Razis, P. A., Rykaczewski, H., Tsiakkouri, D., Fingers, M., Finger, M., Carrera Jarrin, E., Kamel, A. Ellithi, Mahmoud, M. A., Radi, A., Kadastik, M., Perrini, L., Raidal, M., Tiko, A., Veelken, C., Eerola, P., Pekkanen, J., Voutilainen, M., Harkonen, J., Jarvinen, T., Karimaki, V., Kinnunen, R., Lampen, T., Lassila-Perini, K., Lehti, S., Linden, T., Luukka, P., Tuominiemi, J., Tuovinen, E., Wendland, L., Talvitie, J., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Fabbro, B., Faure, J. L., Favaro, C., Ferri, F., Ganjour, S., Ghosh, S., Givernaud, A., Gras, P., de Monchenault, G. Hamel, Jarry, P., Kucher, I., Locci, E., Machet, M., Maleles, J., Rander, J., Rosowsky, A., Titov, M., Abdulsalam, A., Antropov, I., Baffioni, S., Beaudette, F., Busson, P., Cadamuro, L., Chapon, E., Charlot, C., Davignon, O., de Cassagnac, R. Granier, Lisniak, M. Jo S., Mine, P., Nguyen, M., Ochando, C., Ortona, G., Paganini, P., Pigard, P., Regnard, S., Salerno, R., Sirois, Y., Strebler, T., Yilmaz, Y., Zabi, A., Zghiche, A., Agram, J.-L., Andrea, J., Aubin, A., Bloch, D., Brom, J.-M., Buttignol, M., Chabert, E. C., Chanon, N., Collard, C., Conte, E., Coubez, X., Fontaine, J.-C., Gele, D., Goerlach, U., Le Bihan, A.-C., Van Hove, P., Gadrat, S., Beauceron, S., Bernet, C., Boudoul, G., Montoya, C. A. Carrillo, Chierici, R., Contardo, D., Courbon, B., Depasse, P., El Mamouni, H., Fay, J., Gascon, S., Gouzevitch, M., Grenier, G., Ille, B. J. O. Y., Lagarde, F., Laktineh, I. B., Lethuillier, M., Mirabito, L., Pequegnot, A. L., Perries, S., Popov, A., Sabes, D., Sordini, V., Donckt, M. 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Abstract/Description: A search for the production of a single top quark in association with a Z boson is presented, both to identify the expected standard model process and to search for flavour changing neutral current interactions. The data sample corresponds to an integrated luminosity of 19.7 fb(-1) recorded by the CMS experiment at the LHC in proton-proton collisions at root s = 8 TeV. Final states with three leptons (electrons or muons) and at least one jet are investigated. An events yield compatible with...
Show moreA search for the production of a single top quark in association with a Z boson is presented, both to identify the expected standard model process and to search for flavour changing neutral current interactions. The data sample corresponds to an integrated luminosity of 19.7 fb(-1) recorded by the CMS experiment at the LHC in proton-proton collisions at root s = 8 TeV. Final states with three leptons (electrons or muons) and at least one jet are investigated. An events yield compatible with tZq standard model production is observed, and the corresponding cross section is measured to be sigma(pp -> tZq -> lvbl(+)l(-) q) = 10(-7)(+8) fb with a significance of 2.4 standard deviations. No presence of flavour-changing neutral current production of tZq is observed. Exclusion limits at 95% confidence level on the branching fractions of a top quark decaying to a Z boson and an up or a charm quark are found to be B(t -> Zu) < 0.022% and B(t -> Zc) < 0.049%.
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Date Issued: 2017-07-03
Identifier: FSU_libsubv1_wos_000405103900001, 10.1007/JHEP07(2017)003
Format: Citation

