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Title: Multiple organ dysfunction and systemic inflammation after spinal cord injury.
Format: Citation

Title: Nanoparticle analysis sheds budding insights into genetic drivers of extracellular vesicle biogenesis.
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Title: Neurons That Underlie Drosophila melanogaster Reproductive Behaviors.
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Title: Bioinformatic analysis reveals the expression of unique transcriptomic signatures in Zika virus infected human neural stem cells.
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Title: PDF datastream.
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Title: Ubiquilin/Dsk2 promotes inclusion body formation and vacuole (lysosome)-mediated disposal of mutated huntingtin.
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Title: Rapid Identification and Characterization of Francisella by Molecular Biology and Other Techniques.
Format: Citation

Title: Sex Differences in Drosophila Somatic Gene Expression.
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Title: Spinal Microgliosis Due to Resident Microglial Proliferation Is Required for Pain Hypersensitivity after Peripheral Nerve Injury.
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Title: Sphingolipids in spinal cord injury.
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Title: Trichostatin A (TSA) facilitates formation of partner preference in male prairie voles (Microtus ochrogaster).
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Title: Discovery and evaluation of inhibitor of LARP6 as specific antifibrotic compound: antifibrotic drug.
Creator: Stefanovic, Branko, Manojlovic, Zarko, Vied, Cynthia, Badger, Crystal-Dawn, Stefanovic, Lela
Abstract/Description: Fibrosis is characterized by excessive production of type I collagen. Biosynthesis of type I collagen in fibrosis is augmented by binding of protein LARP6 to the 5’ stem-loop structure (5’SL), which is found exclusively in type I collagen mRNAs. A high throughput screen was performed to discover inhibitors of LARP6 binding to 5’SL, as potential antifibrotic drugs. The screen yielded one compound (C9) which was able to dissociate LARP6 from 5’ SL RNA in vitro and to inactivate the binding of...
Show moreFibrosis is characterized by excessive production of type I collagen. Biosynthesis of type I collagen in fibrosis is augmented by binding of protein LARP6 to the 5’ stem-loop structure (5’SL), which is found exclusively in type I collagen mRNAs. A high throughput screen was performed to discover inhibitors of LARP6 binding to 5’SL, as potential antifibrotic drugs. The screen yielded one compound (C9) which was able to dissociate LARP6 from 5’ SL RNA in vitro and to inactivate the binding of endogenous LARP6 in cells. Treatment of hepatic stellate cells (liver cells responsible for fibrosis) with nM concentrations of C9 reduced secretion of type I collagen. In precision cut liver slices, as an ex vivo model of hepatic fibrosis, C9 attenuated the profibrotic response at 1 μM. In prophylactic and therapeutic animal models of hepatic fibrosis C9 prevented development of fibrosis or hindered the progression of ongoing fibrosis when administered at 1 mg/kg. Toxicogenetics analysis revealed that only 42 liver genes changed expression after administration of C9 for 4 weeks, suggesting minimal off target effects. Based on these results, C9 represents the first LARP6 inhibitor with significant antifibrotic activity.
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Date Issued: 2019/01/23
Identifier: FSU_libsubv1_scholarship_submission_1550162176_d38b7a2e, 10.1038/s41598-018-36841-y
Format: Citation

Title: The Career State Inventory (CSI) as a Measure of Readiness for Career Decision Making: A Manual for Assessment, Administration, and Intervention 7.0* (Technical Report No. 57).
Creator: Leierer, Stephen J., Peterson, Gary W., Reardon, Robert C., Osborn, Debra S.
Abstract/Description: The Career State Inventory (CSI) was developed initially by the authors as the Career Decision State Survey (CDSS) to facilitate research and practice in vocational psychology and career development. This measure may also be used to assess readiness for career problem solving and decision making. The CSI was developed by the authors through the Center for the Study of Technology in Counseling and Career Development at Florida State University and it will be updated periodically. Others may...
Show moreThe Career State Inventory (CSI) was developed initially by the authors as the Career Decision State Survey (CDSS) to facilitate research and practice in vocational psychology and career development. This measure may also be used to assess readiness for career problem solving and decision making. The CSI was developed by the authors through the Center for the Study of Technology in Counseling and Career Development at Florida State University and it will be updated periodically. Others may freely use the instrument for research and practice with proper citation of the instrument and credit as noted below. Sale of the CSI for profit is not authorized by the authors or FSU. A link to the CSI and this Manual is provided at http://career.fsu.edu/Tech-Center. Manual topics include (a) an examination of the Career Decision State construct as a state of consciousness through the perspective of cognitive information processing theory (CIP); (b) prior research examining the concurrent validity of the CSI in relation to similar constructs; (c) procedures for administering and scoring the instrument; and (d) ways in which CSI results could be interpreted and implemented in the process of career service delivery or training of career services providers.
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Date Issued: 2017/04/18
Identifier: FSU_libsubv1_scholarship_submission_1517522495_ad48ff10, 10.17125/fsu.1517522495
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Title: Rescuing macrophage normal function in spinal cord injury with embryonic stem cell conditioned media.
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Title: Spindle assembly checkpoint silencing and beyond.
Format: Citation

Title: Mother Tongue: Gogol"s Pannochka, Pogorel'skii's Monastyrka, And The Economy Of Russian In The Little Russian Gothic.
Creator: Romanchuk, Robert
Date Issued: yyyy-MM-dd
Identifier: FSU_libsubv1_wos_000440264000004
Format: Citation

Title: 1-s2.0-S2352827318300272-main.
Format: Citation

Title: FSU_libsubv1_wos_000430521400007pdf.
Format: Citation

Title: Erasmus And France.
Creator: Leushuis, Reinier
Date Issued: yyyy-MM-dd
Identifier: FSU_libsubv1_wos_000444095500014, 10.1086/700444
Format: Citation

