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Why Young Adult Fiction: From 1960s to Today
Title
Why Young Adult Fiction: From 1960s to Today.
Creator
Cleveland, Eleanor
Date Issued
2018-04-24
Identifier
FSU_libsubv1_scholarship_submission_1524586367_450b0f79
Format
Thesis
wide paper on narrow content
Title
A wide paper on narrow content.
Creator
James, Matt
Date Issued
2002
Identifier
159840, FSDT159840, fsu:18624
Format
Document (PDF)
Wiki-Donna
Title
Wiki-Donna: A Contribution to a More Gender-Balanced History of Italian Literature Online.
Creator
D'Alessandro, Zoe
Date Issued
2020-04-21
Identifier
FSU_libsubv1_scholarship_submission_1587489218_f26e5731
Format
Thesis
Wild type and DDK phosphorylated MCM2 demonstrate unique binding specificities for RLF2 and CAC2 respectively.
Title
Wild type and DDK phosphorylated MCM2 demonstrate unique binding specificities for RLF2 and CAC2 respectively.
Creator
Jones, John Matthew
Abstract/Description
Minichromosome maintenance complex 2-7 (MCM2-7) is a fundamental component of the replicative CMG helicase (CDC45-MCM-GINS) characteristic of active eukaryotic replication forks. MCM2-7 is composed of 6 subunits, some of which are capable of receiving Dbf4-Cdc7 kinase (DDK) phosphorylation. Specifically, one of the six MCM2-7 subunits, MCM2, is associated with CMG complex activation upon MCM2 phosphorylation from DDK. Dr. Daniel Kaplan of Florida State University has developed an MCM2...
Show moreMinichromosome maintenance complex 2-7 (MCM2-7) is a fundamental component of the replicative CMG helicase (CDC45-MCM-GINS) characteristic of active eukaryotic replication forks. MCM2-7 is composed of 6 subunits, some of which are capable of receiving Dbf4-Cdc7 kinase (DDK) phosphorylation. Specifically, one of the six MCM2-7 subunits, MCM2, is associated with CMG complex activation upon MCM2 phosphorylation from DDK. Dr. Daniel Kaplan of Florida State University has developed an MCM2 phosphomutant (MCM2 11e) shown to mimic DDK phosphorylated MCM2, and therefore MCM2 that is present in active CMG helicase complexes [19]. Recent research of MCM2 has suggested accessory activities of the MCM2 protein aside from participation in the MCM2-7 ring of the CMG helicase complex. One particular function is histone chaperoning of H3-H4 dimers, a characteristic shared by chromatin assembly factor 1 (CAF-1). CAF-1 is known to deposit H3-H4 dimers at the replication fork, providing enough suspicion to investigate MCM2-CAF-1 interactions. In this Honors Thesis, GST pull-down assays were conducted to test MCM2 wild type (wt) and 11e binding efficiencies for 2 of 3 CAF-1 subunits, RLF2 and CAC2. Results indicate significant MCM2 wt affinity for RLF2, affinity not reciprocated by MCM2 11e. However, neither MCM2 wt nor 11e exhibit binding efficiencies greater than solely GST tag controls do for CAC2. The preferential binding of MCM2 wt to RLF2 and the shared repulsion of CAC2 by MCM2 wt and 11e identify MCM2 binding specificity to CAF-1 subunits not previously identified.
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Date Issued
2016-12-09
Identifier
FSU_libsubv1_scholarship_submission_1481561146
Format
Thesis
Wilde women: gender and performance in the social comedies of Oscar Wilde
Title
Wilde women: gender and performance in the social comedies of Oscar Wilde.
Creator
Velasco, Schuyler., Florida State University
Abstract/Description
This project discusses performance and gender issues in the social comedies of Oscar Wilde. Despite his strong identification as an aesthete, privileging art for its own sake separate from the natural realm, Wilde's social comedies deal with very real challenges of women during a transitional period in the history of European feminism, just before suffrage in England became an issue and the role of women began to shift to the public sphere. Wilde's comedies often been analyzed solely on the...
Show moreThis project discusses performance and gender issues in the social comedies of Oscar Wilde. Despite his strong identification as an aesthete, privileging art for its own sake separate from the natural realm, Wilde's social comedies deal with very real challenges of women during a transitional period in the history of European feminism, just before suffrage in England became an issue and the role of women began to shift to the public sphere. Wilde's comedies often been analyzed solely on the basis of text, rather than as pieces of art meant to be both viewed and read. My argument is that a full understanding of Wilde's plays requires both textual and performative analyses, and that Wilde's female characters, rather than the oft-studied male figures, are the characters that best exemplify the necessity of this dualistic study. In addition to looking at Wilde through the lens of performance theorists such as Judith Butler and Eve Sedgwick, this project analyzes adaptations of The Importance of Being Earnest and Lady Windermere's Fan from the silent film era to the present.