Title: Search For T(t)over-bar Resonances In Highly Boosted Lepton Plus Jets And Fully Hadronic Final States In Proton-proton Collisions At Root S=13 Tev.
Creator: Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M...
Show moreSirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schieck, J., Strauss, J., Waltenberger, W., Wulz, C.-E., Chekhovsky, V., Mossolov, V., Gonzalez, J. Suarez, Shumeiko, N., Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., Van de Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, F., D'Hondt, J., De Bruyn, I., De Clercq, J., Deroover, K., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Skovpen, K., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Luetic, J., Maerschalk, T., Marinov, A., Randle-Conde, A., Seva, T., Velde, C. Vander, Vanlaer, P., Vannerom, D., Yonamine, R., Zenoni, F., Zhang, F., Cimmino, A., Cornelis, T., Dobur, D., Fagot, A., Gul, M., Khvastunov, I., Poyraz, D., Salva, S., Schofbeck, R., Tytgat, M., Van Driessche, W., Verbeke, W., Zaganidis, N., Bakhshiansohi, H., Bondu, O., Brochet, S., Bruno, G., Caudron, A., De Visscher, S., Delaere, C., Delcourt, M., Francois, B., Giammanco, A., Jafari, A., Komm, M., Krintiras, G., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Piotrzkowski, K., Quertenmont, L., Marono, M. Vidal, Wertz, S., Beliy, N., Alda Junior, W. L., Alves, F. L., Alves, G. A., Brito, L., Hensel, C., Moraes, A., Pol, M. E., Rebello Teles, P., Belchior Batista Das Chagas, E., Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., Fonseca De Souza, S., Huertas Guativa, L. M., Malbouisson, H., Mora Herrera, C., Mundim, L., Nogima, H., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Torres Da Silva De Araujo, F., Vilela Pereira, A., Ahuja, S., Bernardes, C. A., Fernandez Perez Tomei, T. R., Gregore, E. M., Mercadante, P. G., Moon, C. S., Novaes, S. F., Padula, Sandra S., Romero Abad, D., Ruiz Vargas, J. C., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Rodozov, M., Stoykova, S., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Litov, L., Pavlov, B., Petkov, P., Fang, W., Gao, X., Ahmad, M., Bian, J. G., Chen, G. M., Chen, H. S., Chen, M., Chen, Y., Jiang, C. H., Leggat, D., Liu, Z., Romeo, F., Shaheen, S. M., Spiezia, A., Tao, J., Wang, C., Wang, Z., Zhang, H., Zhao, J., Ban, Y., Chen, G., Li, Q., Liu, S., Mao, Y., Qian, S. J., Wang, D., Xu, Z., Avila, C., Cabrera, A., Chaparro Sierra, L. F., Florez, C., Gomez, J. P., Gonzalez Hernandez, C. F., Ruiz Alvarez, J. D., Godinovic, N., Lelas, D., Puljak, I., Cipriano, P. M. Ribeiro, Sculac, T., Antunovic, Z., Kovac, M., Brigljevic, V., Ferencek, D., Kadija, K., Mesic, B., Susa, T., Ather, M. 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M., Richards, A., Rose, A., Scott, E., Seez, C., Summers, S., Tapper, A., Uchida, K., Acosta, M. Vazquez, Virdee, T., Wright, J., Zenz, S. C., Cole, J. E., Hobson, P. R., Khan, A., Kyberd, P., Reid, I. D., Symonds, P., Teodorescu, L., Turner, M., Borzou, A., Call, K., Dittmann, J., Hatakeyama, K., Liu, H., Pastika, N., Bartek, R., Dominguez, A., Buccilli, A., Cooper, S. I., Henderson, C., Rumerio, P., West, C., Arcaro, D., Avetisyan, A., Bose, T., Gastler, D., Rankin, D., Richardson, C., Rohlf, J., Sulak, L., Zou, D., Benelli, G., Cutts, D., Garabedian, A., Hakala, J., Heintz, U., Hogan, J. M., Kwok, K. H. M., Laird, E., Landsberg, G., Mao, Z., Narain, M., Piperov, S., Sagir, S., Spencer, E., Syarif, R., Burns, D., Sanchez, M. Calderon De La Barca, Chertok, M., Conway, J., Conway, R., Cox, P. T., Erbacher, R., Flores, C., Funk, G., Gardner, M., Ko, W., Lander, R., Mclean, C., Mulhearn, M., Pellett, D., Pilot, J., Shalhout, S., Shi, M., Smith, J., Squires, M., Stolp, D., Tos, K., Tripathi, M., Bachtis, M., Bravo, C., Cousins, R., Dasgupta, A., Florent, A., Hauser, J., Ignatenko, M., Mccoll, N., Saltzberg, D., Schnaible, C., Valuev, V., Bouvier, E., Burt, K., Clare, R., Ellison, J., Gary, J. W., Shirazi, S. M. A. Ghiasi, Hanson, G., Heilman, J., Jandir, P., Kennedy, E., Lacroix, F., Long, O. R., Negrete, M. Olmedo, Paneva, M. I., Shrinivas, A., Si, W., Wei, H., Wimpenny, S., Yates, B. R., Branson, J. G., Cerati, G. B., Cittolin, S., Derdzinski, M., Holzner, A., Klein, D., Kole, G., Krutelyov, V., Letts, J., Macneill, I., Olivito, D., Padhi, S., Pieri, M., Sani, M., Sharma, V., Simon, S., Tadel, M., Vartak, A., Wasserbaech, S., Wurthwein, F., Yagil, A., Della Porta, G. Zevi, Amin, N., Bhandari, R., Bradmiller-Feld, J., Campagnari, C., Dishaw, A., Dutta, V., Sevilla, M. Franco, George, C., Golf, F., Gouskos, L., Gran, J., Heller, R., Incandela, J., Mullin, S. D., Ovcharova, A., Qu, H., Richman, J., Stuart, D., Suarez, I., Yoo, J., Anderson, D., Bendavid, J., Bornheim, A., Lawhorn, J. M., Newman, H. B., Pena, C., Spiropulu, M., Vlimant, J. R., Xie, S., Zhu, R. Y., Andrews, M. B., Ferguson, T., Paulini, M., Russ, J., Sun, M., Vogel, H., Vorobiev, I., Weinberg, M., Cumalat, J. P., Ford, W. T., Jensen, F., Johnson, A., Krohn, M., Leontsinis, S., Mulholland, T., Stenson, K., Wagner, S. R., Alexander, J., Chaves, J., Chu, J., Dittmer, S., Mcdermott, K., Mirman, N., Patterson, J. R., Rinkevicius, A., Ryd, A., Skinnari, L., Soffi, L., Tan, S. M., Tao, Z., Thom, J., Tucker, J., Wittich, P., Zientek, M., Winn, D., Abdullin, S., Albrow, M., Apollinari, G., Apresyan, A., Banerjee, S., Bauerdick, L. A. T., Beretvas, A., Berryhill, J., Bhat, P. C., Bolla, G., Burkett, K., Butler, J. N., Canepa, A., Cheung, H. W. K., Chlebana, F., Cremonesi, M., Duarte, J., Elvira, V. D., Fisk, I., Freeman, J., Gecse, Z., Gottschalk, E., Gray, L., Green, D., Grunendahl, S., Gutsche, O., Harris, R. M., Hasegawa, S., Hirschauer, J., Hu, Z., Jayatilaka, B., Jindariani, S., Johnson, M., Joshi, U., Klima, B., Kreis, B., Lammel, S., Lincoln, D., Lipton, R., Liu, M., Liu, T., De Sa, R. Lopes, Lykken, J., Maeshima, K., Magini, N., Marraffino, J. M., Maruyama, S., Mason, D., McBride, P., Merkel, P., Mrenna, S., Nahn, S., O'Dell, V., Pedro, K., Prokofyev, O., Rakness, G., Ristori, L., Schneider, B., Sexton-Kennedy, E., Soha, A., Spalding, W. J., Spiegel, L., Stoynev, S., Strait, J., Strobbe, N., Taylor, L., Tkaczyk, S., Tran, N. V., Uplegger, L., Vaandering, E. W., Vernieri, C., Verzocchi, M., Vidal, R., Wang, M., Weber, H. A., Whitbeck, A., Acosta, D., Avery, P., Bortignon, P., Brinkerhoff, A., Carnes, A., Carver, M., Curry, D., Das, S., Field, R. D., Furic, I. K., Konigsberg, J., Korytov, A., Kotov, K., Ma, P., Matchev, K., Mei, H., Mitselmakher, G., Rank, D., Shchutska, L., Sperka, D., Terentyev, N., Thomas, L., Wang, J., Wang, S., Yelton, J., Linn, S., Markowitz, P., Martinez, G., Rodriguez, J. L., Ackert, A., Adams, T., Askew, A., Bein, S., Hagopian, S., Hagopian, V., Johnson, K. F., Kolberg, T., Perry, T., Prosper, H., Santra, A., Yohay, R., Baarmand, M. M., Bhopatkar, V., Colafranceschi, S., Hohlmann, M., Noonan, D., Roy, T., Yumiceva, F., Adams, M. R., Apanasevich, L., Berry, D., Betts, R. R., Cavanaugh, R., Chen, X., Evdokimov, O., Gerber, C. E., Hangal, D. A., Hofman, D. J., Jung, K., Kamin, J., Gonzalez, I. D. Sandoval, Tonjes, M. B., Trauger, H., Varelas, N., Wang, H., Wu, Z., Zhang, J., Bilki, B., Clarida, W., Dilsiz, K., Durgut, S., Gandrajula, R. P., Haytmyradov, M., Khristenko, V., Merlo, J.-P., Mermerkaya, H., Mestvirishvili, A., Moeller, A., Nachtman, J., Ogul, H., Onel, Y., Ozok, F., Penzo, A., Snyder, C., Tiras, E., Wetzel, J., Yi, K., Blumenfeld, B., Cocoros, A., Eminizer, N., Fehling, D., Feng, L., Gritsan, A. V., Maksimovic, P., Roskes, J., Sarica, U., Swartz, M., Xiao, M., You, C., Al-Bataineh, A., Baringer, P., Bean, A., Boren, S., Bowen, J., Castle, J., Khalil, S., Kropivnitskaya, A., Majumder, D., Mcbrayer, W., Murray, M., Royon, C., Sanders, S., Stringer, R., Takaki, J. D. Tapia, Wang, Q., Ivanov, A., Kaadze, K., Maravin, Y., Mohammadi, A., Saini, L. K., Skhirtladze, N., Toda, S., Rebassoo, F., Wright, D., Anelli, C., Baden, A., Baron, O., Belloni, A., Calvert, B., Eno, S. C., Ferraioli, C., Hadley, N. J., Jabeen, S., Jeng, G. Y., Kellogg, R. G., Kunkle, J., Mignerey, A. C., Ricci-Tam, F., Shin, Y. H., Skuja, A., Tonwar, S. C., Abercrombie, D., Allen, B., Apyan, A., Azzolini, V., Barbieri, R., Baty, A., Bi, R., Bierwagen, K., Brandt, S., Busza, W., Cali, I. A., D'Alfonso, M., Demiragli, Z., Ceballos, G. Gomez, Goncharov, M., Hsu, D., Iiyama, Y., Innocenti, G. M., Klute, M., Kovalskyi, D., Lai, Y. S., Lee, Y.-J., Levin, A., Luckey, P. D., Maier, B., Marini, A. C., Mcginn, C., Mironov, C., Narayanan, S., Niu, X., Paus, C., Roland, C., Roland, G., Salfeld-Nebgen, J., Stephans, G. S. F., Tatar, K., Velicanu, D., Wang, J., Wang, T. W., Wyslouch, B., Benvenuti, A. C., Chatterjee, R. M., Evans, A., Hansen, P., Kalafut, S., Kao, S. C., Kubota, Y., Lesko, Z., Mans, J., Nourbakhsh, S., Ruckstuhl, N., Rusack, R., Tambe, N., Turkewitz, J., Acosta, J. G., Oliveros, S., Avdeeva, E., Bloom, K., Claes, D. R., Fangmeier, C., Suarez, R. Gonzalez, Kamalieddin, R., Kravchenko, I., Monroy, J., Siado, J. E., Snow, G. R., Stieger, B., Alyari, M., Dolen, J., Godshalk, A., Harrington, C., Iashvili, I., Kharchilava, A., Parker, A., Rappoccio, S., Roozbahani, B., Alverson, G., Barberis, E., Hortiangtham, A., Massironi, A., Morse, D. M., Nash, D., Orimoto, T., De Lima, R. Teixeira, Trocino, D., Wang, R.-J., Wood, D., Bhattacharya, S., Charaf, O., Hahn, K. A., Mucia, N., Odell, N., Pollack, B., Schmitt, M. H., Sung, K., Trovato, M., Velasco, M., Dev, N., Hildreth, M., Anampa, K. Hurtado, Jessop, C., Karmgard, D. J., Kellams, N., Lannon, K., Loukas, N., Marinelli, N., Meng, F., Mueller, C., Musienko, Y., Planer, M., Reinsvold, A., Ruchti, R., Rupprecht, N., Smith, G., Taroni, S., Wayne, M., Wolf, M., Woodard, A., Alimena, J., Antonelli, L., Bylsma, B., Durkin, L. S., Flowers, S., Francis, B., Hart, A., Hill, C., Ji, W., Liu, B., Luo, W., Puigh, D., Winer, B. L., Wulsin, H. W., Benaglia, A., Cooperstein, S., Driga, O., Elmer, P., Hardenbrook, J., Hebda, P., Lange, D., Luo, J., Marlow, D., Mei, K., Ojalvo, I., Olsen, J., Palmer, C., Piroue, P., Stickland, D., Svyatkovskiy, A., Tully, C., Malik, S., Norberg, S., Barker, A., Barnes, V. E., Folgueras, S., Gutay, L., Jha, M. K., Jones, M., Jung, A. W., Khatiwada, A., Miller, D. H., Neumeister, N., Schulte, J. F., Sun, J., Wang, F., Xie, W., Cheng, T., Parashar, N., Stupak, J., Adair, A., Akgun, B., Chen, Z., Ecklund, K. M., Geurts, F. J. M., Guilbaud, M., Li, W., Michlin, B., Northup, M., Padley, B. P., Roberts, J., Rorie, J., Tu, Z., Zabel, J., Betchart, B., Bodek, A., de Barbaro, P., Demina, R., Duh, Y. t, Ferbel, T., Galanti, M., Garcia-Bellido, A., Han, J., Hindrichs, O., Khukhunaishvili, A., Lo, K. H., Tan, P., Verzetti, M., Ciesielski, R., Goulianos, K., Mesropian, C., Agapitos, A., Chou, J. P., Gershtein, Y., Espinosa, T. A. Gomez, Halkiadakis, E., Heindl, M., Hughes, E., Kaplan, S., Elayavalli, R. Kunnawalkam, Kyriacou, S., Lath, A., Montalvo, R., Nash, K., Osherson, M., Saka, H., Salur, S., Schnetzer, S., Sheffield, D., Somalwar, S., Stone, R., Thomas, S., Thomassen, P., Walker, M., Foerster, M., Heideman, J., Riley, G., Rose, K., Spanier, S., Thapa, K., Bouhali, O., Hernandez, A. Castaneda, Celik, A., Dalchenko, M., De Mattia, M., Delgado, A., Dildick, S., Eusebi, R., Gilmore, J., Huang, T., Kamon, T., Mueller, R., Pakhotin, Y., Patel, R., Perloff, A., Pernie, L., Rathjens, D., Safonov, A., Tatarinov, A., Ulmer, K. A., Akchurin, N., Damgov, J., De Guio, F., Dragoiu, C., Dudero, P. R., Faulkner, J., Gurpinar, E., Kunori, S., Lamichhane, K., Lee, S. W., Libeiro, T., Peltola, T., Undleeb, S., Volobouev, I., Wang, Z., Greene, S., Gurrola, A., Janjam, R., Johns, W., Maguire, C., Melo, A., Ni, H., Sheldon, P., Tuo, S., Velkovska, J., Xu, Q., Arenton, M. W., Barria, P., Cox, B., Hirosky, R., Ledovskoy, A., Li, H., Neu, C., Sinthuprasith, T., Sun, X., Wang, Y., Wolfe, E., Xia, F., Clarke, C., Harr, R., Karchin, P. E., Sturdy, J., Zaleski, S., Belknap, D. A., Buchanan, J., Caillol, C., Dasu, S., Dodd, L., Duric, S., Gomber, B., Grothe, M., Herndon, M., Herve, A., Hussain, U., Klabbers, P., Lanaro, A., Levine, A., Long, K., Loveless, R., Pierro, G. A., Polese, G., Ruggles, T., Savin, A., Smith, N., Smith, W. H., Taylor, D., Woods, N.
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Abstract/Description: A search for the production of heavy resonances decaying into top quark-antiquark pairs is presented. The analysis is performed in the lepton+jets and fully hadronic channels using data collected in proton-proton collisions at root s = 13 TeV using the CMS detector at the LHC, corresponding to an integrated luminosity of 2.6 fb(-1). The selection is optimized for massive resonances, where the top quarks have large Lorentz boosts. No evidence for resonant t (t) over bar production is found in...
Show moreA search for the production of heavy resonances decaying into top quark-antiquark pairs is presented. The analysis is performed in the lepton+jets and fully hadronic channels using data collected in proton-proton collisions at root s = 13 TeV using the CMS detector at the LHC, corresponding to an integrated luminosity of 2.6 fb(-1). The selection is optimized for massive resonances, where the top quarks have large Lorentz boosts. No evidence for resonant t (t) over bar production is found in the data, and upper limits on the production cross section of heavy resonances are set. The exclusion limits for resonances with masses above 2 TeV are significantly improved compared to those of previous analyses at root s = 8 TeV.
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Date Issued: 2017-07-03
Identifier: FSU_libsubv1_wos_000405103700001, 10.1007/JHEP07(2017)001
Format: Citation