Title: Radiatively Generated Source Of Flavor Universal Scalar Soft Masses.
Creator: Chakraborty, Sabyasachi, Roy, Tuhin S.
Abstract/Description: We report that models of electroweak supersymmetry with gaugino mass unification and sequestered scalar masses can still produce viable spectra, as long as we include a set of nonstandard supersymmetry breaking terms, which are trilinear in scalars like the A-terms, but are nonholomorphic in visible sector fields unlike the A-terms. These terms impart a subtle feature to one loop renormalization group equations of soft supersymmetry breaking terms, indirectly sourcing flavor universal...
Show moreWe report that models of electroweak supersymmetry with gaugino mass unification and sequestered scalar masses can still produce viable spectra, as long as we include a set of nonstandard supersymmetry breaking terms, which are trilinear in scalars like the A-terms, but are nonholomorphic in visible sector fields unlike the A-terms. These terms impart a subtle feature to one loop renormalization group equations of soft supersymmetry breaking terms, indirectly sourcing flavor universal contributions to all scalar masses. These new contributions can even dominate over radiative corrections from bino, and help raise right handed sleptons above bino, while leaving a tell-tale signature in the spectrum.
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Date Issued: ue Aug 20 00:00:00 ED
Identifier: FSU_libsubv1_wos_000481820400007, 10.1103/PhysRevD.100.035020
Format: Citation

Title: Restorative Servicescapes In Health Care: Examining The Influence Of Hotel-like Attributes On Patient Well-being.
Creator: Mody, Makarand, Suess, Courtney, Dogru, Tarik
Abstract/Description: This study examines how 527 patients across different health states assessed the influence of hotel-like attributes on their well-being. Using theoretical mechanisms of attention restoration underlying restorative servicescapes, we postulated that hotel-like products and services will enhance patients' perceived well-being, which, in turn, will favorably affect their behavioral intentions. We also tested an alternative model that included additional direct relationships between hotel-like...
Show moreThis study examines how 527 patients across different health states assessed the influence of hotel-like attributes on their well-being. Using theoretical mechanisms of attention restoration underlying restorative servicescapes, we postulated that hotel-like products and services will enhance patients' perceived well-being, which, in turn, will favorably affect their behavioral intentions. We also tested an alternative model that included additional direct relationships between hotel-like products and services and behavioral intentions, based on the tenets of cue utilization theory. After conducting a series of nested model comparison procedures, we confirmed that the alternative model provided a theoretically and empirically stronger explanation for the dynamics of hotel-like restorative servicescapes. Although the differences between less healthy and more healthy patients were not statistically significant, the less healthy group demonstrated the same pattern of relationships as in the overall model, indicating that such patients may be more likely to derive greater restorative benefits from hotel-like hospital rooms, which may also make them more likely to pay higher out-of-pocket expenses for such rooms. The study furthers the empirical research agenda on evidence-based design (EBD) and the role of hospitality in health care.
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Identifier: FSU_libsubv1_wos_000489410500001, 10.1177/1938965519879430
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Title: Zn And P Alloying Effect In Sub-rapidly Solidified Lafe11.6si1.4 Magnetocaloric Plates.
Creator: Jin, Pingxia, Li, Yuqiang, Dai, Yuting, Xu, Zhishuai, Song, Changjiang, Luo, Zhiping, Zhai, Qijie, Han, Ke, Zheng, Hongxing
Abstract/Description: The occupation mechanism and magnetic transition behavior of trace Zn and P alloying in the sub-rapidly solidified LaFe11.6Si1.4 magnetocaloric plates were investigated. The LaFe11.6Si1.4, LaFe11.6Si1.4Zn0.03, and LaFe11.6Si1.4P0.03 plates were fabricated using the centrifugal casting method in the present work. Experimental results showed that both Zn and P elements were distributed in the La5Si3 and LaFeSi phases during sub-rapid solidification. After annealed at 1373 K for 72 h, the LaFe11...
Show moreThe occupation mechanism and magnetic transition behavior of trace Zn and P alloying in the sub-rapidly solidified LaFe11.6Si1.4 magnetocaloric plates were investigated. The LaFe11.6Si1.4, LaFe11.6Si1.4Zn0.03, and LaFe11.6Si1.4P0.03 plates were fabricated using the centrifugal casting method in the present work. Experimental results showed that both Zn and P elements were distributed in the La5Si3 and LaFeSi phases during sub-rapid solidification. After annealed at 1373 K for 72 h, the LaFe11.6Si1.4 plate underwent a second-order magnetic transition, while both the LaFe11.6Si1.4Zn0.03 and LaFe11.6Si1.4P0.03 plates underwent a first-order transition. In combination with X-ray diffraction results, it was proposed that both Zn and P atoms prefer to enter the 96i site substituting for FeII/Si atoms according to the density-functional reconstruction of crystallographic structure. The Zn addition led to a slight decrease in magnetic entropy change from 7.0 to 5.9 J/(kgK), while the P addition strikingly enhanced this property to 31.4 J/(kgK) under a magnetic field change of 3 T. The effective refrigeration capacity of the annealed LaFe11.6Si1.4P0.03 plate reached 189.9 J/kg.
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Date Issued: Mon Apr 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000467637000049, 10.3390/met9040432
Format: Citation

Title: Medical Library Impact on Active Learning in the College of Medicine Curriculum.
Creator: Epstein, Susan, Rosasco, Robyn, Heasley, Erica
Date Issued: 2018/06
Identifier: FSU_libsubv1_scholarship_submission_1544649405_e93487d3
Format: Citation

Title: Sexual Orientation, Partnership Status, And Work Patterns Among Us Young Adults.
Creator: Ueno, Koji, Grace, Jessi, Saras, Emily D.
Abstract/Description: Past research has shown that sexual minority women have a higher rate of labor force participation and work more hours than heterosexual women, and that men show the opposite sexual orientation differences. Little is known, however, about sexual orientation differences in work history. Further, many past studies, especially US studies, defined sexual orientation by the gender of residing partners and therefore excluded people who do not have a partner from analysis. This study sought to...
Show morePast research has shown that sexual minority women have a higher rate of labor force participation and work more hours than heterosexual women, and that men show the opposite sexual orientation differences. Little is known, however, about sexual orientation differences in work history. Further, many past studies, especially US studies, defined sexual orientation by the gender of residing partners and therefore excluded people who do not have a partner from analysis. This study sought to overcome these limitations by analyzing US data from the National Longitudinal Study of Adolescent to Adult Health, Wave 4 (n = 14,707). The analysis showed that compared to women in different-sex marriage, those in same-sex partnerships had a higher rate of labor force participation, worked more hours, and had a greater number of jobs in their work histories, although these women showed very small differences from those in different-sex cohabitation. In contrast, single women did not show any sexual orientation differences in these outcomes. Although partnered men and single men also showed very little sexual orientation differences, single men with same-sex experience had more jobs in their work histories than those with different-sex experience, partly due to their greater chance of experiencing involuntary job loss.
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Date Issued: hu Aug 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000477765200006, 10.1016/j.rssm.2019.100411
Format: Citation