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Date Issued
2008
Identifier
471832288, 341819, FSDT341819, fsu:19388
Format
Document (PDF)
Wildfire Modeling
Title
Wildfire Modeling: Developing a computer simulation of a burning front using the reaction-diffusion equation.
Creator
Yarboro, Jennifer
Date Issued
2017-04-25
Identifier
FSU_libsubv1_scholarship_submission_1493400754
Format
Thesis
Will and Ethics of Belief
Title
The Will and Ethics of Belief: Epistemic Risks and Moral Consequences.
Creator
Duddles, Nathan, Philosophy
Abstract/Description
Debate over the ethics of belief has centered around two famous essays: W. K. Clifford's "The Ethics of Belief," and William James' "The Will to Believe." The former argues that it is never morally right to believe or accept a proposition beyond its evidential support; the latter defends the moral permissibility of a specific class of beliefs, including religious faith-commitments. I present interpretations of both essays, critiques of some contemporary arguments they have inspired and my own...
Show moreDebate over the ethics of belief has centered around two famous essays: W. K. Clifford's "The Ethics of Belief," and William James' "The Will to Believe." The former argues that it is never morally right to believe or accept a proposition beyond its evidential support; the latter defends the moral permissibility of a specific class of beliefs, including religious faith-commitments. I present interpretations of both essays, critiques of some contemporary arguments they have inspired and my own account of how to morally evaluate forming belief and acting on propositions. My thesis is that we must take seriously the moral consequences of belief when evaluating and choosing between alternative belief-forming practices and deciding to accept and act upon a proposition.
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Date Issued
2012
Identifier
FSU_migr_uhm-0086
Format
Thesis
Will Financial Literacy Impact Students' Financial Decisions?
Title
Will Financial Literacy Impact Students' Financial Decisions?.
Creator
Green, Shelby, Department of Political Science
Abstract/Description
This article addresses the impact of financial literacy on high school students' financial decisions. To analyze the impact, financial literacy information was provided to the treatment group and the treatment and control group discussed college expectations. Following the treatment or non-treatment, students completed a survey that was used to measure their financial decisions. Here we find that there was no significant impact. I discuss ways in which other variables impacted our outcome and...
Show moreThis article addresses the impact of financial literacy on high school students' financial decisions. To analyze the impact, financial literacy information was provided to the treatment group and the treatment and control group discussed college expectations. Following the treatment or non-treatment, students completed a survey that was used to measure their financial decisions. Here we find that there was no significant impact. I discuss ways in which other variables impacted our outcome and I propose alternatives for future research.
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Date Issued
2013
Identifier
FSU_migr_uhm-0161
Format
Thesis
Will releaseing solanum carolinense from herbiviores in its native range cause it to have invasive qualities?
Title
Will releaseing solanum carolinense from herbiviores in its native range cause it to have invasive qualities?.
Creator
Bielfelt, Brian J.
Date Issued
2005-06-21
Identifier
160537, FSDT160537, fsu:18958
Format
Document (PDF)
William Robinson: the architect of the international horn workshops
Title
William Robinson: the architect of the international horn workshops.
Creator
Bonaparte, Sabrina
Date Issued
2003
Identifier
160057, FSDT160057, fsu:18732
Format
Document (PDF)
Willingness to participate in job-related training as one approaches retirement
Title
Willingness to participate in job-related training as one approaches retirement.
Creator
Rojas, Frank Alexander., Florida State University
Abstract/Description
Abstract: Workers are increasingly becoming older and due to economic and societal conditions retirement is being discouraged (Ford & Orel, 2005). These individuals will continue to work for their employer and to be viable they may be willing to take on job-related training. An important factor that can influence an individual to accept training is motivation. One aspect of motivation is the Socio-emotional Selectivity Theory framework that Carstensen, Isaacowitz, and Charles (1999) proposed....
Show moreAbstract: Workers are increasingly becoming older and due to economic and societal conditions retirement is being discouraged (Ford & Orel, 2005). These individuals will continue to work for their employer and to be viable they may be willing to take on job-related training. An important factor that can influence an individual to accept training is motivation. One aspect of motivation is the Socio-emotional Selectivity Theory framework that Carstensen, Isaacowitz, and Charles (1999) proposed. It sees time as fundamental to motivation, suggesting that people with shorter time frames will seek emotional gratifications and those with longer frames will prefer information seeking gratification to further their careers. I tested predictions from this framework. Individuals with shorter time frames until retirement should be less willing to participate in job-related training than those with longer time frames. After running regressions using data from Workforce Ageing in the New Economy (WANE) data set and taking into account additional factors such as the correlation of age with time until retirement and excluding those with extreme amounts of training, there was little support for this assumption. However, there is a trend in the right direction. Further studies need to be done to investigate types of training given, reasons for retirement at chosen time, personality, within different industries and firm sizes.