Title: Exploring Background Mutational Processes To Decipher Cancer Genetic Heterogeneity.
Creator: Goncearenco, Alexander, Rager, Stephanie L., Li, Minghui, Sang, Qing-Xiang, Rogozin, Igor B., Panchenko, Anna R.
Abstract/Description: Much remains unknown about the progression and heterogeneity of mutational processes in different cancers and their diagnostic and clinical potential. A growing body of evidence supports mutation rate dependence on the local DNA sequence context for various types of mutations. We propose several tools for the analysis of cancer context-dependent mutations, which are implemented in an online computational framework MutaGene. The framework explores DNA context-dependent mutational patterns and...
Show moreMuch remains unknown about the progression and heterogeneity of mutational processes in different cancers and their diagnostic and clinical potential. A growing body of evidence supports mutation rate dependence on the local DNA sequence context for various types of mutations. We propose several tools for the analysis of cancer context-dependent mutations, which are implemented in an online computational framework MutaGene. The framework explores DNA context-dependent mutational patterns and underlying somatic cancer mutagenesis, analyzes mutational profiles of cancer samples, identifies the combinations of underlying mutagenic processes including those related to infidelity of DNA replication and repair machinery, and various other endogenous and exogenous mutagenic factors. As a result, the combination of mutagenic processes can be identified in any query sample with subsequent comparison to mutational profiles derived from malignant and benign samples. In addition, mutagen or cancer-specific mutational background models are applied to calculate expected DNA and protein site mutability to decouple relative contributions of mutagenesis and selection in carcinogenesis, thus elucidating the site-specific driving events in cancer. MutaGene is freely available at https://www.ncbi.nlm.nih.gov/projects/mutagene/.
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Date Issued: 2017-07-03
Identifier: FSU_libsubv1_wos_000404427000078, 10.1093/nar/gkx367
Format: Citation

Title: An Rfid-based Smart Structure For The Supply Chain: Resilient Scanning Proofs And Ownership Transfer With Positive Secrecy Capacity Channels.
Creator: Burmester, Mike, Munilla, Jorge, Ortiz, Andres, Caballero-Gil, Pino
Abstract/Description: The National Strategy for Global Supply Chain Security published in 2012 by the White House identifies two primary goals for strengthening global supply chains: first, to promote the efficient and secure movement of goods, and second to foster a resilient supply chain. The Internet of Things (IoT), and in particular Radio Frequency Identification (RFID) technology, can be used to realize these goals. For product identification, tracking and real-time awareness, RFID tags are attached to goods...
Show moreThe National Strategy for Global Supply Chain Security published in 2012 by the White House identifies two primary goals for strengthening global supply chains: first, to promote the efficient and secure movement of goods, and second to foster a resilient supply chain. The Internet of Things (IoT), and in particular Radio Frequency Identification (RFID) technology, can be used to realize these goals. For product identification, tracking and real-time awareness, RFID tags are attached to goods. As tagged goods move along the supply chain from the suppliers to the manufacturers, and then on to the retailers until eventually they reach the customers, two major security challenges can be identified: (I) to protect the shipment of goods that are controlled by potentially untrusted carriers; and (II) to secure the transfer of ownership at each stage of the chain. For the former, grouping proofs in which the tags of the scanned goods generate a proof of simulatenous presence can be employed, while for the latter, ownership transfer protocols (OTP) are used. This paper describes enhanced security solutions for both challenges. We first extend earlier work on grouping proofs and group codes to capture resilient group scanning with untrusted readers; then, we describe a modified version of a recently published OTP based on channels with positive secrecy capacity adapted to be implemented on common RFID systems in the supply chain. The proposed solutions take into account the limitations of low cost tags employed in the supply chain, which are only required to generate pseudorandom numbers and compute one-way hash functions.
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Date Issued: 2017-07
Identifier: FSU_libsubv1_wos_000407517600101, 10.3390/s17071562
Format: Citation

Title: Semidiurnal Internal Tide Incoherence In The Equatorial Pacific.
Creator: Buijsman, Maarten C., Arbic, Brian K., Richman, James G., Shriver, Jay F., Wallcraft, Alan J., Zamudio, Luis
Abstract/Description: The jets in the equatorial Pacific Ocean of a realistically forced global circulation model with a horizontal resolution of 1/12.5 degrees cause a strong loss of phase coherence in semidiurnal internal tides that propagate equatorward from the French Polynesian Islands and Hawaii. This loss of coherence is quantified with a baroclinic energy analysis, in which the semidiurnal-band terms are separated into coherent, incoherent, and cross terms. For time scales longer than a year, the coherent...
Show moreThe jets in the equatorial Pacific Ocean of a realistically forced global circulation model with a horizontal resolution of 1/12.5 degrees cause a strong loss of phase coherence in semidiurnal internal tides that propagate equatorward from the French Polynesian Islands and Hawaii. This loss of coherence is quantified with a baroclinic energy analysis, in which the semidiurnal-band terms are separated into coherent, incoherent, and cross terms. For time scales longer than a year, the coherent energy flux approaches zero values at the equator, while the total flux is similar to 500 W/m. The time variability of the incoherent energy flux is compared with the internal-tide travel-time variability, which is based on along-beam integrated phase speeds computed with the Taylor-Goldstein equation. The variability of monthly mean Taylor-Goldstein phase speeds agrees well with the phase speed variability inferred from steric sea surface height phases extracted with a plane-wave fit technique. On monthly time scales, the loss of phase coherence in the equatorward beams from the French Polynesian Islands is attributed to the time variability in the vertically sheared background flow associated with the jets and tropical instability waves. On an annual time scale, the effect of stratification variability is of equal or greater importance than the shear variability is to the loss of coherence. In the model simulations, low-frequency equatorial jets do not noticeably enhance the dissipation of the internal tide, but merely decohere and scatter it.
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Date Issued: 2017-07
Identifier: FSU_libsubv1_wos_000409893600005, 10.1002/2016JC012590
Format: Citation

Title: Using Automation And Batch Processing To Remediate Duplicate Series Data In A Shared Bibliographic Catalog.
Creator: Dong, Elaine, Glerum, Margaret Anne, Fenichel, Ethan
Abstract/Description: The application of divergent local practices in a shared bibliographic database can result in unexpected display issues that adversely affect user experience. This is especially problematic when merging databases from multiple institutions accustomed to adopting local practices for their own constituents. The authors describe their experience with the application of automation tools, such as MarcEdit, Excel, and Python, during a large-scale remediation project. They used these tools to...
Show moreThe application of divergent local practices in a shared bibliographic database can result in unexpected display issues that adversely affect user experience. This is especially problematic when merging databases from multiple institutions accustomed to adopting local practices for their own constituents. The authors describe their experience with the application of automation tools, such as MarcEdit, Excel, and Python, during a large-scale remediation project. They used these tools to analyze, compare, and batch process bibliographic records to remediate obsolete and redundant series data in their shared bibliographic database.
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Date Issued: 2017-07
Identifier: FSU_libsubv1_wos_000407484000004
Format: Citation

Title: Upregulation Of An Inward Rectifying K+ Channel Can Rescue Slow Ca2+ Oscillations In K (atp) Channel Deficient Pancreatic Islets.
Creator: Yildirim, Vehpi, Vadrevu, Suryakiran, Thompson, Benjamin, Satin, Leslie S., Bertram, Richard
Abstract/Description: Plasma insulin oscillations are known to have physiological importance in the regulation of blood glucose. In insulin-secreting beta-cells of pancreatic islets, K(ATP) channels play a key role in regulating glucose-dependent insulin secretion. In addition, they convey oscillations in cellular metabolism to the membrane by sensing adenine nucleotides, and are thus instrumental in mediating pulsatile insulin secretion. Blocking K(ATP) channels pharmacologically depolarizes the beta-cell plasma...
Show morePlasma insulin oscillations are known to have physiological importance in the regulation of blood glucose. In insulin-secreting beta-cells of pancreatic islets, K(ATP) channels play a key role in regulating glucose-dependent insulin secretion. In addition, they convey oscillations in cellular metabolism to the membrane by sensing adenine nucleotides, and are thus instrumental in mediating pulsatile insulin secretion. Blocking K(ATP) channels pharmacologically depolarizes the beta-cell plasma membrane and terminates islet oscillations. Surprisingly, when K(ATP) channels are genetically knocked out, oscillations in islet activity persist, and relatively normal blood glucose levels are maintained. Compensation must therefore occur to overcome the loss of K(ATP) channels in K(ATP) knockout mice. In a companion study, we demonstrated a substantial increase in Kir2.1 protein occurs in beta-cells lacking K(ATP) because of SUR1 deletion. In this report, we demonstrate that beta-cells of SUR1 null islets have an upregulated inward rectifying K+ current that helps to compensate for the loss of K (ATP) channels. This current is likely due to the increased expression of Kir2.1 channels. We used mathematical modeling to determine whether an ionic current having the biophysical characteristics of Kir2.1 is capable of rescuing oscillations that are similar in period to those of wild-type islets. By experimentally testing a key model prediction we suggest that Kir2.1 current upregulation is a likely mechanism for rescuing the oscillations seen in islets from mice deficient in K(ATP) channels.
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Date Issued: 2017-07
Identifier: FSU_libsubv1_wos_000406619800052, 10.1371/journal.pcbi.1005686
Format: Citation