Title: High-frequency And -field Epr (hfepr) Investigation Of A Pseudotetrahedral Cr-iv Siloxide Complex And Computational Studies Of Related (crl4)-l-iv Systems.
Creator: Bucinsky, Lukas, Breza, Martin, Malcek, Michal, Powers, David C., Hwang, Seung Jun, Krzystek, J., Nocera, Daniel G., Telser, Joshua
Abstract/Description: Chromium species are the active sites in a variety of heterogeneous catalysts, such as the Phillips catalyst, which is composed of Cr ions supported by SiO2 and is used to produce polyethylene. Among the catalytically relevant oxidation states of chromium is Cr-IV. Families of neutral, homoleptic, four -coordinate complexes, CrL4, with a variety of monoanionic, monodentate ligands, such as L = alkyls, aryls, amides, ketimides (R2C = N-) alkoxides, and siloxides, are available and can provide...
Show moreChromium species are the active sites in a variety of heterogeneous catalysts, such as the Phillips catalyst, which is composed of Cr ions supported by SiO2 and is used to produce polyethylene. Among the catalytically relevant oxidation states of chromium is Cr-IV. Families of neutral, homoleptic, four -coordinate complexes, CrL4, with a variety of monoanionic, monodentate ligands, such as L = alkyls, aryls, amides, ketimides (R2C = N-) alkoxides, and siloxides, are available and can provide information regarding Cr sites in heterogeneous materials. For example, the previously reported siloxide, Cr(DTBMS)(4), where DTBMS = -(OSiMeBu2)-Bu-t (di-tert-butylmethylsiloxide), may be considered a molecular analogue of Cr-IV supported by SiO2. Such CrL4 complexes can have either a singlet (S = 0) or triplet (S = 1) spin ground state, and the spin state preferences of such complexes are not fully understood. A truly tetrahedral d(2) S = 1 complex would exhibit no zero-field splitting (zfs), and the zfs is indeed small and observable by X-band EPR for several CrR4 and Cr(OR)(4) complexes. In contrast, Cr(DTBMS)(4) has zfs beyond the range amenable to X-band EPR so that high-frequency and high-field EPR (HFEPR) is appropriate. HFEPR of Cr(DTBMS)(4) in the solid state shows the presence of three very similar triplet species with the major component having D = +0.556 cm(-1). Classical ligand-field theory (LFT) and quantum chemical theory (QCT), including ab initio methods, use EPR and electronic absorption spectra to give a complete picture of the electronic structure of Cr(DTBMS)(4), and other complexes of formula Cr(ERn)(4), E = C, n = 3; E = N, n = 2; E = 0, n = E = F, n = 0. Computations show the importance of ligand steric bulk and of pi-bonding in controlling the subtleties of electronic structure of CrL4 species. These electronic structure results, including zfs, which is a measure of excited state accessibility, for both triplet and singlet excited states, might be related to the catalytic activity of paramagnetic Cr species.
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Date Issued: Mon Apr 15 00:00:00 ED
Identifier: FSU_libsubv1_wos_000465188700023, 10.1021/acs.inorgchem.8b03512
Format: Citation

Title: Bayesian Variable Selection For Pareto Regression Models With Latent Multivariate Log Gamma Process With Applications To Earthquake Magnitudes.
Creator: Yang, Hou-Cheng, Hu, Guanyu, Chen, Ming-Hui
Abstract/Description: Generalized linear models are routinely used in many environment statistics problems such as earthquake magnitudes prediction. Hu et al. proposed Pareto regression with spatial random effects for earthquake magnitudes. In this paper, we propose Bayesian spatial variable selection for Pareto regression based on Bradley et al. and Hu et al. to tackle variable selection issue in generalized linear regression models with spatial random effects. A Bayesian hierarchical latent multivariate log...
Show moreGeneralized linear models are routinely used in many environment statistics problems such as earthquake magnitudes prediction. Hu et al. proposed Pareto regression with spatial random effects for earthquake magnitudes. In this paper, we propose Bayesian spatial variable selection for Pareto regression based on Bradley et al. and Hu et al. to tackle variable selection issue in generalized linear regression models with spatial random effects. A Bayesian hierarchical latent multivariate log gamma model framework is applied to account for spatial random effects to capture spatial dependence. We use two Bayesian model assessment criteria for variable selection including Conditional Predictive Ordinate (CPO) and Deviance Information Criterion (DIC). Furthermore, we show that these two Bayesian criteria have analytic connections with conditional AIC under the linear mixed model setting. We examine empirical performance of the proposed method via a simulation study and further demonstrate the applicability of the proposed method in an analysis of the earthquake data obtained from the United States Geological Survey (USGS).
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Date Issued: Mon Apr 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000467305900024, 10.3390/geosciences9040169
Format: Citation