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Date Issued
2009
Identifier
456453548, 244598, FSDT244598, fsu:19305
Format
Document (PDF)
Willingness to Participate in Job-Related Training as One Approaches Retirement
Title
Willingness to Participate in Job-Related Training as One Approaches Retirement.
Creator
Rojas, Frank, Department of Psychology
Abstract/Description
Workers are increasingly becoming older and due to economic and societal conditions retirement is being discouraged (Ford &Orel, 2005). These individuals will continue to work for their employer and to be viable they may be willing to take on job-related training. An important factor that can influence an individual to accept training is motivation. One aspect of motivation is the Socio-emotional Selectivity Theory framework that Carstensen, Isaacowitz, and Charles (1999) proposed. It sees...
Show moreWorkers are increasingly becoming older and due to economic and societal conditions retirement is being discouraged (Ford &Orel, 2005). These individuals will continue to work for their employer and to be viable they may be willing to take on job-related training. An important factor that can influence an individual to accept training is motivation. One aspect of motivation is the Socio-emotional Selectivity Theory framework that Carstensen, Isaacowitz, and Charles (1999) proposed. It sees time as fundamental to motivation, suggesting that people with shorter time frames will seek emotional gratifications and those with longer frames will prefer information seeking gratification to further their careers. I tested predictions from this framework. Individuals with shorter time frames until retirement should be less willing to participate in job-related training than those with longer time frames. After running regressions using data from Workforce Ageing in the New Economy (WANE) data set and taking into account additional factors such as the correlation of age with time until retirement and excluding those with extreme amounts of training, there was little support for this assumption. However, there is a trend in the right direction. Further studies need to be done to investigate types of training given, reasons for retirement at chosen time, personality, within different industries and firm sizes.
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Date Issued
2009
Identifier
FSU_migr_uhm-0111
Format
Thesis
Wisdom : a novella
Title
Wisdom : a novella.
Creator
Perry, Barbara L.
Date Issued
1997
Identifier
157175, FSDT157175, fsu:17298
Format
Document (PDF)
Within the checkpoints: Palestinian voices on the other side of peace and pain
Title
Within the checkpoints: Palestinian voices on the other side of peace and pain.
Creator
Glauch, Natasha Marie
Date Issued
1996
Identifier
158507, FSDT158507, fsu:17979
Format
Document (PDF)
Witness of her time: a comparative analysis of Zora Neale Hurston and Marjory Stoneman Douglas.
Title
Witness of her time: a comparative analysis of Zora Neale Hurston and Marjory Stoneman Douglas.
Creator
Browning, Tonya J.
Date Issued
1991
Identifier
157583, FSDT157583, fsu:17492
Format
Document (PDF)
Wolf Jones
Title
Wolf Jones.
Creator
Pelles, Malcolm
Date Issued
2000
Identifier
159675, FSDT159675, fsu:18545
Format
Document (PDF)
Woman, the state, and war: an evaluation of Western feminist international relations theory
Title
Woman, the state, and war: an evaluation of Western feminist international relations theory.
Creator
Salib, Mona Lisa
Date Issued
2004
Identifier
160216, FSDT160216, fsu:18808
Format
Document (PDF)
Women airforce service pilots: A study of national crises and gender ideology
Title
Women airforce service pilots: A study of national crises and gender ideology.
Creator
Moon, Melissa
Date Issued
1999
Identifier
159447, FSDT159447, fsu:18433
Format
Document (PDF)
Women and the East St. Louis Race Riot of 1917
Title
Women and the East St. Louis Race Riot of 1917.
Creator
Robinson, Kathryn Elaine
Date Issued
2016-04-27
Identifier
FSU_libsubv1_scholarship_submission_1461799049
Format
Thesis
Women and transformational leadership.
Title
Women and transformational leadership.
Creator
Vanderwerf, Alena C.
Date Issued
2007-07-13
Identifier
160743, FSDT160743, fsu:19054
Format
Document (PDF)
Women in the Age of the Hundred Years War
Title
Women in the Age of the Hundred Years War.
Creator
Cannon, Jonathan William
Abstract/Description
This paper is an analysis on the autonomy and depiction of women in the Later Middle Ages. It will cover a period of over a hundred years with specific attention paid to the literature in this time period, which will be further supported by secondary sources to resolve gaps of knowledge. This was also the period in which the Hundred Years War (1337-1453) was waged and from where the English and French case studies of this paper originate. This century is important for context in the Later...