Title: Polarimetry Of The Superluminous Supernova Lsq14mo: No Evidence For Significant Deviations From Spherical Symmetry (vol 815, Pg L17, 2017).
Creator: Leloudas, Giorgos, Patat, Ferdinando, Maund, Justyn R., Hsiao, Eric, Malesani, Daniele, Schulze, Steve, Contreras, Carlos, de Ugarte Postigo, Antonio, Sollerman, Jesper,...
Show moreLeloudas, Giorgos, Patat, Ferdinando, Maund, Justyn R., Hsiao, Eric, Malesani, Daniele, Schulze, Steve, Contreras, Carlos, de Ugarte Postigo, Antonio, Sollerman, Jesper, Stritzinger, Maximilian D., Taddia, Francesco, Wheeler, J. Craig, Gorosabel, Javier
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Date Issued: 2017-07-01
Identifier: FSU_libsubv1_wos_000404908700001
Format: Citation

Title: Changes on the Ground: Site Visit Report of the Third Year of Developmental Education Reform in the Florida College System.
Creator: Hu, Shouping, Bertrand Jones, Tamara, Bower, Rebecca, Park, Toby, Nix, Amanda, Rahming, Sophia, Harrison, Jamaal, Sermon, Jenay, Daniels, Hollie
Abstract/Description: Researchers at the CPS have been conducting a longitudinal study of how Florida College System (FCS) institutions have implemented developmental education reform (SB 1720) on their campuses. As a part of this research report, CPS researchers conducted site visits to nine FCS institutions from November 2016 to April 2017. In this statewide report, we consider administrative, faculty, advisor, support staff, and student perspectives on broad trends which have taken place across the FCS since SB...
Show moreResearchers at the CPS have been conducting a longitudinal study of how Florida College System (FCS) institutions have implemented developmental education reform (SB 1720) on their campuses. As a part of this research report, CPS researchers conducted site visits to nine FCS institutions from November 2016 to April 2017. In this statewide report, we consider administrative, faculty, advisor, support staff, and student perspectives on broad trends which have taken place across the FCS since SB 1720 was enacted. We begin this report by presenting perceptions of the legislation we encountered across the state of Florida in 2016-2017 by stakeholders at nine institutions.
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Date Issued: 2017-07-01
Identifier: FSU_libsubv1_scholarship_submission_1502900193_fd9ec2bd, 10.17125/fsu.1502900193
Format: Citation

Title: Sport Spectatorship And Life Satisfaction: A Multicountry Investigation.
Creator: Inoue, Yuhei, Sato, Mikihiro, Filo, Kevin, Du, James, Funk, Daniel C.
Abstract/Description: Elite and professional sport events have been recognized as potential mechanisms to enhance well-being. This multicountry study investigates how engagement in such events, behaviorally through live spectating and psychologically through team identification, is associated with life satisfaction. Data from Australia (N=268) revealed a positive association between live spectating and life satisfaction through a two-wave design measuring live spectating and life satisfaction in separate surveys....
Show moreElite and professional sport events have been recognized as potential mechanisms to enhance well-being. This multicountry study investigates how engagement in such events, behaviorally through live spectating and psychologically through team identification, is associated with life satisfaction. Data from Australia (N=268) revealed a positive association between live spectating and life satisfaction through a two-wave design measuring live spectating and life satisfaction in separate surveys. Data from the United States (N=564) confirmed the live spectating life satisfaction relationship found in Study 1. Additionally, Study 2 revealed individuals with higher levels of team identification perceived greater emotional support from other fans, and this perception, in turn, predicted life satisfaction. Our findings provide sport managers with implications for positioning appeals in support of sport programs and designing events that facilitate engagement to promote life satisfaction in the community.
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Date Issued: 2017-07
Identifier: FSU_libsubv1_wos_000405761700008, 10.1123/jsm.2016-0295
Format: Citation

Title: Assessing Early Elementary Students' Place Value Understanding: A Set of Interview Tasks.
Creator: Bray, Wendy S., Champagne, Zachary M., Blais, Tanya Vik, Schoen, Robert C.
Abstract/Description: This document contains a set of materials we created, selected, or adapted for the purpose of assessing children’s understanding of place value. These materials were sequenced to form a diagnostic assessment for use in a one-on-one, interview-type setting. The resulting collection of tasks and questions require approximately 20–30 minutes to administer with an individual child. The assessment is designed for diagnostic purposes. It is not intended to generate an achievement score.
Date Issued: 2017-06-30
Identifier: FSU_libsubv1_scholarship_submission_1510066800_57c75c1b, 10.17125/fsu.1510066800
Format: Citation

Title: Polar Rotor Scattering As Atomic-level Origin Of Low Mobility And Thermal Conductivity Of Perovskite Ch3nh3pbi3.
Creator: Li, Bing, Kawakita, Yukinobu, Liu, Yucheng, Wang, Mingchao, Matsuura, Masato, Shibata, Kaoru, Ohira-Kawamura, Seiko, Yamada, Takeshi, Lin, Shangchao, Nakajima, Kenji, Liu,...
Show moreLi, Bing, Kawakita, Yukinobu, Liu, Yucheng, Wang, Mingchao, Matsuura, Masato, Shibata, Kaoru, Ohira-Kawamura, Seiko, Yamada, Takeshi, Lin, Shangchao, Nakajima, Kenji, Liu, Shengzhong
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Abstract/Description: Perovskite CH3NH3PbI3 exhibits outstanding photovoltaic performances, but the understanding of the atomic motions remains inadequate even though they take a fundamental role in transport properties. Here, we present a complete atomic dynamic picture consisting of molecular jumping rotational modes and phonons, which is established by carrying out high-resolution time-of-flight quasi-elastic and inelastic neutron scattering measurements in a wide energy window ranging from 0.0036 to 54 meV on...
Show morePerovskite CH3NH3PbI3 exhibits outstanding photovoltaic performances, but the understanding of the atomic motions remains inadequate even though they take a fundamental role in transport properties. Here, we present a complete atomic dynamic picture consisting of molecular jumping rotational modes and phonons, which is established by carrying out high-resolution time-of-flight quasi-elastic and inelastic neutron scattering measurements in a wide energy window ranging from 0.0036 to 54 meV on a large single crystal sample, respectively. The ultrafast orientational disorder of molecular dipoles, activated at similar to 165 K, acts as an additional scattering source for optical phonons as well as for charge carriers. It is revealed that acoustic phonons dominate the thermal transport, rather than optical phonons due to sub-picosecond lifetimes. These microscopic insights provide a solid standing point, on which perovskite solar cells can be understood more accurately and their performances are perhaps further optimized.
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Date Issued: 2017-06-30
Identifier: FSU_libsubv1_wos_000404455400001, 10.1038/ncomms16086
Format: Citation

Title: Coulomb-interaction Induced Coupling Of Landau Levels In Intrinsic And Modulation-doped Quantum Wells.
Creator: Paul, J., Stevens, C. E., Zhang, H., Dey, P., McGinty, D., McGill, S. A., Smith, R. P., Reno, J. L., Turkowski, V., Perakis, I. E., Hilton, D. J., Karaiskaj, D.
Abstract/Description: We have performed two- dimensional Fourier transform spectroscopy on intrinsic and modulation doped quantum wells in external magnetic fields up to 10 T. In the undoped sample, the strong Coulomb interactions and the increasing separations of the electron and hole charge distributions with increasing magnetic fields lead to a nontrivial in-plane dispersion of the magneto-excitons. Thus, the discrete and degenerate Landau levels are coupled to a continuum. The signature of this continuum is...
Show moreWe have performed two- dimensional Fourier transform spectroscopy on intrinsic and modulation doped quantum wells in external magnetic fields up to 10 T. In the undoped sample, the strong Coulomb interactions and the increasing separations of the electron and hole charge distributions with increasing magnetic fields lead to a nontrivial in-plane dispersion of the magneto-excitons. Thus, the discrete and degenerate Landau levels are coupled to a continuum. The signature of this continuum is the emergence of elongated spectral line shapes at the Landau level energies, which are exposed by the multidimensional nature of our technique. Surprisingly, the elongation of the peaks is completely absent in the lowest Landau level spectra obtained from the modulation doped quantum well at high fields.
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Date Issued: 2017-06-28
Identifier: FSU_libsubv1_wos_000404469700004, 10.1103/PhysRevB.95.245314
Format: Citation