Title: Fractional Coalescent.
Creator: Mashayekhi, Somayeh, Beerli, Peter
Abstract/Description: An approach to the coalescent, the fractional coalescent (f-coalescent), is introduced. The derivation is based on the discretetime Cannings population model in which the variance of the number of offspring depends on the parameter alpha. This additional parameter alpha affects the variability of the patterns of the waiting times; values of alpha
Show moreAn approach to the coalescent, the fractional coalescent (f-coalescent), is introduced. The derivation is based on the discretetime Cannings population model in which the variance of the number of offspring depends on the parameter alpha. This additional parameter alpha affects the variability of the patterns of the waiting times; values of alpha < 1 lead to an increase of short time intervals, but occasionally allow for very long time intervals. When alpha = 1, the f-coalescent and the Kingman's n-coalescent are equivalent. The distribution of the time to the most recent common ancestor and the probability that n genes descend from m ancestral genes in a time interval of length T for the f-coalescent are derived. The f-coalescent has been implemented in the population genetic model inference software MIGRATE. Simulation studies suggest that it is possible to accurately estimate alpha values from data that were generated with known alpha values and that the f-coalescent can detect potential environmental heterogeneity within a population. Bayes factor comparisons of simulated data with alpha < 1 and real data (H1N1 influenza and malaria parasites) showed an improved model fit of the f-coalescent over the n-coalescent. The development of the f-coalescent and its inclusion into the inference program MIGRATE facilitates testing for deviations from the n-coalescent.
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Date Issued: ue Mar 26 00:00:00 ED
Identifier: FSU_libsubv1_wos_000462382800066, 10.1073/pnas.1810239116
Format: Citation

Title: Effects Of Interface Area Density And Solid Solution On The Microhardness Of Cu-nb Microcomposite Wires.
Creator: Deng, Liping, Liu, Zhifeng, Wang, Bingshu, Han, Ke, Xiang, Hongliang
Abstract/Description: Cu-Nb microcomposite wires drawn to different strain values were studied by means of scanning electron microscopy and transmission electron microscopy. The Cu and Nb near the interfaces show a typical Kurdjumov-Sachs relationship with a deviation angle of 12 degrees. This deviation accommodates internal stresses and slip discontinuity between Cu and Nb. The dislocations are mainly stored around the interface near the Cu matrix. Lattice distortion occurred near the interfaces, where Nb is...
Show moreCu-Nb microcomposite wires drawn to different strain values were studied by means of scanning electron microscopy and transmission electron microscopy. The Cu and Nb near the interfaces show a typical Kurdjumov-Sachs relationship with a deviation angle of 12 degrees. This deviation accommodates internal stresses and slip discontinuity between Cu and Nb. The dislocations are mainly stored around the interface near the Cu matrix. Lattice distortion occurred near the interfaces, where Nb is believed to mix into Cu matrix. Microhardness is affected by interface area density as well as by strain-induced lattice distortion, which can produce a supersaturated solid solution.
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Date Issued: Mon Apr 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000462420900008, 10.1016/j.matchar.2019.02.002
Format: Citation

Title: Higher-protein Intake And Physical Activity Are Associated With Healthier Body Composition And Cardiometabolic Health In Hispanic Adults.
Creator: Brown, Ann F., Prado, Carla M., Ghosh, Sunita, Leonard, Shawn M., Arciero, Paul J., Tucker, Katherine L., Ormsbee, Michael J.
Abstract/Description: Background: Higher protein (HP) intake and physical activity (PA) have been associated with improved lean soft tissue (LST) and reduced fat mass (FM). Puerto Ricans have among the highest age-adjusted prevalence (42.5%) of obesity, which may be associated with inadequate protein consumption and PA. We examined the relationship between protein intake and PA with body composition and biomarkers of cardiometabolic health in Puerto Rican adults. Methods: Participants included 959 Puerto Rican...
Show moreBackground: Higher protein (HP) intake and physical activity (PA) have been associated with improved lean soft tissue (LST) and reduced fat mass (FM). Puerto Ricans have among the highest age-adjusted prevalence (42.5%) of obesity, which may be associated with inadequate protein consumption and PA. We examined the relationship between protein intake and PA with body composition and biomarkers of cardiometabolic health in Puerto Rican adults. Methods: Participants included 959 Puerto Rican adults (71.4% women, 28.6% men) from the Boston Puerto Rican Health Study (BPRHS), aged 46-79 y (Women: age, 60.4 +/- 7.6 y, BMI, 32.9 +/- 6.8 kg/m(2); Men: age, 59.8 +/- 7.9 y, BMI, 30.1 +/- 5.2 kg/m(2)). Protein intake was assessed using a food frequency questionnaire and expressed as g/kg body weight/day in energy intake-adjusted equal cut point tertile categories (lower, moderate, higher: LP < 0.91 g/kg/d, MP >= 0.91 <= 1.11 g/kg/d, and HP > 1.11 g/kg/d). PA was assessed by questionnaire and expressed in tertile categories (low, moderate and high; PA1: <0.8 km/d, PA2: >= 0.8 <= 3.2 km/d, PA3: >3.2 km/d). Results: Participants with energy-adjusted HP had lower appendicular LST (ALST: 16.2 +/- 3.8 kg), LST (39.7 +/- 8.0 kg) and FM (25.6 +/- 8.1 kg) when compared to LP (ALST: 20.1 +/- 4.5 kg; LST: 49.5 +/- 10.0 kg; FM: 40.8 +/- 12.3 kg; P < 0.001) and MP (ALST: 18.2 +/- 4.3 kg; LST: 44.1 +/- 8.8 kg; FM: 32.2 +/- 9.8 kg; P < 0.001). However, when adjusted for total body weight (kg), relative LST was significantly greater in HP (58 +/- 9%) when compared to LP (53 +/- 9%; P < 0.001) and MP (56 +/- 9%; P < 0.001). Participants in PA3 had greater ALST (19.5 +/- 5.4 kg), and LST (58 +/- 10%), compared to PA1 (ALST: 17.2 +/- 4.3 kg; LST: 53 +/- 9%; P < 0.001) or PA2 (ALST: 17.7 +/- 4.7 kg; LST: 56 +/- 9%; P < 0.05). Those in HP + PA3 or MP + PA2 had lower c-reactive protein (CRP; HP + PA3: 5.1 +/- 6.8 mg/L; MP + PA2: 6.4 +/- 10.0 mg/L), when compared to LP + PA1 (8.7 +/- 8.8 mg/L; P < 0.05). Insulin concentration was lower for those in both the HP and PA3 (HP + PA3; 11.4 +/- 7.9 IU/mL) compared to those in both the LP and PA1 (LP + PAl; 20.7 +/- 16.3 Ul/mL) (P < 0.001). Conclusions: The highest tertiles of energy-adjusted protein intake (>= 1.11 g/kg/d) and PA (>3.2 km/d) were associated with more desirable indicators of overall body composition and cardiometabolic health, when adjusted for body weight, than those in the lower protein intake and PA in Puerto Rican adults. (C) 2019 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.
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Date Issued: Mon Apr 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000461813500021, 10.1016/j.clnesp.2019.01.002
Format: Citation