Show moreThis paper is an analysis on the autonomy and depiction of women in the Later Middle Ages. It will cover a period of over a hundred years with specific attention paid to the literature in this time period, which will be further supported by secondary sources to resolve gaps of knowledge. This was also the period in which the Hundred Years War (1337-1453) was waged and from where the English and French case studies of this paper originate. This century is important for context in the Later Middle Ages as this was a point in history that had a number of key events such as the Black Death as well as being one of the best preserved in terms of sources available.What this paper uncovered was that while in the Later Middle Ages women from both upper and lower classes were able to a certain extent act as independent agents; this was not reflected in the contemporary literature until towards the end of this period. By the end of this period however there was an increasing number of women that were detailed and credited for their actions without being compared to their male relatives, as being described as virtuous (as opposed to evil) because of their feminine traits, and that more classes of women were being represented within the literature.
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Date Issued
2019-05-03
Identifier
FSU_libsubv1_scholarship_submission_1557433266_a2827df1
Format
Thesis
Women Warriors
Title
Women Warriors: Defending Aizu During the Boshin War (1868-1869).
Creator
Trumble, Erin
Abstract/Description
The role of 19th century Japanese women is often misinterpreted by the West. While the late Tokugawa period was certainly a patriarchy, women of the samurai class were commonly taught how to wield weapons and defend their homes. This is particularly evident in the Battle of Aizu Wakamatsu during the Boshin War where women were very active in the fighting. This study hopes to understand the culture around these women at the time of the battle, and also look at their place in contemporary...
Show moreThe role of 19th century Japanese women is often misinterpreted by the West. While the late Tokugawa period was certainly a patriarchy, women of the samurai class were commonly taught how to wield weapons and defend their homes. This is particularly evident in the Battle of Aizu Wakamatsu during the Boshin War where women were very active in the fighting. This study hopes to understand the culture around these women at the time of the battle, and also look at their place in contemporary popular culture. To investigate this, I have gathered and read secondary sources regarding women in Japan and their role among warriors. In addition, I traveled to Japan to find primary sources and to visit sites pertinent to my research, such as the Tsurugajo Castle in Aizu Wakamatsu. I have also begun reading the translation of the memoirs of one of the women who fought at Aizu, Yamamoto Yaeko. To learn of their portrayal in popular culture, I have read a manga and watched a Taiga Drama, both of which focus on telling the story of Yamamoto Yaeko. Thus far, my research demonstrates that it was fairly common for women of the samurai class to learn martial arts. However, it was less common that they would participate in actual battles and the women of Aizu and others like them appear to be the exception to the rule.
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Date Issued
2017-04-27
Identifier
FSU_libsubv1_scholarship_submission_1493409157
Format
Thesis
WOMEN’S HIGHER EDUCATION IN THE 1920s: A COMPARATIVE STUDY OF THE FLORIDA STATE COLLEGE FOR WOMEN AND RADCLIFFE COLLEGE
Title
WOMEN’S HIGHER EDUCATION IN THE 1920s: A COMPARATIVE STUDY OF THE FLORIDA STATE COLLEGE FOR WOMEN AND RADCLIFFE COLLEGE.
Creator
Sebold, Keara Lorraine
Date Issued
11/08/19
Identifier
FSU_libsubv1_scholarship_submission_1574369654_aa87c3c4
Format
Thesis
Women’s STEM Success in Biomedical Science Graduate Programs
Title
Women’s STEM Success in Biomedical Science Graduate Programs: An Exploratory Study.
Creator
Short, Jessica
Date Issued
2020-11-25
Identifier
FSU_libsubv1_scholarship_submission_1606324852_d7fa3ea8
Format
Thesis
Women, poetry, and their place in nineteenth century Germany
Title
Women, poetry, and their place in nineteenth century Germany.
Creator
Ramos, Ulrike C.
Date Issued
2003
Identifier
160118, FSDT160118, fsu:18760
Format
Document (PDF)
Word retrieval and cognitive variability in aphasia
Title
Word retrieval and cognitive variability in aphasia.
Creator
White, Sarah E.
Date Issued
2003
Identifier
160008, FSDT160008, fsu:18707
Format
Document (PDF)
Wordsworth's resurrection of the pastoral tradition
Title
Wordsworth's resurrection of the pastoral tradition.
Creator
Mullin, Janet K.
Date Issued
1977
Identifier
159307, FSDT159307, fsu:18369
Format
Document (PDF)
Working memory effects on non-native speech learning by older adults
Title
Working memory effects on non-native speech learning by older adults.
Creator
Weiner, Jessica
Date Issued
2017-04-28
Identifier
FSU_libsubv1_scholarship_submission_1493395097
Format
Thesis
Writing in the Discipline for the Studio Art Undergraduate
Title
Writing in the Discipline for the Studio Art Undergraduate.