Title: Measurement Of Electroweak-induced Production Of W Gamma With Two Jets In Pp Collisions At Root S=8tev And Constraints On Anomalous Quartic Gauge Couplings.
Creator: Khachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth...
Show moreKhachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Asilar, E., Bergauer, T., Brandstetter, J., Brondolin, E., Dragicevic, M., Eroe, J., Flechl, M., Friedl, M., Fruehwirth, R., Ghete, V. M., Hartl, C., Hoermann, N., Hrubec, J., Jeitler, M., Koenig, A., Kraetschmer, I., Liko, D., Matsushita, T., Mikulec, I., Rabady, D., Rad, N., Rahbaran, B., Rohringer, H., Schieckl, J., Strauss, J., Treberer-Treberspurg, W., Waltenberger, W., Wulz, C.-E., Mossolov, V., Shumeiko, N., Gonzalez, J. Suarez, Alderweireldt, S., De Wolf, E. A., Janssen, X., Lauwers, J., Van de Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Van Spilbeeck, A., Abu Zeid, S., Blekman, F., D'Hondt, J., Daci, N., De Bruyn, I., Deroover, K., Heracleous, N., Lowette, S., Moortgat, S., Moreels, L., Olbrechts, A., Python, Q., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Brun, H., Caillol, C., Clerbaux, B., De Lentdecker, G., Delannoy, H., Fasanella, G., Favart, L., Goldouzian, R., Grebenyuk, A., Karapostoli, G., Lenzi, T., Leonard, A., Luetic, J., Maerschalk, T., Marinov, A., Randle-conde, A., Seva, T., Vander Velde, C., Vanlaer, P., Yonamine, R., Zenoni, F., Zhang, F., Cimmino, A., Cornelis, T., Dobur, D., Fagot, A., Garcia, G., Gul, M., Poyraz, D., Salva, S., Schofbeck, R., Tytgat, M., Van Driessche, W., Yazgan, E., Zaganidis, N., Bakhshiansohi, H., Beluffi, C., Bondu, O., Brochet, S., Bruno, G., Caudron, A., De Visscher, S., Delaere, C., Delcourt, M., Francois, B., Giammanco, A., Jafari, A., Jez, P., Komm, M., Lemaitre, V., Magitteri, A., Mertens, A., Musich, M., Nuttens, C., Piotrzkowski, K., Quertenmont, L., Selvaggi, M., Marono, M. Vidal, Wertz, S., Beliy, N., Aida Junior, W. L., Alves, F. L., Alves, G. A., Brito, L., Hensel, C., Moraes, A., Pol, M. E., Rebello Teles, P., Belchior Batista Das Chagas, E., Carvalho, W., Chinellato, J., Custodio, A., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Huertas Guativa, L. M., Malbouisson, H., Matos Figueiredo, D., Mora Herrera, C., Mundim, L., Nogima, H., Prado Da Silva, W. L., Santoro, A., Sznajder, A., Tonelli Manganote, E. J., Vilela Pereira, A., Ahuja, S., Bernardes, C. A., Dogra, S., Fernandez Perez Tomei, T. R., Gregores, E. M., Mercadante, P. C., Moon, C. S., Novaes, S. F., Padula, Sandra S., Romero Abad, D., Ruiz Vargas, J. C., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Rodozov, M., Stoykova, S., Sultanov, G., Vutova, M., Dimitrov, A., Glushkov, I., Litov, L., Pavlov, B., Petkov, P., Fang, W., Ahmad, M., Bian, J. G., Chen, G. M., Chen, H. S., Chen, M., Chen, Y., Cheng, T., Jiang, C. H., Leggat, D., Liu, Z., Romeo, F., Shaheen, S. M., Spiezia, A., Tao, J., Wang, C., Wang, Z., Zhang, H., Zhao, J., Ban, Y., Chen, G., Li, Q., Liu, S., Mao, Y., Qian, S. J., Wang, D., Xu, Z., Yang, D., Zhang, Z., Avila, C., Cabrera, A., Chaparro Sierra, L. F., Florez, C., Gomez, J. P., Gonzalez Hernandez, C. F., Ruiz Alvarez, J. D., Sanabria, J. C., Godinovic, N., Lelas, D., Puljak, I., Cipriano, P. M. Ribeiro, Sculac, T., Antunovic, Z., Kovac, M., Brigljevic, V., Ferencek, D., Kadija, K., Micanovic, S., Sudic, L., Susa, T., Attikis, A., Mavromanolakis, G., Mousa, J., Nicolaou, C., Ptochos, F., Razis, P. A., Rykaczewski, H., Finger, M., Finger, M., Carrera Jarrin, E., Abdelalim, A. A., Mohammed, Y., Salama, E., Calpas, B., Kadastik, M., Murumaa, M., Perrini, L., Raidal, M., Tiko, A., Veelken, C., Eerola, P., Pekkanen, J., Voutilainen, M., Harkonen, J., Karimaki, V., Kinnunen, R., Lampen, T., Lassila-Perini, K., Lehti, S., Linden, T., Luukka, P., Peltola, T., Tuominiemi, J., Tuovinen, E., Wendland, L., Talvitie, J., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Fabbro, B., Faure, J. L., Favaro, C., Ferri, F., Ganjour, S., Ghosh, S., Givernaud, A., Gras, P., de Monchenault, G. Hamel, Jarry, P., Kucher, I., Locci, E., Machet, M., Maleles, J., Rander, J., Rosowsky, A., Titov, M., Zghiche, A., Abdulsalam, A., Antropov, I., Baffioni, S., Beaudette, F., Busson, P., Cadamuro, L., Chapon, E., Charlot, C., Davignon, O., de Cassagnac, R. Granier, Jo, M., Lisniak, S., Mine, P., Nguyen, M., Ochando, C., Ortona, G., Paganini, P., Pigard, P., Regnard, S., Salerno, R., Sirois, Y., Strebler, T., Yilmaz, Y., Zabi, A., Agram, J.-L., Andrea, J., Aubin, A., Bloch, D., Brom, J.-M., Buttignol, M., Chabert, E. C., Chanon, N., Collard, C., Conte, E., Coubez, X., Fontaine, J.-C., Gele, D., Goerlach, U., Le Bihan, A.-C., Merlin, J. A., Skovpen, K., Van Hove, P., Gadrat, S., Beauceron, S., Bernet, C., Boudoul, G., Bouvier, E., Montoya, C. A. Carrillo, Chierici, R., Contardo, D., Courbon, B., Depasse, P., El Mamouni, H., Fan, J., Fay, J., Gascon, S., Gouzevitch, M., Grenier, G., Ille, B., Lagarde, F., Laktineh, I. B., Lethuillier, M., Mirabito, L., Pequegnot, A. L., Perries, S., Popov, A., Sabes, D., Sordini, V., Vander Donckt, M., Verdier, P., Viret, S., Khvedelidze, A., Tsamalaidze, Z., Autermann, C., Beranek, S., Feld, L., Heister, A., Kiesel, M. K., Klein, K., Lipinski, M., Ostapchuk, A., Preuten, M., Raupach, F., Schael, S., Schomakers, C., Schulte, J. F., Schulz, J., Verlage, T., Weber, H., Zhukov, V., Brodski, M., Dietz-Laursonn, E., Duchardt, D., Endres, M., Erdmann, M., Erdweg, S., Esch, T., Fischer, R., Gueth, A., Hamer, M., Hebbeker, T., Heidemann, C., Hoepfner, K., Knutzen, S., Merschmeyer, M., Meyer, A., Millet, P., Mukherjee, S., Olschewski, M., Padeken, K., Pook, T., Radziej, M., Reithler, H., Rieger, M., Scheuch, F., Sonnenschein, L., Teyssier, D., Thueer, S., Cherepanov, V., Fluegge, G., Ahmad, W. Haj, Hoehle, F., Kargoll, B., Kress, T., Kuensken, A., Lingemann, J., Mueller, T., Nehrkorn, A., Nowack, A., Nugent, I. M., Pistone, C., Pooth, O., Stahl, A., Martin, M. Aldaya, Asawatangtrakuldee, C., Beernaert, K., Behnke, O., Behrens, U., Bin Anuar, A. A., Borras, K., Campbell, A., Connor, P., Contreras-Campana, C., Costanza, F., Pardos, C. Diez, Dolinska, G., Eckerlin, G., Eckstein, D., Eren, E., Gallo, E., Garcia, J. Garay, Geiser, A., Gizhko, A., Luyando, J. M. Grados, Gunnellini, P., Harb, A., Hauk, J., Hempel, M., Jung, H., Kalogeropoulos, A., Karacheban, O., Kasemann, M., Keaveney, J., Kieseler, J., Kleinwort, C., Korol, I., Kruecker, D., Lange, W., Lelek, A., Leonard, J., Lipka, K., Lobanov, A., Lohmann, W., Mankel, R., Melzer-Pellmann, I.-A., Meyer, A. B., Mittag, G., Mnich, J., Mussgiller, A., Ntomari, E., Pitzl, D., Placakyte, R., Raspereza, A., Roland, B., Sahin, M. O., Saxena, P., Schoerner-Sadenius, T., Seitz, C., Spannagel, S., Stefaniuk, N., Trippkewitz, K. D., Van Onsem, G. P., Walsh, R., Wissing, C., Blobel, V., Vignali, M. Centis, Draeger, A. R., Dreyer, T., Garutti, E., Gonzalez, D., Haller, J., Hoffmann, M., Junkes, A., Klanner, R., Kogler, R., Kovalchuk, N., Lapsien, T., Lenz, T., Marchesini, I., Marconi, D., Meyer, M., Niedziela, M., Nowatschin, D., Pantaleo, F., Peiffer, T., Perieanu, A., Poehlsen, J., Sander, C., Scharf, C., Schleper, P., Schmidt, A., Schumann, S., Schwandt, J., Stadie, H., Steinbrueck, G., Stober, F. M., Stoever, M., Tholen, H., Troendle, D., Usai, E., Vanelderen, L., Vanhoefer, A., Vormwald, B., Barth, C., Baus, C., Berger, J., Butz, E., Chwalek, T., Colombo, F., De Boer, W., Dierlamm, A., Fink, S., Friese, R., Giffels, M., Gilbert, A., Goldenzweig, P., Haitz, D., Hartmann, F., Heindl, S. M., Husemann, U., Katkov, I., Pardo, P. Lobelle, Maier, B., Mildner, H., Mozer, M. U., Mueller, Th, Plagge, M., Quast, G., Rabbertz, K., Roecker, S., Roscher, F., Schroeder, M., Shvetsov, I., Sieber, G., Simonis, H. J., Ulrich, R., Wagner-Kuhr, J., Wayand, S., Weber, M., Weiler, T., Williamson, S., Woehrmann, C., Wolf, R., Anagnostou, G., Daskalakis, G., Geralis, T., Giakoumopoulou, V. A., Kyriakis, A., Loukas, D., Topsis-Giotis, I., Agapitos, A., Kesisoglou, S., Panagiotou, A., Saoulidou, N., Tziaferi, E., Evangelou, I., Flouris, G., Foudas, C., Kokkas, P., Loukas, N., Manthos, N., Papadopoulos, I., Paradas, E., Filipovic, N., Bencze, G., Hajdu, C., Hidas, P., Horvath, D., Sikler, F., Veszpremi, V., Vesztergombi, G., Zsigmond, A. J., Beni, N., Czellar, S., Karancsi, J., Makovec, A., Molnar, J., Szillasi, Z., Bartok, M., Raics, P., Trocsanyi, Z. L., Ujvari, B., Bahinipati, S., Choudhury, S., Mal, P., Mandal, K., Nayak, A., Sahoo, D. K., Sahoo, N., Swain, S. K., Bansal, S., Beri, S. B., Bhatnagar, V., Chawla, R., Bhawandeep, U., Kalsi, A. K., Kaur, A., Kaur, M., Kumar, R., Mehta, A., Mittal, M., Singh, J. B., Walia, G., Kumar, Ashok, Bhardwaj, A., Choudhary, B. C., Garg, R. B., Keshri, S., Malhotra, S., Naimuddin, M., Nishu, N., Ranjan, K., Sharma, R., Sharma, V., Bhattacharya, R., Bhattacharya, S., Chatterjee, K., Dey, S., Dutt, S., Dutta, S., Ghosh, S., Majumdar, N., Modak, A., Mondal, K., Mukhopadhyay, S., Nandan, S., Purohit, A., Roy, A., Roy, D., Chowdhury, S. Roy, Sarkar, S., Sharan, M., Thakur, S., Behera, P. K., Chudasama, R., Dutta, D., Jha, V., Kumar, V., Mohanty, A. K., Netrakanti, P. K., Pant, L. M., Shukla, P., Topkar, A., Aziz, T., Dugad, S., Kole, G., Mahakud, B., Mitra, S., Mohanty, G. B., Parida, B., Sur, N., Sutar, B., Banerjee, S., Bhowmik, S., Dewanjee, R. K., Ganguly, S., Guchait, M., Jain, Sa, Kumar, S., Maity, M., Majumder, G., Mazumdar, K., Sarkar, T., Wickramage, N., Chauhan, S., Dube, S., Hegde, V., Kapoor, A., Kothekar, K., Rane, A., Sharma, S., Behnamian, H., Chenarani, S., Tadavani, E. Eskandari, Etesami, S. M., Fahim, A., Khakzad, M., Najafabadi, M. Mohammadi, Naseri, M., Mehdiabadi, S. Paktinat, Hosseinabadi, F. Rezaei, Safarzadeh, B., Zeinali, M., Felcini, M., Grunewald, M., Abbrescia, M., Calabria, C., Caputo, C., Colaleo, A., Creanza, D., Cristella, L., De Filippis, N., De Palma, M., Fiore, L., Iaselli, G., Maggi, G., Maggi, M., Miniello, G., My, S., Nuzzo, S., Pompili, A., Pugliese, G., Radogna, R., Ranieri, A., Selvaggi, G., Silvestris, L., Venditti, R., Verwilligen, P., Abbiendi, G., Battilana, C., Bonacorsi, D., Braibant-Giacomelli, S., Brigliadori, L., Campanini, R., Capiluppi, P., Castro, A., Cavallo, F. R., Chhibra, S. S., Codispoti, G., Cuffiani, M., Dallavalle, G. M., Fabbri, F., Fanfani, A., Fasanella, D., Giacomelli, P., Grandi, C., Guiducci, L., Marcellini, S., Masetti, G., Montanari, A., Navarria, F. L., Perrotta, A., Rossi, A. M., Rovelli, T., Siroli, G. P., Tosi, N., Albergo, S., Chiorboli, M., Costa, S., Di Mattia, A., Giordano, F., Potenza, R., Tricomi, A., Tuve, C., Barbagli, G., Ciulli, V., Civinini, C., D'Alessandro, R., Focardi, E., Gori, V., Lenzi, P., Meschini, M., Paoletti, S., Sguazzoni, G., Viliani, L., Benussi, L., Bianco, S., Fabbri, F., Piccolo, D., Primavera, F., Calvelli, V., Ferro, F., Lo Vetere, M., Monge, M. R., Robutti, E., Tosi, S., Brianza, L., Dinardo, M. E., Fiorendi, S., Gennai, S., Ghezzi, A., Govoni, P., Malberti, M., Malvezzi, S., Manzoni, R. A., Marzocchi, B., Menasce, D., Moroni, L., Paganoni, M., Pedrini, D., Pigazzini, S., Ragazzi, S., de Fatis, T. Tabarelli, Buontempo, S., Cavallo, N., De Nardo, G., Di Guida, S., Esposito, M., Fabozzi, F., Iorio, A. O. M., Lanza, G., Lista, L., Meola, S., Paolucci, P., Sciacca, C., Thyssen, F., Azzi, P., Bacchetta, N., Benato, L., Bisello, D., Boletti, A., Carlin, R., De Oliveira, A. Carvalho Antunes, Checchia, P., Dall'Osso, M., Manzano, P. De Castro, Dorigo, T., Dosselli, U., Gasparini, F., Gasparini, U., Gozzelino, A., Lacaprara, S., Margoni, M., Meneguzzo, A. T., Pazzini, J., Pozzobon, N., Ronchese, P., Simonetto, F., Torassa, E., Zanetti, M., Zotto, P., Zucchetta, A., Zumerle, G., Braghieri, A., Magnani, A., Montagna, P., Ratti, S. P., Re, V., Riccardi, C., Salvini, P., Vai, I., Vitulo, P., Solestizi, L. Alunni, Bilei, G. M., Ciangottini, D., Fano, L., Lariccia, P., Leonardi, R., Mantovani, G., Menichelli, M., Saha, A., Santocchia, A., Androsov, K., Azzurri, P., Bagliesi, G., Bernardini, J., Boccali, T., Castaldi, R., Ciocci, M. A., Dell'Orso, R., Donato, S., Fedi, G., Giassi, A., Grippo, M. T., Ligabue, F., Lomtadze, T., Martini, L., Messineo, A., Palla, F., Rizzi, A., Savoy-Navarro, A., Spagnolo, P., Tenchini, R., Tonelli, G., Venturi, A., Verdini, P. G., Barone, L., Cavallari, F., Cipriani, M., D'imperio, G., Del Re, D., Diemoz, M., Gelli, S., Jorda, C., Longo, E., Margaroli, F., Meridiani, P., Organtini, G., Paramatti, R., Preiato, F., Rahatlou, S., Rovelli, C., Santanastasio, F., Amapane, N., Arcidiacono, R., Argiro, S., Arneodo, M., Bartosik, N., Bellan, R., Biino, C., Cartiglia, N., Cenna, F., Costa, M., Covarelli, R., Degano, A., Demaria, N., Finco, L., Kiani, B., Mariotti, C., Maselli, S., Migliore, E., Monaco, V., Monteil, E., Obertino, M. M., Pacher, L., Pastrone, N., Pelliccioni, M., Angioni, G. L. Pinna, Ravera, F., Romero, A., Ruspa, M., Sacchi, R., Shchelina, K., Sola, V., Solano, A., Staiano, A., Traczyk, P., Belforte, S., Casarsa, M., Cossutti, F., Della Ricca, G., La Licata, C., Schizzi, A., Zanetti, A., Kim, D. H., Kim, G. N., Kim, M. S., Lee, S., Lee, S. W., Oh, Y. D., Sekmen, S., Son, D. C., Yang, Y. C., Lee, A., Cifuentes, J. A. Brochero, Kim, T. J., Cho, S., Choi, S., Go, Y., Gyun, D., Ha, S., Hong, B., Jo, Y., Kim, Y., Lee, B., Lee, K., Lee, K. S., Lee, S., Lim, J., Park, S. K., Roh, Y., Almond, J., Kim, J., Lee, H., Oh, S. B., Radburn-Smith, B. C., Seo, S. H., Yang, U. K., Yoo, H. D., Yu, G. B., Choi, M., Kim, H., Kim, H., Kim, J. H., Lee, J. S. H., Park, I. C., Ryu, G., Ryu, M. S., Choi, Y., Goh, J., Hwang, C., Lee, J., Yu, I., Dudenas, V., Juodagalvis, A., Vaitkus, J., Ahmed, I., Ibrahim, Z. A., Komaragiri, J. R., Ali, M. A. B. Md, Idris, F. Mohamad, Abdullah, W. A. T. Wan, Yusli, M. N., Zolkapli, Z., Castilla-Valdez, H., De La Cruz-Burelo, E., Heredia-De La Cruz, I., Hernandez-Almada, A., Lopez-Fernandez, R., Magana Villalba, R., Mejia Guisao, J., Sanchez-Hernandez, A., Carrillo Moreno, S., Oropeza Barrera, C., Vazquez Valencia, F., Carpinteyro, S., Pedraza, I., Salazar Ibarguen, H. A., Uribe Estrada, C., Morelos Pineda, A., Krofcheck, D., Butler, P. H., Ahmad, A., Ahmad, M., Hassan, Q., Hoorani, H. R., Khan, W. 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V., Moisenz, P., Palichik, V., Perelygin, V., Shmatov, S., Shulha, S., Skatchkov, N., Smirnov, V., Tikhonenko, E., Voytishin, N., Zarubin, A., Chtchipounov, L., Golovtsov, V., Ivanov, Y., Kim, V., Kuznetsova, E., Murzin, V., Oreshkin, V., Sulimov, V., Vorobyev, A., Andreev, Yu, Dermenev, A., Gninenko, S., Golubev, N., Karneyeu, A., Kirsanov, M., Krasnikov, N., Pashenkov, A., Tlisov, D., Toropin, A., Epshteyn, V., Gavrilov, V., Lychkovskaya, N., Popov, V., Pozdnyakov, I., Safronov, G., Spiridonov, A., Toms, M., Vlasov, E., Zhokin, A., Bylinkin, A., Chadeeva, M., Popova, E., Tarkovskii, E., Andreev, V., Azarkin, M., Dremin, I., Kirakosyan, M., Leonidov, A., Rusakov, S. 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Abstract/Description: A measurement of electroweak-induced production of W gamma and two jets is performed, where the W boson decays leptonically. The data used in the analysis correspond to an integrated luminosity of 19.7 fb(-1) collected by the CMS experiment in root s = 8TeV proton-proton collisions produced at the LHC. Candidate events are selected with exactly one muon or electron, missing transverse momentum, one photon, and two jets with large rapidity separation. An excess over the hypothesis of the...
Show moreA measurement of electroweak-induced production of W gamma and two jets is performed, where the W boson decays leptonically. The data used in the analysis correspond to an integrated luminosity of 19.7 fb(-1) collected by the CMS experiment in root s = 8TeV proton-proton collisions produced at the LHC. Candidate events are selected with exactly one muon or electron, missing transverse momentum, one photon, and two jets with large rapidity separation. An excess over the hypothesis of the standard model without electroweak production of W gamma with two jets is observed with a signi fi cance of 2.7 standard deviations. The cross section measured in the fi ducial region is 10.8 +/- 4.1(stat) +/- 3.4(syst) +/- 0. 3(lumi) fb, which is consistent with the standard model electroweak prediction. The total cross section for W gamma in association with two jets in the same fi ducial region is measured to be 23.2 +/- 4.3(stat) +/- 1.7(syst) +/- 0.6(lumi) fb, which is consistent with the standard model prediction from the combination of electroweakand quantum chromodynamics-induced processes. No deviations are observed from the standard model predictions and experimental limits on anomalous quartic gauge couplings integral M,0- 7 /Lambda(4), integral T,0- 2 /Lambda(4), and integral T,5-7/Lambda(4) are set at 95% con fi dence level.
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Date Issued: 2017-06-20
Identifier: FSU_libsubv1_wos_000404141800007, 10.1007/JHEP06(2017)106
Format: Citation