Title: Rapid Spatio-temporal Flood Prediction And Uncertainty Quantification Using A Deep Learning Method.
Creator: Hu, R., Fang, F., Pain, C. C., Navon, I. M.
Abstract/Description: Recently accrued attention has been given to machine learning approaches for flooding prediction. However, most of these studies focused mainly on time-series flooding prediction at specified sensors, rarely on spatio-temporal prediction of inundations. In this work, an integrated long short-term memory (LSTM) and reduced order model (ROM) framework has been developed. This integrated LSTM-ROM has the capability of representing the spatio-temporal distribution of floods since it takes...
Show moreRecently accrued attention has been given to machine learning approaches for flooding prediction. However, most of these studies focused mainly on time-series flooding prediction at specified sensors, rarely on spatio-temporal prediction of inundations. In this work, an integrated long short-term memory (LSTM) and reduced order model (ROM) framework has been developed. This integrated LSTM-ROM has the capability of representing the spatio-temporal distribution of floods since it takes advantage of both ROM and LSTM. To reduce the dimensional size of large spatial datasets in LSTM, the proper orthogonal decomposition (POD) and singular value decomposition (SVD) approaches are introduced. The LSTM training and prediction processes are carried out over the reduced space. This leads to an improvement of computational efficiency while maintaining the accuracy. The performance of the LSTM-ROM developed here has been evaluated using Okushiri tsunami as test cases. The results obtained from the LSTM-ROM have been compared with those from the full model (Fluidity). In predictive analytics, it is shown that the results from both the full model and LSTM-ROM are in a good agreement whilst the CPU cost using the LSTM-ROM is decreased by three orders of magnitude compared to full model simulations. Additionally, prescriptive analytics has been undertaken to estimate the uncertainty in flood induced conditions. Given the time series of the free surface height at a specified detector, the corresponding induced wave conditions along the coastline have then been provided using the LSTM network. Promising results indicate that the use of LSTM-ROM can provide the flood prediction in seconds, enabling us to provide real-time predictions and inform the public in a timely manner, reducing injuries and fatalities.
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Date Issued: hu Aug 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000488143000069, 10.1016/j.jhydrol.2019.05.087
Format: Citation

Title: A rabinosyl Deacetylase Modulates The Arabinoxylan Acetylation Profile And Secondary Wall Formation.
Creator: Zhang, Lanjun, Gao, Chengxu, Mentink-Vigier, Frederic, Tang, Lu, Zhang, Dongmei, Wang, Shaogan, Cao, Shaoxue, Xu, Zuopeng, Liu, Xiangling, Wang, Tuo, Zhou, Yihua, Zhang, Baocai
Abstract/Description: Acetylation, a prevalent modification of cell-wall polymers, is a tightly controlled regulatory process that orchestrates plant growth and environmental adaptation. However, due to limited characterization of the enzymes involved, it is unclear how plants establish and dynamically regulate the acetylation pattern in response to growth requirements. In this study, we identified a rice (Otyza sativa) GDSL esterase that deacetylates the side chain of the major rice hemicellulose, arabinoxylan....
Show moreAcetylation, a prevalent modification of cell-wall polymers, is a tightly controlled regulatory process that orchestrates plant growth and environmental adaptation. However, due to limited characterization of the enzymes involved, it is unclear how plants establish and dynamically regulate the acetylation pattern in response to growth requirements. In this study, we identified a rice (Otyza sativa) GDSL esterase that deacetylates the side chain of the major rice hemicellulose, arabinoxylan. Acetyl esterases involved in arabinoxylan modification were screened using enzymatic assays combined with mass spectrometry analysis. One candidate, DEACETYLASE ON ARABINOSYL SIDECHAIN OF XYLAN1 (DARX1), is specific for arabinosyl residues. Disruption of DARX1 via Tos17 insertion and CRISPR/Cas9 approaches resulted in the accumulation of acetates on the xylan arabinosyl side chains. Recombinant DARX1 abolished the excess acetyl groups on arabinoxylan-derived oligosaccharides of the darx1 mutants in vitro. Moreover, DARX1 is localized to the Golgi apparatus. Two-dimensional C-13-C-13 correlation spectroscopy and atomic force microscopy further revealed that the abnormal acetylation pattern observed in darx1 interrupts arabinoxylan conformation and cellulose microfibril orientation, resulting in compromised secondary wall patterning and reduced mechanical strength. This study provides insight into the mechanism controlling the acetylation pattern on arabinoxylan side chains and suggests a strategy to breed robust elite crops.
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Date Issued: Wed May 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000467755300014, 10.1105/tpc.18.00894
Format: Citation

Title: Consumption Of Benthic Cyanobacterial Mats On A Caribbean Coral Reef.
Creator: Cissell, Ethan C., Manning, Joshua C., McCoy, Sophie J.
Abstract/Description: Herbivory is an important process in the general structuring of coral reef benthic communities. However, evidence of its ability to control coral reef benthic cyanobacterial mats, which have recently proliferated on reefs worldwide, remains ambivalent. Here, we report that the French Angelfish (Pomacanthus paru), Striped Parrotfish (Scarus iseri), Rock Beauty (Holacanthus tricolor), Ocean Surgeonfish (Acanthurus bahianus), Blue Parrotfish (Scarus coeruleus), and Atlantic Blue Tang (Acanthurus...
Show moreHerbivory is an important process in the general structuring of coral reef benthic communities. However, evidence of its ability to control coral reef benthic cyanobacterial mats, which have recently proliferated on reefs worldwide, remains ambivalent. Here, we report that the French Angelfish (Pomacanthus paru), Striped Parrotfish (Scarus iseri), Rock Beauty (Holacanthus tricolor), Ocean Surgeonfish (Acanthurus bahianus), Blue Parrotfish (Scarus coeruleus), and Atlantic Blue Tang (Acanthurus coeruleus) consume benthic cyanobacterial mats on coral reefs in Bonaire, Netherlands. We documented the foraging patterns of P. paru and S. iseri, and found that benthic cyanobacterial mats comprised 36.7%+/- 5.8% and 15.0% +/- 1.53% (mean +/- standard error) of the total bites taken by P. paru and S. iseri respectively. This magnitude of consumption suggests that grazing by reef fishes may represent a potentially important, but previously undocumented, top-down control on benthic cyanobacterial mats on Caribbean reefs.
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Date Issued: ue Sep 03 00:00:00 ED
Identifier: FSU_libsubv1_wos_000483700400026, 10.1038/s41598-019-49126-9
Format: Citation