Creator
Miller, Laura
Abstract/Description
This thesis analyzes applications of Writing Across the Curriculum (WAC) and Writing in the Discipline (WID) initiatives in undergraduate Studio Art curriculum as a heuristic tool to improve student’s visual art practice and prepare them for graduate-level writing. Scholars involved in Studio Art MFA programs have noted graduate students’ difficulty at adopting writing as a part of their creative practice, but they focus on addressing the issue at the graduate level rather than scaffolding...
Show moreThis thesis analyzes applications of Writing Across the Curriculum (WAC) and Writing in the Discipline (WID) initiatives in undergraduate Studio Art curriculum as a heuristic tool to improve student’s visual art practice and prepare them for graduate-level writing. Scholars involved in Studio Art MFA programs have noted graduate students’ difficulty at adopting writing as a part of their creative practice, but they focus on addressing the issue at the graduate level rather than scaffolding undergraduate curriculum to support students’ transition to upper division writing. This thesis argues that writing instruction should be incorporated into Studio Art undergraduate study to prepare students for careers and further study in the arts while improving their art practice through introspective journaling, research, and revision. This research features assignments and exercises from WAC/WID scholarship that meet the needs of visual art students based on various rhetorical situations, genres, and discourse communities. I included a public writing assignment, reflection exercises, and exphrastic writing as appropriate writing assignments for studio art undergraduates because they allow students to explore their own art within the broader cultural landscape as well as develop their own critical voice as participants in their discourse community.
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Date Issued
2018-04-25
Identifier
FSU_libsubv1_scholarship_submission_1524684997_12483b7d
Format
Thesis
Wulfstan's Sermo Lupi ad Anglos : an electronic hypertext edition
Title
Wulfstan's Sermo Lupi ad Anglos : an electronic hypertext edition.
Creator
Bernstein, Melissa Joy
Date Issued
1996
Identifier
157781, FSDT157781, fsu:17588
Format
Document (PDF)
X-ray diffraction analysis of gel/micellar systems
Title
An X-ray diffraction analysis of gel/micellar systems.
Creator
Wood, Wendy
Date Issued
1998
Identifier
157975, FSDT157975, fsu:17700
Format
Document (PDF)
X-ray Structure Determination of Complexes of Alzheimer's Amyloid-Beta Peptide with Oligomerization Inhibitors
Title
X-ray Structure Determination of Complexes of Alzheimer's Amyloid-Beta Peptide with Oligomerization Inhibitors.
Creator
Cotter, Robert
Abstract/Description
Alzheimer’s Disease affects millions of patients throughout the world and has widespread, debilitating impacts on patients and their loved ones.1 Current efforts to study the accumulation of the peptide amyloid-beta in interneural spaces and possible mechanisms of amyloid clearance appear promising for the development of future therapies.2 Several small biomolecules with anti-inflammatory and anti-oxidative properties have been shown to impact the aggregation of amyloid-beta and are thus...
Show moreAlzheimer’s Disease affects millions of patients throughout the world and has widespread, debilitating impacts on patients and their loved ones.1 Current efforts to study the accumulation of the peptide amyloid-beta in interneural spaces and possible mechanisms of amyloid clearance appear promising for the development of future therapies.2 Several small biomolecules with anti-inflammatory and anti-oxidative properties have been shown to impact the aggregation of amyloid-beta and are thus candidates for future drug development, targeting the amyloidogenic, inflammatory, and oxidative stress components of Alzheimer’s pathology.3-6 This study aims to determine the regions on amyloid-beta to which Vitamin B12 binds using X-ray crystallography and diffraction analysis. Literature reviews were conducted to find optimal solution conditions to solubilize amyloid-beta and previously documented interactions between the two molecules. Buffer screens were then carried out and a buffer was selected for subsequent crystallization trials. Crystals of Vitamin B12 and Vitamin B12 with amyloid-beta were generated via hanging drop vapor-diffusion crystallization. Crystals were diffracted using the AMX-17ID-1 beamline of the National Synchrotron Light Source II at Brookhaven National Laboratory, and a structure was determined from one of our crystals of Vitamin B12 and amyloid-beta. Though no amyloid-beta was observed in the unit cell of Vitamin B12 determined from the sample, significant observed heterogeneity in the unit cell warrants further study of these potential complexes. We are currently pursuing the determination of structures from our remaining crystals and the generation of new samples of amyloid-beta and various other small biomolecules demonstrated to impact amyloid-beta’s aggregation.
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Date Issued
2019-04-05
Identifier
FSU_libsubv1_scholarship_submission_1555018134_e5304f68
Format
Thesis
Year With Less Taxes
Title
A Year With Less Taxes: The Impact of the 2019 Excise Tax Reduction on the Coal Industry.