Title: International Society of Sports Nutrition Position Stand: protein and exercise..
Creator: Jäger, Ralf, Kerksick, Chad M, Campbell, Bill I, Cribb, Paul J, Wells, Shawn D, Skwiat, Tim M, Purpura, Martin, Ziegenfuss, Tim N, Ferrando, Arny A, Arent, Shawn M, Smith-Ryan,...
Show moreJäger, Ralf, Kerksick, Chad M, Campbell, Bill I, Cribb, Paul J, Wells, Shawn D, Skwiat, Tim M, Purpura, Martin, Ziegenfuss, Tim N, Ferrando, Arny A, Arent, Shawn M, Smith-Ryan, Abbie E, Stout, Jeffrey R, Arciero, Paul J, Ormsbee, Michael J, Taylor, Lem W, Wilborn, Colin D, Kalman, Doug S, Kreider, Richard B, Willoughby, Darryn S, Hoffman, Jay R, Krzykowski, Jamie L, Antonio, Jose
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Abstract/Description: The International Society of Sports Nutrition (ISSN) provides an objective and critical review related to the intake of protein for healthy, exercising individuals. Based on the current available literature, the position of the Society is as follows:An acute exercise stimulus, particularly resistance exercise, and protein ingestion both stimulate muscle protein synthesis (MPS) and are synergistic when protein consumption occurs before or after resistance exercise.For building muscle mass and...
Show moreThe International Society of Sports Nutrition (ISSN) provides an objective and critical review related to the intake of protein for healthy, exercising individuals. Based on the current available literature, the position of the Society is as follows:An acute exercise stimulus, particularly resistance exercise, and protein ingestion both stimulate muscle protein synthesis (MPS) and are synergistic when protein consumption occurs before or after resistance exercise.For building muscle mass and for maintaining muscle mass through a positive muscle protein balance, an overall daily protein intake in the range of 1.4-2.0 g protein/kg body weight/day (g/kg/d) is sufficient for most exercising individuals, a value that falls in line within the Acceptable Macronutrient Distribution Range published by the Institute of Medicine for protein.Higher protein intakes (2.3-3.1 g/kg/d) may be needed to maximize the retention of lean body mass in resistance-trained subjects during hypocaloric periods.There is novel evidence that suggests higher protein intakes (>3.0 g/kg/d) may have positive effects on body composition in resistance-trained individuals (i.e., promote loss of fat mass).Recommendations regarding the optimal protein intake per serving for athletes to maximize MPS are mixed and are dependent upon age and recent resistance exercise stimuli. General recommendations are 0.25 g of a high-quality protein per kg of body weight, or an absolute dose of 20-40 g.Acute protein doses should strive to contain 700-3000 mg of leucine and/or a higher relative leucine content, in addition to a balanced array of the essential amino acids (EAAs).These protein doses should ideally be evenly distributed, every 3-4 h, across the day.The optimal time period during which to ingest protein is likely a matter of individual tolerance, since benefits are derived from pre- or post-workout ingestion; however, the anabolic effect of exercise is long-lasting (at least 24 h), but likely diminishes with increasing time post-exercise.While it is possible for physically active individuals to obtain their daily protein requirements through the consumption of whole foods, supplementation is a practical way of ensuring intake of adequate protein quality and quantity, while minimizing caloric intake, particularly for athletes who typically complete high volumes of training. Rapidly digested proteins that contain high proportions of essential amino acids (EAAs) and adequate leucine, are most effective in stimulating MPS. Different types and quality of protein can affect amino acid bioavailability following protein supplementation. Athletes should consider focusing on whole food sources of protein that contain all of the EAAs (i.e., it is the EAAs that are required to stimulate MPS). Endurance athletes should focus on achieving adequate carbohydrate intake to promote optimal performance; the addition of protein may help to offset muscle damage and promote recovery. Pre-sleep casein protein intake (30-40 g) provides increases in overnight MPS and metabolic rate without influencing lipolysis.
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Date Issued: 2017-06-20
Identifier: FSU_pmch_28642676, 10.1186/s12970-017-0177-8, PMC5477153, 28642676, 28642676, 177
Format: Citation