Title: Testing Restorative Narratives In A College Student Resilience Project.
Creator: Ray, Elizabeth C., Arpan, Laura, Oehme, Karen, Perko, Ann, Clark, James
Abstract/Description: A new online program, The Student Resilience Project (https://strong.fsu.edu), explores how institutions can effectively communicate health and resilience information to students. We investigated one key element of a pilot version of this program, specifically its use of video-based "restorative narratives," which depict college students overcoming adversity using institutional resources. We proposed a theoretical model, which is supported by data from a survey completed by undergraduate...
Show moreA new online program, The Student Resilience Project (https://strong.fsu.edu), explores how institutions can effectively communicate health and resilience information to students. We investigated one key element of a pilot version of this program, specifically its use of video-based "restorative narratives," which depict college students overcoming adversity using institutional resources. We proposed a theoretical model, which is supported by data from a survey completed by undergraduate students (n = 229) who viewed the videos. Results suggest that perceptions of restorative narratives can directly predict students' behavioral intentions, including their intention to seek resources and to share content with other students. Perceptions of restorative narratives also influenced behavioral intentions indirectly via their influence on meaningful affect and outcome expectations, including the belief that advice and resources would help them and others. Based on the model, we offer evidence-based suggestions for web-based prevention programs.
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Date Issued: hu Aug 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000476538400003, 10.1007/s10755-019-9464-4
Format: Citation

Title: Columns In Context: Venerable Monuments And Landscapes Of Memory In Early India.
Creator: Cecil, Elizabeth A., Bisschop, Peter C.
Date Issued: Wed May 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000466132000001
Format: Citation

Title: Employment Among Unaccompanied Women Experiencing Homelessness.
Creator: Groton, Danielle B., Radey, Melissa
Abstract/Description: Women represent one of the fastest growing segments of the homeless population and employment is often central exiting homelessness. However, little research considers employment experiences among unaccompanied women, a particularly vulnerable sub-population. This study explored how unaccompanied women experiencing homelessness (n = 20) perceived and negotiated employment in a mid-sized community. Thematic analysis revealed four themes: limited work experience, limited aspirations, the...
Show moreWomen represent one of the fastest growing segments of the homeless population and employment is often central exiting homelessness. However, little research considers employment experiences among unaccompanied women, a particularly vulnerable sub-population. This study explored how unaccompanied women experiencing homelessness (n = 20) perceived and negotiated employment in a mid-sized community. Thematic analysis revealed four themes: limited work experience, limited aspirations, the holding pattern, and individual barriers. Findings endorse the need for Housing-First interventions to prioritize stable housing and employment-friendly shelters.
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Date Issued: Wed Jul 03 00:00:00 ED
Identifier: FSU_libsubv1_wos_000465826600001, 10.1080/10530789.2019.1598606
Format: Citation

Title: The Balance Of Trade And Exchange Rates: Theory And Contemporary Evidence From Tourism.
Creator: Dogru, Tarik, Isik, Cem, Sirakaya-Turk, Ercan
Abstract/Description: The purpose of this study is to investigate the effects of exchange rate depreciations and appreciations on the tourism trade balance. Specifically, we employed linear and nonlinear autoregressive distributed lag (ARDL) cointegration techniques to analyze the extent to which currency depreciations and appreciations affect the United States (U.S.) bilateral tourism trade with Canada, Mexico, and the United Kingdom (U.K.). The results showed that the depreciation of the U.S. dollar subsequently...
Show moreThe purpose of this study is to investigate the effects of exchange rate depreciations and appreciations on the tourism trade balance. Specifically, we employed linear and nonlinear autoregressive distributed lag (ARDL) cointegration techniques to analyze the extent to which currency depreciations and appreciations affect the United States (U.S.) bilateral tourism trade with Canada, Mexico, and the United Kingdom (U.K.). The results showed that the depreciation of the U.S. dollar subsequently improves the U.S. trade balance with all three trading partners. However, while the appreciation of the U.S. dollar deteriorates the U.S. bilateral tourism trade balance with Canada and the U.K., it does not ultimately affect the U.S. bilateral tourism trade with Mexico in the long term. These results provide evidence contradicting the J-curve theory, supporting the postulations of the ML condition. Theoretical and policy implications are discussed within the realms of J-curve theory, Marshall-Lerner (ML) condition, international trade, and tourism.
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Date Issued: ue Oct 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000469890300002, 10.1016/j.tourman.2019.01.014
Format: Citation

Title: Higher-protein Intake And Physical Activity Are Associated With Healthier Body Composition And Cardiometabolic Health In Hispanic Adults.
Format: Citation

Title: Investigating The Effects Of Bulky Allylic Substituents On The Regioregularity And Thermodynamics Of Romp On Cyclopentene.
Creator: Guillory, Gina A., Kennemur, Justin G.
Abstract/Description: The interplay between equilibrium ROMP thermodynamics and the regioregular insertion of allylic trialkylsiloxy-substituted cyclopentenes during propagation with Hoveyda-Grubbs 2nd generation catalyst at varying temperatures is investigated. In general, bulkier substituents reduce monomer conversion and increase regioregular insertion. However, polymerization entropy (Delta S-P) also appears to play an important role on ROMP thermodynamics when compared to ring strain (Delta H-P) which is...
Show moreThe interplay between equilibrium ROMP thermodynamics and the regioregular insertion of allylic trialkylsiloxy-substituted cyclopentenes during propagation with Hoveyda-Grubbs 2nd generation catalyst at varying temperatures is investigated. In general, bulkier substituents reduce monomer conversion and increase regioregular insertion. However, polymerization entropy (Delta S-P) also appears to play an important role on ROMP thermodynamics when compared to ring strain (Delta H-P) which is typically the parameter of focus for the efficacy of low-strain monomer conversion. This analysis has allowed for the determination of a "Goldilocks" monomer (i.e. one that provides the best compromise of monomer conversion (56% conversion at - 10 degrees C) and regioregularity (97% HT insertion) to be 3-(tert-butyldimethylsiloxy)cyclopentene which has never before been explored or reported. Due to this study, this monomer has now been identified as the ideal choice for isotactic polypentenamer studies moving forward.
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Date Issued: Fri Nov 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000498309000080, 10.1016/j.eurpolymj.2019.109251
Format: Citation