Creator
Shost, Garrett
Date Issued
2020-04-23
Identifier
FSU_libsubv1_scholarship_submission_1587667612_4233b507
Format
Thesis
Yeast two-hybrid investigation of NBD1 and NBD2
Title
Yeast two-hybrid investigation of NBD1 and NBD2.
Creator
Flynn, Andrea N.
Date Issued
2002
Identifier
159874, FSDT159874, fsu:18640
Format
Document (PDF)
Yiddishekite Concerto (for violin and chamber/reduced orchestra)
Title
The Yiddishekite Concerto (for violin and chamber/reduced orchestra).
Creator
Pittard, Mai Li
Date Issued
2005-08-03
Identifier
FSDT160357_parent
Format
Set of related objects
You've Earned It! Searching for a Defensible Basis for Desert in Wages
Title
You've Earned It! Searching for a Defensible Basis for Desert in Wages.
Creator
Jenkins, Ryan
Abstract/Description
In my thesis, I propose a new theory of wages as deserved income. I take a look at two prominent philosophers’ discussions on the subject, and find they are both lacking. George Sher believes that desert in wages can best be explained by appealing to the violation of moral standards that dictate how we believe the world should be. He says that, because subordinating our labor to another’s ends (i.e. ‘working’) violates some “independent standard,” wages are deserved to offset this loss of...
Show moreIn my thesis, I propose a new theory of wages as deserved income. I take a look at two prominent philosophers’ discussions on the subject, and find they are both lacking. George Sher believes that desert in wages can best be explained by appealing to the violation of moral standards that dictate how we believe the world should be. He says that, because subordinating our labor to another’s ends (i.e. ‘working’) violates some “independent standard,” wages are deserved to offset this loss of autonomy. A wage is “uniquely suited” to allow a worker to pursue his own goals in turn, says Sher. Joel Feinberg argues that, as far as wages are deserved at all, they are deserved only as compensation for especially difficult, dangerous or unpleasant work, and that they can only explain deserved differentials in pay. He rejects the idea that deserved wages can be explained as a reward. My own theory, briefly, is this: wages are deserved as a reward after a worker has (1) put forth an effort that (2) has been directed toward the end of another and (3) is socially valuable. Finally, I survey the literature in the living wage movement. Finding it lacking in the language of desert, I propose that the proponents of a living wage adopt an argument like mine. That is, I suggest they give to desert a more central role in their discussions about why workers should receive a living wage.
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Date Issued
2008-11-12
Identifier
210372, FSDT210372, fsu:19178
Format
Document (PDF)
Your Diligent Looking Discover the Lacking
Title
Your Diligent Looking Discover the Lacking: Individual and Societal Reconciliation in Isherwood and Auden's 1930S Literature.
Creator
Lonsberry, Samuel, Department of English
Abstract/Description
The work aims to explore the similarities and differences between Christopher Isherwood and W.H. Auden's 1930s literature. As unique authors within the decade, emphasizing artifice and aesthetics in relation to socially-conscious writing, both artists provide an interesting study of one sub-category of 1930s literature. Defining themselves against the likes of George Orwell and Aldous Huxley, Auden and Isherwood attempt to retain the aesthetic-driven forms of 1920s Modernism while further...
Show moreThe work aims to explore the similarities and differences between Christopher Isherwood and W.H. Auden's 1930s literature. As unique authors within the decade, emphasizing artifice and aesthetics in relation to socially-conscious writing, both artists provide an interesting study of one sub-category of 1930s literature. Defining themselves against the likes of George Orwell and Aldous Huxley, Auden and Isherwood attempt to retain the aesthetic-driven forms of 1920s Modernism while further melding them with more politically focused cultural trends.
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Date Issued
2015
Identifier
FSU_migr_uhm-0506
Format
Thesis
Youth in our time: a study of juvenile deliquency trends in the United States and in Gainesville and Alachua county, Florida, 1939-1945
Title
Youth in our time: a study of juvenile deliquency trends in the United States and in Gainesville and Alachua county, Florida, 1939-1945.
Creator
Bell, Betty
Date Issued
1946
Identifier
159052, FSDT159052, fsu:18245
Format
Document (PDF)
ZIKV AND DENV DIFFERENTIALLY PERTURB ISG15 DESPITE SIMILAR RESTRICTION BY INTERFERON
Title
ZIKV AND DENV DIFFERENTIALLY PERTURB ISG15 DESPITE SIMILAR RESTRICTION BY INTERFERON.
Creator
Sherman, Allaura
Date Issued
2016-04-15
Identifier
FSU_libsubv1_scholarship_submission_1461944782
Format
Thesis
Zinc Regulation of Bone Marrow-Derived Mesenchymal Stem Cell Neuronal Differentiation
Title
Zinc Regulation of Bone Marrow-Derived Mesenchymal Stem Cell Neuronal Differentiation.