Title: Learning, Negotiating, and Surviving in Child Welfare: Social Capitalitalization Among Recently-hired Workers.
Creator: Radey, Melissa, Schelbe, Lisa, Spinelli, Carmella L.
Abstract/Description: In the child welfare workplace, accessible relationships and support, though understudied, are vital to worker success. Using telephone interviews with a statewide sample of recently-hired, frontline workers (N = 38), this study applied a social capital framework to consider support functionality or capitalization. Findings highlight that although nearly all workers recognized the importance of instrumental and expressive support, many workers did not capitalize on support. Agencies may...
Show moreIn the child welfare workplace, accessible relationships and support, though understudied, are vital to worker success. Using telephone interviews with a statewide sample of recently-hired, frontline workers (N = 38), this study applied a social capital framework to consider support functionality or capitalization. Findings highlight that although nearly all workers recognized the importance of instrumental and expressive support, many workers did not capitalize on support. Agencies may benefit from an atmosphere focused on collective interests rather than individual survival. Policy can promote supportive atmospheres through providing agencies with the ability and time to foster recently-hired workers’ skills.
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Date Issued: 2017-06-20
Identifier: FSU_libsubv1_scholarship_submission_1506004614_04e77df8, 10.1080/15548732.2017.1328380
Format: Citation

Title: Evaluating effectiveness of abstinence education.
Creator: Smith, Thomas E., Panisch, Lisa S., Malespin, Thallia, Pereira, Maria da Graca
Abstract/Description: Purpose: This study examined the effectiveness of an abstinence education program that was sensitive to federally mandated curriculum and measures. Methods: The intervention was delivered to 5,772 middle school and high school students. Effectiveness was assessed 10 by a measure that was anchored on A-H themes, which are components of federally mandated curricular components of abstinence education. To better understand the relationship of different variables and determine the significance of...
Show morePurpose: This study examined the effectiveness of an abstinence education program that was sensitive to federally mandated curriculum and measures. Methods: The intervention was delivered to 5,772 middle school and high school students. Effectiveness was assessed 10 by a measure that was anchored on A-H themes, which are components of federally mandated curricular components of abstinence education. To better understand the relationship of different variables and determine the significance of student’s improvements on the A-H measure scores, the ANCOVA was used with the pretest score 15 and age as covariates and the use of gender and ethnicity as fixed factors in the analysis. Results: While controlling for the effects of the pretest, the analyses showed that age and gender were main effects but that ethnicity did not prove to be related to the outcome scores. Results demonstrated that the effectiveness of the program 20 decreased as adolescent boys aged. There were no significant interactions in the gender and ethnicity variables. Conclusions: The findings of this study will be beneficial to program developers in understanding what variations and demographics are most receptive to this particular abstinence-only education model. Further studies in 25 this area are needed to evaluate the effectiveness of currently available programs.
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Date Issued: 2017-06-17
Identifier: FSU_libsubv1_scholarship_submission_1498264506_4d5bdf13, DOI:10.1080/23761407.2017.1340860
Format: Citation

Title: Upregulation Of Minichromosome Maintenance Complex Component 3 During Epithelial-to-mesenchymal Transition In Human Prostate Cancer.
Creator: Stewart, Paul A., Khamis, Zahraa I., Zhau, Haiyen E., Duan, Peng, Li, Quanlin, Chung, Leland W. K., Sang, Qing-Xiang Amy
Abstract/Description: Metastasis is often associated with epithelial-to-mesenchymal transition (EMT). To understand the molecular mechanisms of this process, we conducted proteomic analysis of androgen-repressed cancer of the prostate (ARCaP), an experimental model of metastatic human prostate cancer. The protein signatures of epithelial (ARCaP(E)) and mesenchymal (ARCaPM) cells were consistent with their phenotypes. Importantly, the expression of mini-chromosome maintenance 3 (MCM3) protein, a crucial subunit of...
Show moreMetastasis is often associated with epithelial-to-mesenchymal transition (EMT). To understand the molecular mechanisms of this process, we conducted proteomic analysis of androgen-repressed cancer of the prostate (ARCaP), an experimental model of metastatic human prostate cancer. The protein signatures of epithelial (ARCaP(E)) and mesenchymal (ARCaPM) cells were consistent with their phenotypes. Importantly, the expression of mini-chromosome maintenance 3 (MCM3) protein, a crucial subunit of DNA helicase, was significantly higher in ARCaP(M) cells than that of ARCaP(E) cells. This increased MCM3 protein expression level was verified using Western blot analysis of the ARCaP cell lineages. Furthermore, immunohistochemical analysis of MCM3 protein levels in human prostate tissue specimens showed elevated expression in bone metastasis and advanced human prostate cancer tissue samples. Subcutaneous injection experiments using ARCaP(E) and ARCaP(M) cells in a mouse model also revealed increased MCM3 protein levels in mesenchymal-derived tumors. This study identifies MCM3 as an upregulated molecule in mesenchymal phenotype of human prostate cancer cells and advanced human prostate cancer specimens, suggesting MCM3 may be a new potential drug target for prostate cancer treatment.
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Date Issued: 2017-06-13
Identifier: FSU_libsubv1_wos_000403311900096, 10.18632/oncotarget.16835
Format: Citation