Title: Tracing Underground Sources Of Pollution To Coastal Waters Off Map Ta Phut, Rayong, Thailand.
Creator: Burnett, William C., Sola, Phachirarat, Chanyotha, Supitcha, Bidorn, Butsawan, Kritsananuwat, Rawiwan, Chinfak, Narainrit
Abstract/Description: We explored the possibility that an underground pathway, "submarine groundwater discharge" (SGD), may contribute to the observed coastal contamination from a large industrial complex on the Gulf of Thailand. Three surveys were performed to map the area for the natural groundwater tracers radon, thoron and salinity. The results from all three surveys were internally consistent showing a point source adjacent to a large pier that serves the complex. It may be that a piling, driven into the...
Show moreWe explored the possibility that an underground pathway, "submarine groundwater discharge" (SGD), may contribute to the observed coastal contamination from a large industrial complex on the Gulf of Thailand. Three surveys were performed to map the area for the natural groundwater tracers radon, thoron and salinity. The results from all three surveys were internally consistent showing a point source adjacent to a large pier that serves the complex. It may be that a piling, driven into the ground to support the pier, intercepted a shallow aquifer and this resulted in an underground pathway between land and sea. Some low-density sediments are enriched in radium, we suspect from fly ash from a nearby power plant. Water quality parameters showed that total petroleum hydrocarbons (TPHs) correlated strongly to nitrite, dissolved inorganic phosphate and silica, indicating a common source. Data analysis shows that diffuse seepage accounts for more discharge than the point source.
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Date Issued: Fri Nov 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000498277600009, 10.1016/j.marpolbul.2019.07.071
Format: Citation

Title: Trends In Mood And Anxiety Symptoms And Suicide-related Outcomes Among.
Creator: Duffy, Mary E., Twenge, Jean M., Joiner, Thomas E.
Abstract/Description: Purpose: Past work has evidenced increased utilization of mental health services on college campuses, as well as rising rates of mood and suicide-related pathology in adolescents and young adults in recent years. We examined whether such findings are reflective of large-scale, nationwide trends in college student mental health in the past decade. Methods: We examined trends in mood, anxiety, and suicide-related outcomes among U.S. college students from 2007 to 2018 across two large national...
Show morePurpose: Past work has evidenced increased utilization of mental health services on college campuses, as well as rising rates of mood and suicide-related pathology in adolescents and young adults in recent years. We examined whether such findings are reflective of large-scale, nationwide trends in college student mental health in the past decade. Methods: We examined trends in mood, anxiety, and suicide-related outcomes among U.S. college students from 2007 to 2018 across two large national datasets: (1) the National College Health Assessment (n = 610,543; mean age = 21.25 years; 67.7% female; and 72.0% white) and (2) the Healthy Minds Study (n = 177,692; 86% students aged 18-22 years; 57% female; and 74% white). Participants, randomly selected by their educational institution, completed self-report measures of past-year mood, anxiety, nonsuicidal self-injury, and suicidal thoughts and behaviors. Results: In both samples, rates of depression, anxiety, nonsuicidal self-injury, suicidal ideation, and suicide attempts markedly increased over the assessed years, with rates doubling over the period in many cases. Anger, low flourishing, and suicide plans, each assessed in only one dataset, also exhibited upward trends. Conclusions: Findings demonstrate a broad worsening of mental health among U.S. college students over the past decade, a concerning result meriting further attention and intervention. (C) 2019 Society for Adolescent Health and Medicine. All rights reserved.
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Date Issued: Fri Nov 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000491239600007, 10.1016/j.jadohealth.2019.04.033
Format: Citation

Title: Understanding The Relationship Between Commitment Anxiety And Career Tension.
Creator: Finklea, J. Tyler, Osborn, Debra S.
Abstract/Description: Many college students experience a degree of anxiety and indecision related to choosing a major or career path. This study examined the relationship between commitment anxiety, as defined by cognitive information processing theory, and career tension in 101 undergraduate college students enrolled in a career planning class. Results of Pearson product-moment correlations showed a significant positive relationship and medium effect size between a student's commitment anxiety and career tension...
Show moreMany college students experience a degree of anxiety and indecision related to choosing a major or career path. This study examined the relationship between commitment anxiety, as defined by cognitive information processing theory, and career tension in 101 undergraduate college students enrolled in a career planning class. Results of Pearson product-moment correlations showed a significant positive relationship and medium effect size between a student's commitment anxiety and career tension levels. The results suggest that commitment anxiety and career tension are distinct but related constructs and that career counselors can help clients by reducing and managing these emotional concerns that often accompany career concerns.
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Date Issued: Sun Sep 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000484937800002, 10.1002/joec.12126
Format: Citation