Creator
Faye, Sari, Department of Chemistry and Biochemistry
Abstract/Description
The multipotent ability of mesenchymal stem cells (MSC) to differentiate into a large variety of mature cell types gives them a high potential for use in a variety of therapeutic purposes. Recently, it was discovered that bone marrow derived MSC could be induced to take on a neuronal phenotype through the addition of cobalt chloride (CoCl2) to the growth media. It is also well known that the trace element zinc is vital for both neuronal proliferation and differentiation from neuronal...
Show moreThe multipotent ability of mesenchymal stem cells (MSC) to differentiate into a large variety of mature cell types gives them a high potential for use in a variety of therapeutic purposes. Recently, it was discovered that bone marrow derived MSC could be induced to take on a neuronal phenotype through the addition of cobalt chloride (CoCl2) to the growth media. It is also well known that the trace element zinc is vital for both neuronal proliferation and differentiation from neuronal precursor cells. Thus, this work tested the hypothesis that zinc plays a role in the differentiation of MSC into neurons. Secondly, because zinc is unable to enter or exit cells without the assistance of zinc transport proteins (ZnT), this work tested the hypothesis that two transport proteins, ZnT-1 and ZnT-4, would be regulated both by zinc and by treatment with cobalt. This work used both cell morphology and markers of neuronal differentiation (TuJ1 and neuronal specific enolase) to show that zinc deficiency (ZD) combined with CoCl2 treatment appeared to induce differentiation of rat MSC. Furthermore, the zinc transporters were differentially regulated such that ZnT-4 was increased on the cell membrane by zinc deficiency, while ZnT-1 levels at the membrane were highest in the combined zinc deficiency-cobalt treatment group. These data implicate zinc in the mechanisms associated with MSC function.
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Date Issued
2013
Identifier
FSU_migr_uhm-0235
Format
Thesis
Zinc Regulation of Mesenchymal Stem Cell Proliferation and Survival
Title
Zinc Regulation of Mesenchymal Stem Cell Proliferation and Survival.
Creator
Hagler, Shaye, Department of Chemistry and Biochemistry
Abstract/Description
Mesenchymal stem cells (MSC) have a wide variety of promising clinical applications including the treatment of brain disorders and injury, cardiovascular disease, and cancer. To fully exploit their potential, we need a better understanding of the cellular and molecular mechanisms that govern stem cell division and survival. We have hypothesized that the essential trace element zinc regulates the proliferation and survival of rat and human bone marrow-derived MSC. Proliferation of MSC is...
Show moreMesenchymal stem cells (MSC) have a wide variety of promising clinical applications including the treatment of brain disorders and injury, cardiovascular disease, and cancer. To fully exploit their potential, we need a better understanding of the cellular and molecular mechanisms that govern stem cell division and survival. We have hypothesized that the essential trace element zinc regulates the proliferation and survival of rat and human bone marrow-derived MSC. Proliferation of MSC is impaired by zinc deficiency. For example, after 48h of zinc deficiency, proliferation was reduced by 50% (p
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Date Issued
2013
Identifier
FSU_migr_uhm-0181
Format
Thesis
Zymosan Fungal Infection Induces Nucleosome Redistributions During the Innate Immune Response
Title
Zymosan Fungal Infection Induces Nucleosome Redistributions During the Innate Immune Response.
Creator
Gruder, Olivia, Dennis, Jonathan, Department of Biological Science
Abstract/Description
Chromatin structure plays a critical role in the regulation of the human genome. An understanding of the role of chromatin structure and its relationship to gene regulation is critical to developing new strategies to prevent and treat diseases. We chose to investigate the anti-inflammatory response of human macrophage like cell line (THP1) to Zymosan, in order to elucidate the regulation of chromatin. Zymosan is a component the fungal cell wall that induces an innate immune response. After...
Show moreChromatin structure plays a critical role in the regulation of the human genome. An understanding of the role of chromatin structure and its relationship to gene regulation is critical to developing new strategies to prevent and treat diseases. We chose to investigate the anti-inflammatory response of human macrophage like cell line (THP1) to Zymosan, in order to elucidate the regulation of chromatin. Zymosan is a component the fungal cell wall that induces an innate immune response. After THP1 were treated with zymosan, we hypothesized that the fungal infection would initiate an inflammatory response by altering nucleosome redistribution and/or altering chromatin structure in a time dependent manner. Based on previous results that showed rapid, widespread, transient changes in nucleosome distribution in the innate immune response, we chose to look at multiple time points at high temporal resolution: 0 (control), 20', 40', 60', 80', 100', 2h, 3h, 4h and 12h. We measured nucleosome distribution at each of these time points at hundreds of genes transcription start sites involved in the immune response. nucleosome distribution changes in the innate immune response to fungal infection.