Title: Lip Service or Actionable Insights?: Linking Student Experiences to Institutional Assessment and Data-Driven Decision Making in Higher Education.
Creator: Cox, Bradley E., Reason, Robert D., Tobolowsky, Barbara F., Brower, Rebecca L., Patterson, Shawna, Luczyk, Sarah, Roberts, Kari
Abstract/Description: Despite an increasing focus on issues of accountability, assessment, and data-driven decision making (DDDM) within the postsecondary context, assumptions regarding their value remain largely untested. The current study uses empirical data from 114 senior administrators and 8,847 students at 57 institutions in five states to examine the extent to which institutional assessment and data-driven decision making shape the experiences of first-year students. Nearly all these schools regularly...
Show moreDespite an increasing focus on issues of accountability, assessment, and data-driven decision making (DDDM) within the postsecondary context, assumptions regarding their value remain largely untested. The current study uses empirical data from 114 senior administrators and 8,847 students at 57 institutions in five states to examine the extent to which institutional assessment and data-driven decision making shape the experiences of first-year students. Nearly all these schools regularly collect some form of assessment data, and more than half report using assessment data to inform decision making. However, the institutional adoption of policies related to the collection of assessment data or the application of data-driven decision making appears to have no relationship with student experiences or outcomes in the first year of college. Thus, findings from the current study are consistent with the small, but growing, body of literature questioning the effectiveness of accountability and assessment policies in higher education. Roughly one in four students who begins college at a 4-year college or university does not return to that institution for a 2nd year (ACT Inc., 2016). This troubling statistic has not changed dramatically during the last 30 years, despite institutions of higher education implementing countless reforms in an effort to increase student success (e.g., learning, persistence, graduation). Among these efforts are hundreds of specific initiatives designed to facilitate student engagement, which has been found to predict student grades and persistence, particularly for underrepresented and underprepared students (Kuh, Cruce, Shoup, Kinzie, & Gonyea, 2008; Kuh, Kinzie, Buckley, Bridges, & Hayek, 2007)-with a strong focus on the critical 1st year of college (Barefoot et al., 2005; Upcraft & Gardner, 1989; Upcraft, Gardner, Barefoot, & Associates, 2005). Although various piecemeal initiatives have certainly contributed to improved outcomes at many institutions, they have not appreciably increased national persistence rates. As a result, educational policymakers and administrators have come under growing pressure to address this critical issue. However, this mandate is complicated by economic circumstances that have heightened the need for greater operational efficiency within higher education (Altbach, Berdahl, & Gumport, 2005; Paulsen & Smart, 2001). Responsive to these external pressures and in an effort to demonstrate their effectiveness, many colleges and universities are now spending hundreds of thousands of dollars, annually, to cover the costs of assessment (Cooper & Terrell, 2013), most of which continues to focus on student experiences and outcomes (Bresciani, Gardner, & Hickmott, 2009; Ory, 1992; Schuh, & Associates, 2009; Schuh & Gansemer-Topf, 2010). Underlying this approach is the assumption that educational quality is likely to be improved when decision makers develop policies and implement practices informed by relevant assessment data (i.e., “data-driven decision making” or DDDM). However, the assumption that assessment practices and DDDM by institutions of higher education yields improved student experiences and outcomes remains largely untested. Therefore, the purpose of this article was to articulate distinct perspectives on the use of assessment and DDDM in higher education, document the extent to which these practices have been implemented, and use empirical data from 114 senior administrators and 8,847 students at 57 diverse postsecondary institutions across five states to examine linkages between assessment/DDDM policies and student experiences in the 1st year of college. Specifically, this study addressed two research questions: 1. To what extent are institutions of higher education employing assessment and DDDM regarding students’ 1st year of college? 2. To what extent does institutional adoption of assessment and DDDM correspond to levels of 1st-year student engagement and perceived gains?
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Date Issued: 2017-06-07
Identifier: FSU_libsubv1_scholarship_submission_1496954725_bfae81e7, 10.1080/00221546.2016.1272320
Format: Citation

Title: Divergent Roles Of A Peripheral Transmembrane Segment In Ampa And Nmda Receptors.
Creator: Amin, Johansen B., Salussolia, Catherine L., Chan, Kelvin, Regan, Michael C., Dai, Jian, Zhou, Huan-Xiang, Furukawa, Hiro, Bowen, Mark E., Wollmuth, Lonnie P.
Abstract/Description: Ionotropic glutamate receptors (iGluRs), including AMPA receptor (AMPAR) and NMDA receptor (NMDAR) subtypes, are ligand-gated ion channels that mediate signaling at the majority of excitatory synapses in the nervous system. The iGluR pore domain is structurally and evolutionarily related to an inverted two-transmembrane K+ channel. Peripheral to the pore domain in eukaryotic iGluRs is an additional transmembrane helix, the M4 segment, which interacts with the pore domain of a neighboring...
Show moreIonotropic glutamate receptors (iGluRs), including AMPA receptor (AMPAR) and NMDA receptor (NMDAR) subtypes, are ligand-gated ion channels that mediate signaling at the majority of excitatory synapses in the nervous system. The iGluR pore domain is structurally and evolutionarily related to an inverted two-transmembrane K+ channel. Peripheral to the pore domain in eukaryotic iGluRs is an additional transmembrane helix, the M4 segment, which interacts with the pore domain of a neighboring subunit. In AMPARs, the integrity of the alignment of a specific face of M4 with the adjacent pore domain is essential for receptor oligomerization. In contrast to AMPARs, NMDARs are obligate heterotetramers composed of two GluN1 and typically two GluN2 subunits. Here, to address the function of the M4 segments in NMDARs, we carry out a tryptophan scan of M4 in GluN1 and GluN2A subunits. Unlike AMPARs, the M4 segments in NMDAR subunits makes only a limited contribution to their biogenesis. However, the M4 segments in both NMDAR subunits are critical for receptor activation, with mutations at some positions, most notably at the extreme extracellular end, completely halting the gating process. Furthermore, although the AMPAR M4 makes a minimal contribution to receptor desensitization, the NMDAR M4 segments have robust and subunit-specific effects on desensitization. These findings reveal that the functional roles of the M4 segments in AMPARs and NMDARs have diverged in the course of their evolution and that the M4 segments in NMDARs may act as a transduction pathway for receptor modulation at synapses.
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Date Issued: 2017-06
Identifier: FSU_libsubv1_wos_000404978000005, 10.1085/jgp.201711762
Format: Citation

Title: Adding Stable Carbon Isotopes Improves Model Representation Of The Role Of Microbial Communities In Peatland Methane Cycling.
Creator: Deng, Jia, McCalley, Carmody K., Frolking, Steve, Chanton, Jeff, Crill, Patrick, Varner, Ruth, Tyson, Gene, Rich, Virginia, Hines, Mark, Saleska, Scott R., Li, Changsheng
Abstract/Description: Climate change is expected to have significant and uncertain impacts on methane (CH4) emissions from northern peatlands. Biogeochemical models can extrapolate site-specificCH(4) measurements to larger scales and predict responses of CH4 emissions to environmental changes. However, these models include considerable uncertainties and limitations in representing CH4 production, consumption, and transport processes. To improve predictions of CH4 transformations, we incorporated acetate and stable...
Show moreClimate change is expected to have significant and uncertain impacts on methane (CH4) emissions from northern peatlands. Biogeochemical models can extrapolate site-specificCH(4) measurements to larger scales and predict responses of CH4 emissions to environmental changes. However, these models include considerable uncertainties and limitations in representing CH4 production, consumption, and transport processes. To improve predictions of CH4 transformations, we incorporated acetate and stable carbon (C) isotopic dynamics associated with CH4 cycling into a biogeochemistry model, DNDC. By including these new features, DNDC explicitly simulates acetate dynamics and the relative contribution of acetotrophic and hydro-genotrophic methanogenesis (AM and HM) to CH4 production, and predicts the C isotopic signature (delta C-13) in soil C pools and emitted gases. When tested against biogeochemical and microbial community observations at two sites in a zone of thawing permafrost in a subarctic peatland in Sweden, the new formulation substantially improved agreement with CH4 production pathways and delta C-13 in emitted CH4 (delta C-13-CH4), a measure of the integrated effects of microbial production and consumption, and of physical transport. We also investigated the sensitivity of simulated delta C-13-CH4 to C isotopic composition of substrates and, to fractionation factors for CH4 production (alpha(AM) and alpha(HM)), CH4 oxidation (alpha(MO)), and plant-mediated CH4 transport (alpha(TP)). The sensitivity analysis indicated that the delta C-13-CH4 is highly sensitive to the factors associated with microbial metabolism (alpha(AM), alpha(HM), and alpha(MO)). The model framework simulating stable C isotopic dynamics provides a robust basis for better constraining and testing microbial mechanisms in predicting CH4 cycling in peatlands.
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Date Issued: 2017-06
Identifier: FSU_libsubv1_wos_000406239300036, 10.1002/2016MS000817
Format: Citation

Title: The 2.8 Angstrom Electron Microscopy Structure Of Adeno-associated Virus-dj Bound By A Heparinoid Pentasaccharide.
Creator: Xie, Qing, Spear, John M., Noble, Alex J., Sousa, Duncan R., Meyer, Nancy L., Davulcu, Omar, Zhang, Fuming, Linhardt, Robert J., Stagg, Scott M., Chapman, Michael S.
Abstract/Description: Atomic structures of adeno-associated virus (AAV)-DJ, alone and in complex with fondaparinux, have been determined by cryoelectron microscopy at 3 angstrom resolution. The gene therapy vector, AAV-DJ, is a hybrid of natural serotypes that was previously derived by directed evolution, selecting for hepatocyte entry and resistance to neutralization by human serum. The structure of AAV-DJ differs from that of parental serotypes in two regions where neutralizing antibodies bind, so immune escape...
Show moreAtomic structures of adeno-associated virus (AAV)-DJ, alone and in complex with fondaparinux, have been determined by cryoelectron microscopy at 3 angstrom resolution. The gene therapy vector, AAV-DJ, is a hybrid of natural serotypes that was previously derived by directed evolution, selecting for hepatocyte entry and resistance to neutralization by human serum. The structure of AAV-DJ differs from that of parental serotypes in two regions where neutralizing antibodies bind, so immune escape appears to have been the primary driver of AAV-DJ's directed evolution. Fondaparinux is an analog of cell surface heparan sulfate to which several AAVs bind during entry. Fondaparinux interacts with viral arginines at a known heparin binding site, without the large conformational changes whose presence was controversial in low-resolution imaging of AAV2-heparin complexes. The glycan density suggests multimodal binding that could accommodate sequence variation and multivalent binding along a glycan polymer, consistent with a role in attachment, prior to more specific interactions with a receptor protein mediating entry.
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Date Issued: 2017-06
Identifier: FSU_libsubv1_wos_000406299600001, 10.1016/j.omtm.2017.02.004
Format: Citation

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