Title: Exploring Twitter Use And Services Of Academic Innovation Centers.
Creator: Stvilia, Besiki, Gibradze, Leila
Abstract/Description: This study examined the Twitter streams and websites of 36 university innovation centers and identified 14 service categories the centers offered. Exploring the present Twitter use practices of innovation centers and the services the centers provide can inform the design and planning of service offerings at new innovation centers and support training for center staff in the use of this social media platform. In addition, existing innovation centers can benchmark their service offerings...
Show moreThis study examined the Twitter streams and websites of 36 university innovation centers and identified 14 service categories the centers offered. Exploring the present Twitter use practices of innovation centers and the services the centers provide can inform the design and planning of service offerings at new innovation centers and support training for center staff in the use of this social media platform. In addition, existing innovation centers can benchmark their service offerings against those services. Furthermore, mapping the services the innovation centers offer to the activities in an innovation workflow model can help center managers optimize the information architecture of their websites and resource guides. In this way, students can easily be informed about the help and resources available for each activity or phase of the innovation process. A comparison of the tweet categories identified in the present study with those of academic libraries assembled in a previous study revealed significant overlap, but some differences as well. In contrast to the Twitter accounts of academic libraries, the Twitter accounts of innovation centers did not tweet about their information services even if they offered them. Innovation centers also did not use Twitter to provide Q&A services to their users. Furthermore, innovation centers tweeted not only about the technological resources they provided, but also about the human resources they recruited to serve as student mentors and advisors. Finally, technology use was more mediated in innovation centers than in libraries, and some centers offered their users fee-based assistance from professionals with their 3D design and printing tasks.
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Date Issued: Sun Sep 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000487769400010, 10.1016/j.acalib.2019.102052
Format: Citation

Title: Fast Science, Slow Science: Finding Balance in the Time of COVID-19 and the Age of Misinformation.
Creator: Dunleavy, Daniel J., Hendricks, Vincent F.
Abstract/Description: The COVID-19 pandemic has placed politicians, community leaders, and everyday citizens in a difficult position. Decisions need to be made, but are typically done so with incomplete information, and often with a sense of anxiety and urgency. We discuss how the pandemic has changed science, for better and for worse, how this change affects decision-making, and how it interrelates with broader social phenomenon, such as the hyperconnectivity of the information age and consequent spread of...
Show moreThe COVID-19 pandemic has placed politicians, community leaders, and everyday citizens in a difficult position. Decisions need to be made, but are typically done so with incomplete information, and often with a sense of anxiety and urgency. We discuss how the pandemic has changed science, for better and for worse, how this change affects decision-making, and how it interrelates with broader social phenomenon, such as the hyperconnectivity of the information age and consequent spread of misinformation. Taken together, these issues place us at high risk for implementing poor policies and making dangerous decisions about personal safety. We end by considering some ways that science can be made more rigorous, in order to inform policies related to the pandemic and other social problems, how scientists may play a more active role in policy-decisions, and how citizens and community leaders can make better informed decisions themselves.
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Date Issued: 2020/09/28
Identifier: FSU_libsubv1_scholarship_submission_1601320901_aa2b6ce7, 10.5281/zenodo.4056908
Format: Citation

Title: Creative Destruction: Getting Ahead And Staying Ahead In A Capitalist Economy.
Creator: Holcombe, Randall G.
Abstract/Description: The creative destruction inherent in a capitalist economy enables entrepreneurial individuals to get ahead, but threatens those who want to stay ahead. Those who want to get ahead benefit from the continual evolution that characterizes a market economy, whereas those who want to stay ahead prefer stability and want to establish institutions that preserve the status quo. Those who want to stay ahead push for government regulations, subsidies, differential tax benefits, and other politically...
Show moreThe creative destruction inherent in a capitalist economy enables entrepreneurial individuals to get ahead, but threatens those who want to stay ahead. Those who want to get ahead benefit from the continual evolution that characterizes a market economy, whereas those who want to stay ahead prefer stability and want to establish institutions that preserve the status quo. Those who want to stay ahead push for government regulations, subsidies, differential tax benefits, and other politically generated protections that preserve the status quo and inhibit creative destruction. Long-established firms have an advantage in doing so because they tend to have more financial resources to devote to rent-seeking, and often have long-standing political connections. To prevent capitalist institutions from being undermined by those who want to stay ahead requires a robust entrepreneurial class that can give those who want to get ahead sufficient political influence to counter those who want to stay ahead.
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Identifier: FSU_libsubv1_wos_000552959800001, 10.1007/s11138-020-00523-8
Format: Citation

Title: Equality Of Authority As The Aristotelian Common Good.
Creator: LeBar, Mark
Identifier: FSU_libsubv1_wos_000553759300002, 10.1007/s10790-020-09758-x
Format: Citation

Title: Clinical Trials And The Origins Of Pharmaceutical Fraud: Parke, Davis & Company, Virtue Epistemology, And The History Of The Fundamental Antagonism.
Creator: Gabriel, Joseph M., Holman, Bennett
Abstract/Description: This paper describes one possible origin point for fraudulent behavior within the American pharmaceutical industry. We argue that during the late nineteenth century therapeutic reformers sought to promote both laboratory science and increasingly systematized forms of clinical experiment as a new basis for therapeutic knowledge. This process was intertwined with a transformation in the ethical framework in which medical science took place, one in which monopoly status was replaced by clinical...
Show moreThis paper describes one possible origin point for fraudulent behavior within the American pharmaceutical industry. We argue that during the late nineteenth century therapeutic reformers sought to promote both laboratory science and increasingly systematized forms of clinical experiment as a new basis for therapeutic knowledge. This process was intertwined with a transformation in the ethical framework in which medical science took place, one in which monopoly status was replaced by clinical utility as the primary arbiter of pharmaceutical legitimacy. This new framework fundamentally altered the set of epistemic virtues-a phrase we draw from the philosophical field of virtue epistemology-considered necessary to conduct reliable scientific inquiry regarding drugs. In doing so, it also made possible new forms of fraud in which newly emergent epistemic virtues were violated. To make this argument, we focus on the efforts of Francis E. Stewart and George S. Davis of Parke, Davis & Company. Therapeutic reformers within the pharmaceutical industry, such as Stewart and Davis, were an important part of the broader normative and epistemic transformation we describe in that they sought to promote laboratory science and systematized clinical trials toward the twin goals of improving pharmaceutical science and promoting their own commercial interests. Yet, as we suggest, Parke, Davis & Company also serves as an example of a company that violated the very norms that Stewart and Davis helped introduce. We thus seek to describe one possible origin point for the widespread fraudulent practices that now characterize the pharmaceutical industry. We also seek to describe an origin point for why we conceptualize such practices as fraudulent in the first place.
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Identifier: FSU_libsubv1_wos_000552727100001, 10.1177/0073275320942435
Format: Citation

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