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Date Issued
2014
Identifier
FSU_migr_uhm-0312
Format
Thesis
βTRCP
Title
βTRCP: Linking Circadian Rhythms and Metabolism.
Creator
Sweeney, Megan C., Department of Biomedical Sciences
Abstract/Description
Shifts in circadian rhythms, like in shift work or jet lag, have been shown to increase the risk of many metabolic disorders. Therefore, it is not surprising that many genes involved in the circadian clock mechanism have demonstrated a regulatory role in metabolism. It has been shown that E3 ubiquitin ligases can influence metabolism as well. In initial studies, my lab created a knockout of two E3 ubiquitin ligases thought to be essential to the clock, βTRCP1/2, in a mouse model in order to...
Show moreShifts in circadian rhythms, like in shift work or jet lag, have been shown to increase the risk of many metabolic disorders. Therefore, it is not surprising that many genes involved in the circadian clock mechanism have demonstrated a regulatory role in metabolism. It has been shown that E3 ubiquitin ligases can influence metabolism as well. In initial studies, my lab created a knockout of two E3 ubiquitin ligases thought to be essential to the clock, βTRCP1/2, in a mouse model in order to study the proteasomal degradation machinery in mammals. Upon characterizing the circadian phenotype of this mouse, we noticed an unprecedented, metabolic phenotype after deletion of these vital ligases. These novel mutant mice lose over 30% of their body weight within 5 days while still maintaining an eating and drinking regime similar to wild-type mice. In this project, in vivo and sequence analysis studies aimed to look further into the causes of this phenomenon and the molecular mechanisms underlying them.
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Date Issued
2015
Identifier
FSU_migr_uhm-0455
Format
Thesis
Φ-Value Analysis of Symfoil-4T
Title
Φ-Value Analysis of Symfoil-4T.
Creator
Sutherland, Mason A., Department of Biological Science
Abstract/Description
A critical consideration in the process of de novo protein architecture design and protein evolution is the folding pathway and behavior a protein undertakes in transitioning to its functional tertiary structure. Of particular interest is a cryptic element within protein primary structure that enables an efficient folding pathway, and is postulated to be a heritable element in the evolution of protein architecture, the "folding nucleus" (FN). However, almost nothing is known regarding how the...
Show moreA critical consideration in the process of de novo protein architecture design and protein evolution is the folding pathway and behavior a protein undertakes in transitioning to its functional tertiary structure. Of particular interest is a cryptic element within protein primary structure that enables an efficient folding pathway, and is postulated to be a heritable element in the evolution of protein architecture, the "folding nucleus" (FN). However, almost nothing is known regarding how the FN changes as simpler peptide motifs join to form more complex polypeptides. To this effect, the structure and folding properties of foldable intermediates along the evolutionary trajectory of the β-trefoil protein type were tested. This study specifically used and compared data from Symfoil-4T (an engineered β-trefoil protein) to several mutants to show that the FN is acquired during gene fusion events, incorporating novel turn structure generated by gene fusion. Furthermore, the FN of β-trefoils are adjusted by circular permutation in response to destabilizing functional mutations to allow the survival of FN (which is made possible by the intrinsic C3 cyclic symmetry of β-trefoil architecture) identifying a selective advantage that helps explain extant cyclic structural symmetry in the proteome.
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Date Issued
2015
Identifier
FSU_migr_uhm-0453
Format
Thesis
Picture Superiority Effect on Encoding and Reminding
Title
Picture Superiority Effect on Encoding and Reminding
Abstract/Description
Recent literature has demonstrated that if someone studies one list of word pairs followed by another list of word pairs in which the second half of some of the pairs have changed (e.g., they saw “knee-bone” on the first list and “knee-bend” on the second list), this change can remind them of the pair’s presence on the original list and improve memory performance for both of the pairs. Previously, this kind of design would lead researchers to observe interference, which would cause memory...
Show moreRecent literature has demonstrated that if someone studies one list of word pairs followed by another list of word pairs in which the second half of some of the pairs have changed (e.g., they saw “knee-bone” on the first list and “knee-bend” on the second list), this change can remind them of the pair’s presence on the original list and improve memory performance for both of the pairs. Previously, this kind of design would lead researchers to observe interference, which would cause memory performance to suffer; the discovery of the memory enhancing effects of reminders inspired further research to understand how their underlying mechanisms and what makes them more likely to occur. The presented research examines whether picture-word pairs will trigger more remindings than word-word pairs on the presumption that the picture superiority effect will play an important role. The results indicate that participants did experience more remindings for the picture-word pairs than for the word-word pairs and that better memory performance for picture-word pairs is due to a combination of this effect and an encoding effect.
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Identifier
FSU_libsubv1_scholarship_submission_1524707531_55417f4e
Format
Thesis

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